Skip to main content


Page 61 of 67

  1. The thermotolerant methylotrophic yeast Hansenula polymorpha is capable of alcoholic fermentation of xylose at elevated temperatures (45 – 48°C). Such property of this yeast defines it as a good candidate for the...

    Authors: Olena V Dmytruk, Kostyantyn V Dmytruk, Charles A Abbas, Andriy Y Voronovsky and Andriy A Sibirny
    Citation: Microbial Cell Factories 2008 7:21
  2. Selection of an appropriate host organism is crucial for the economic success of biotechnological processes. A generally important selection criterion is a low maintenance energy metabolism to reduce non-produ...

    Authors: Simon Tännler, Seraina Decasper and Uwe Sauer
    Citation: Microbial Cell Factories 2008 7:19
  3. Considerable interest in the bioconversion of lignocellulosic biomass into ethanol has led to metabolic engineering of Saccharomyces cerevisiae for fermentation of xylose. In the present study, the transcriptome ...

    Authors: Laura Salusjärvi, Matti Kankainen, Rabah Soliymani, Juha-Pekka Pitkänen, Merja Penttilä and Laura Ruohonen
    Citation: Microbial Cell Factories 2008 7:18
  4. Tropane alkaloids, mainly hyoscyamine and scopolamine, are widely used in medicine due to their anticholinergic activity. Scopolamine has a higher demand being the more valuable alkaloid due to its fewer side ...

    Authors: Alejandra B Cardillo, Julián Rodríguez Talou and Ana M Giulietti
    Citation: Microbial Cell Factories 2008 7:17
  5. Lipolysis is an important process of cheese ripening that contributes to the formation of flavour. Propionibacterium freudenreichii is the main agent of lipolysis in Emmental cheese; however, the enzymes involved...

    Authors: Julien Dherbécourt, Hélène Falentin, Stéphane Canaan and Anne Thierry
    Citation: Microbial Cell Factories 2008 7:16
  6. High salinity (1–10% w/v) of tannery wastewater makes it difficult to be treated by conventional biological treatment. Salt tolerant microbes can adapt to these saline conditions and degrade the organics in sa...

    Authors: Senthilkumar Sivaprakasam, Surianarayanan Mahadevan, Sudharshan Sekar and Susheela Rajakumar
    Citation: Microbial Cell Factories 2008 7:15
  7. Introducing point mutations into bacterial chromosomes is important for further progress in studies relying on functional genomics, systems- and synthetic biology, and for metabolic engineering. For many inves...

    Authors: Ralf Heermann, Tim Zeppenfeld and Kirsten Jung
    Citation: Microbial Cell Factories 2008 7:14
  8. Biopharmaceutical drugs are mainly recombinant proteins produced by biotechnological tools. The patents of many biopharmaceuticals have expired, and biosimilars are thus currently being developed. Human granul...

    Authors: Ana LS Vanz, Gaby Renard, Mario S Palma, Jocelei M Chies, Sérgio L Dalmora, Luiz A Basso and Diógenes S Santos
    Citation: Microbial Cell Factories 2008 7:13
  9. Different species of microorganisms including yeasts, filamentous fungi and bacteria have been used in the past 25 years for the controlled production of foreign proteins of scientific, pharmacological or indu...

    Authors: Brigitte Gasser, Markku Saloheimo, Ursula Rinas, Martin Dragosits, Escarlata Rodríguez-Carmona, Kristin Baumann, Maria Giuliani, Ermenegilda Parrilli, Paola Branduardi, Christine Lang, Danilo Porro, Pau Ferrer, Maria Luisa Tutino, Diethard Mattanovich and Antonio Villaverde
    Citation: Microbial Cell Factories 2008 7:11
  10. The Gram-positive bacterium Bacillus subtilis is an important producer of high quality industrial enzymes and a few eukaryotic proteins. Most of these proteins are secreted into the growth medium, but successful ...

    Authors: Jessica C Zweers, Imrich Barák, Dörte Becher, Arnold JM Driessen, Michael Hecker, Vesa P Kontinen, Manfred J Saller, L'udmila Vavrová and Jan Maarten van Dijl
    Citation: Microbial Cell Factories 2008 7:10
  11. Metabolic engineering of Saccharomyces cerevisiae for xylose fermentation into fuel ethanol has oftentimes relied on insertion of a heterologous pathway that consists of xylose reductase (XR) and xylitol dehydrog...

    Authors: Barbara Petschacher and Bernd Nidetzky
    Citation: Microbial Cell Factories 2008 7:9
  12. Heterologous protein expression in microorganisms may contribute to identify and demonstrate antifungal activity of novel proteins. The Solanum nigrum osmotin-like protein (SnOLP) gene encodes a member of pathoge...

    Authors: Magnóliade A Campos, Marilia S Silva, Cláudio P Magalhães, Simone G Ribeiro, Rafael PD Sarto, Eduardo A Vieira and Maria F Grossi de Sá
    Citation: Microbial Cell Factories 2008 7:7
  13. Recombinant protein production in Escherichia coli cells is a complex process, where among other parameters, plasmid copy number, structural and segregational stability of plasmid have an important impact on the ...

    Authors: Mihaela Škulj, Veronika Okršlar, Špela Jalen, Simona Jevševar, Petra Slanc, Borut Štrukelj and Viktor Menart
    Citation: Microbial Cell Factories 2008 7:6
  14. Overflow metabolism is an undesirable characteristic of aerobic cultures of Saccharomyces cerevisiae during biomass-directed processes. It results from elevated sugar consumption rates that cause a high substrate...

    Authors: Fernanda Badotti, Marcelo G Dário, Sergio L Alves Jr, Maria Luiza A Cordioli, Luiz C Miletti, Pedro S de Araujo and Boris U Stambuk
    Citation: Microbial Cell Factories 2008 7:4
  15. Astaxanthin is a xanthophyll of great interest in animal nutrition and human health. The market prospect in the nutraceutics industries for this health-protective molecule is very promising. Astaxanthin is syn...

    Authors: Juan F Martín, Eduardo Gudiña and José L Barredo
    Citation: Microbial Cell Factories 2008 7:3
  16. In a previous paper, we reported the accomplishment of a cold gene-expression system for the recombinant secretion of heterologous proteins in Pseudoalteromonas haloplanktis TAC125. This system makes use of the p...

    Authors: Ermenegilda Parrilli, Daniela De Vizio, Claudia Cirulli and Maria Luisa Tutino
    Citation: Microbial Cell Factories 2008 7:2
  17. Escherichia coli strains lacking the phosphoenolpyruvate: carbohydrate phosphotransferase system (PTS) are capable of coutilizing glucose and other carbon sources due to the absence of catabolite repression by gl...

    Authors: Karla Martínez, Ramón de Anda, Georgina Hernández, Adelfo Escalante, Guillermo Gosset, Octavio T Ramírez and Francisco G Bolívar
    Citation: Microbial Cell Factories 2008 7:1
  18. Leptospirosis is a serious infection disease caused by pathogenic strains of the Leptospira spirochetes, which affects not only humans but also animals. It has long been expected to find an effective vaccine to p...

    Authors: Zhijun Wang, Li Jin and Alicja Węgrzyn
    Citation: Microbial Cell Factories 2007 6:39
  19. The demand on antigen binding reagents in research, diagnostics and therapy raises questions for novel antibody formats as well as appropriate production systems. Recently, the novel single chain Fab (scFab) a...

    Authors: Eva Jordan, Laila Al-Halabi, Thomas Schirrmann, Michael Hust and Stefan Dübel
    Citation: Microbial Cell Factories 2007 6:38
  20. The Saccharopolyspora erythraea genome sequence, recently published, presents considerable divergence from those of streptomycetes in gene organization and function, confirming the remarkable potential of S. eryt...

    Authors: Clelia Peano, Silvio Bicciato, Giorgio Corti, Francesco Ferrari, Ermanno Rizzi, Raoul JP Bonnal, Roberta Bordoni, Alberto Albertini, Luigi Rossi Bernardi, Stefano Donadio and Gianluca De Bellis
    Citation: Microbial Cell Factories 2007 6:37
  21. Human α1-proteinase inhibitor (α1-PI), also known as antitrypsin, is the most abundant serine protease inhibitor (serpin) in plasma. Its deficiency is associated with development of progressive, ultimately fatal ...

    Authors: Elena Karnaukhova, Yakir Ophir, Loc Trinh, Nimish Dalal, Peter J Punt, Basil Golding and Joseph Shiloach
    Citation: Microbial Cell Factories 2007 6:34
  22. The yeast Saccharomyces cerevisiae is a well-established model system for understanding fundamental cellular processes relevant to higher eukaryotic organisms. Less known is its value for virus research, an area ...

    Authors: Rui P Galao, Nicoletta Scheller, Isabel Alves-Rodrigues, Tanja Breinig, Andreas Meyerhans and Juana Díez
    Citation: Microbial Cell Factories 2007 6:32
  23. The increasing commercial demand for L-carnitine has led to a multiplication of efforts to improve its production with bacteria. The use of different cell environments, such as growing, resting, permeabilized,...

    Authors: Vicente Bernal, Ángel Sevilla, Manuel Cánovas and José L Iborra
    Citation: Microbial Cell Factories 2007 6:31
  24. The rational design of L-phenylalanine (L-Phe) overproducing microorganisms has been successfully achieved by combining different genetic strategies such as inactivation of the phosphoenolpyruvate: phosphotran...

    Authors: José Luis Báez-Viveros, Noemí Flores, Katy Juárez, Patricia Castillo-España, Francisco Bolivar and Guillermo Gosset
    Citation: Microbial Cell Factories 2007 6:30
  25. Thioredoxin (TRX) is a powerful disulfide oxido-reductase that catalyzes a wide spectrum of redox reactions in the cell. The aim of this study is to elucidate the role of the TRX system in the oxidative stress...

    Authors: L Mariela Serrano, Douwe Molenaar, Michiel Wels, Bas Teusink, Peter A Bron, Willem M de Vos and Eddy J Smid
    Citation: Microbial Cell Factories 2007 6:29
  26. Natural allergen sources can supply large quantities of authentic allergen mixtures for use as immunotherapeutics. However, such extracts are complex, difficult to define, vary from batch to batch, which may l...

    Authors: Jacob Glenting, Lars K Poulsen, Kentaro Kato, Søren M Madsen, Hanne Frøkiær, Camilla Wendt and Helle W Sørensen
    Citation: Microbial Cell Factories 2007 6:28
  27. It is now more than 10 years since the publication of the first microbial genome sequence and science is now moving towards a post genomic era with transcriptomics and proteomics offering insights into cellula...

    Authors: Robert LJ Graham, Ciaren Graham and Geoff McMullan
    Citation: Microbial Cell Factories 2007 6:26
  28. Exposure to nickel (Ni) and its chemical derivatives has been associated with severe health effects in human. On the contrary, poor knowledge has been acquired on target physiological processes or molecular me...

    Authors: Anna M Salzano, Ferdinando Febbraio, Tiziana Farias, Giovanni P Cetrangolo, Roberto Nucci, Andrea Scaloni and Giuseppe Manco
    Citation: Microbial Cell Factories 2007 6:25
  29. An important objective in developing new drugs is the achievement of high specificity to maximize curing effect and minimize side-effects, and high specificity is an integral part of the antisense approach. Th...

    Authors: Louise Carøe Vohlander Rasmussen, Hans Uffe Sperling-Petersen and Kim Kusk Mortensen
    Citation: Microbial Cell Factories 2007 6:24
  30. For many microbial processes, the complexity of the metabolisms and the responses to transient and realistic conditions are difficult to capture in mechanistic models. The cells seem to have an innate intellig...

    Authors: Pratap R Patnaik
    Citation: Microbial Cell Factories 2007 6:23
  31. Human immune cells generate large amounts of reactive oxygen species (ROS) throughout the respiratory burst that occurs during inflammation. In inflammatory bowel diseases, a sustained and abnormal activation ...

    Authors: Tatiana Rochat, Luis Bermúdez-Humarán, Jean-Jacques Gratadoux, Christel Fourage, Christine Hoebler, Gérard Corthier and Philippe Langella
    Citation: Microbial Cell Factories 2007 6:22
  32. The analysis of transcriptional levels of the genes involved in protein synthesis and secretion is a key factor to understand the host organism's responses to recombinant protein production, as well as their i...

    Authors: David Resina, Mónika Bollók, Narendar K Khatri, Francisco Valero, Peter Neubauer and Pau Ferrer
    Citation: Microbial Cell Factories 2007 6:21
  33. Streptokinase (SK) is a potent plasminogen activator with widespread clinical use as a thrombolytic agent. It is naturally secreted by several strains of beta-haemolytic streptococci. The low yields obtained i...

    Authors: Elsa Pimienta, Julio C Ayala, Caridad Rodríguez, Astrid Ramos, Lieve Van Mellaert, Carlos Vallín and Jozef Anné
    Citation: Microbial Cell Factories 2007 6:20
  34. Corynebacterium glutamicum has several anaplerotic pathways (anaplerosis), which are essential for the productions of amino acids, such as lysine and glutamate. It is still not clear how flux changes in anaplerot...

    Authors: Tomokazu Shirai, Koki Fujimura, Chikara Furusawa, Keisuke Nagahisa, Suteaki Shioya and Hiroshi Shimizu
    Citation: Microbial Cell Factories 2007 6:19
  35. Genetic factors and a dysregulated immune response towards commensal bacteria contribute to the pathogenesis of Inflammatory Bowel Disease (IBD). Animal models demonstrated that the normal intestinal flora is ...

    Authors: Asgar Ergin, Konrad Büssow, Joachim Sieper, Andreas Thiel, Rainer Duchmann and Thomas Adam
    Citation: Microbial Cell Factories 2007 6:18
  36. Commercial medium (Pharmamedia) was investigated for the production of surfactin by Bacillus subtilis MZ-7. Different media (defined, semi-defined, and complex media) were compared for the production of surfactin...

    Authors: Muaaz Mutaz Al-Ajlani, Muhammad Abid Sheikh, Zeeshan Ahmad and Shahida Hasnain
    Citation: Microbial Cell Factories 2007 6:17
  37. Despite the fact that many reports deal with glycolysis in Lactococcus lactis, there is not much information on the regulation of uptake of glucose itself. The aim of the present work was to investigate the effec...

    Authors: Maria Papagianni, Nicholaos Avramidis and George Filiousis
    Citation: Microbial Cell Factories 2007 6:16
  38. Together with the development of optical sensors, fluorometry is becoming an increasingly attractive tool for the monitoring of cultivation processes. In this context, the green fluorescence protein (GFP) has ...

    Authors: Anna Surribas, David Resina, Pau Ferrer and Francisco Valero
    Citation: Microbial Cell Factories 2007 6:15
  39. Vanillin is one of the most important aromatic flavour compounds used in the food and cosmetic industries. Natural vanillin is extracted from vanilla beans and is relatively expensive. Moreover, the consumer d...

    Authors: Paolo Barghini, Diana Di Gioia, Fabio Fava and Maurizio Ruzzi
    Citation: Microbial Cell Factories 2007 6:13
  40. Lactic acid bacteria (LAB) are attractive tools to deliver therapeutic molecules at the mucosal level. The model LAB Lactococcus lactis has been intensively used to produce and deliver such heterologous proteins....

    Authors: Stéphane Hazebrouck, Laetitia Pothelune, Vasco Azevedo, Gérard Corthier, Jean-Michel Wal and Philippe Langella
    Citation: Microbial Cell Factories 2007 6:12
  41. All organisms living under aerobic atmosphere have powerful mechanisms that confer their macromolecules protection against oxygen reactive species. Microorganisms have developed biomolecule-protecting systems ...

    Authors: Ebert S Hanna, Maria-Cristina Roque-Barreira, Emerson S Bernardes, Ademilson Panunto-Castelo, Marcelo V Sousa, Igor C Almeida and Marcelo Brocchi
    Citation: Microbial Cell Factories 2007 6:11
  42. Saccharomyces cerevisiae is widely utilized in basic research as a model eukaryotic organism and in biotechnology as a host for heterologous protein production. Both activities demand the use of highly regulated ...

    Authors: María J Quintero, Douglas Maya, Miguel Arévalo-Rodríguez, Ángel Cebolla and Sebastián Chávez
    Citation: Microbial Cell Factories 2007 6:10

Annual Journal Metrics

  • 2022 Citation Impact
    6.4 - 2-year Impact Factor
    6.3 - 5-year Impact Factor
    1.412 - SNIP (Source Normalized Impact per Paper)
    1.091 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    75 days submission to accept (Median)

    2023 Usage 
    875 Altmetric mentions