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  1. Guanosine is a purine nucleoside that is widely used as a raw material for food additives and pharmaceutical products. Microbial fermentation is the main production method of guanosine. However, the guanosine-...

    Authors: Kun Zhang, Mengxing Qin, Yu Hou, Wenwen Zhang, Zhenyu Wang and Hailei Wang
    Citation: Microbial Cell Factories 2024 23:182
  2. Volatile compounds are key elements in the interaction and communication between organisms at both interspecific and intraspecific levels. In complex bacterial communities, the emission of these fast-acting ch...

    Authors: Lorena Cuervo, Carmen Méndez, José A. Salas, Carlos Olano and Mónica G. Malmierca
    Citation: Microbial Cell Factories 2024 23:181
  3. Nowadays, biofuels, especially bioethanol, are becoming increasingly popular as an alternative to fossil fuels. Zymomonas mobilis is a desirable species for bioethanol production due to its unique characteristics...

    Authors: Shaqayeq Asefi, Hoda Nouri, Golchehr Pourmohammadi and Hamid Moghimi
    Citation: Microbial Cell Factories 2024 23:180
  4. Human lysozyme (hLYZ) is a natural antibacterial protein with broad applications in food and pharmaceutical industries. Recombinant production of hLYZ in Komagataella phaffii (K. phaffii) has attracted considerab...

    Authors: Yong-Jun Zhong, Yang-Yang Luo, Haiyang Xia, Qing-Wei Zhao and Xu-Ming Mao
    Citation: Microbial Cell Factories 2024 23:179
  5. Computational mining of useful enzymes and biosynthesis pathways is a powerful strategy for metabolic engineering. Through systematic exploration of all conceivable combinations of enzyme reactions, including ...

    Authors: Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J. Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo and Tomohisa Hasunuma
    Citation: Microbial Cell Factories 2024 23:178
  6. Heme-incorporating peroxygenases are responsible for electron transport in a multitude of organisms. Yet their application in biocatalysis is hindered due to their challenging recombinant production. Previous ...

    Authors: Mihail Besleaga, Christian Zimmermann, Katharina Ebner, Robert L. Mach, Astrid R. Mach-Aigner, Martina Geier, Anton Glieder, Oliver Spadiut and Julian Kopp
    Citation: Microbial Cell Factories 2024 23:177
  7. Bacterial infections and the rising antimicrobial resistance pose a significant threat to public health. Pseudomonas aeruginosa produces bacteriocins like pyocins, especially S-type pyocins, which are promising f...

    Authors: Hamed Charkhian, Ehsan Soleimannezhadbari, Amin Bodaqlouei, Lida Lotfollahi, Hajie Lotfi, Nesa Yousefi, Ehsan Shojadel and Zafar Gholinejad
    Citation: Microbial Cell Factories 2024 23:175
  8. The objectives of the current study were to extract pyocyanin from Pseudomonas aeruginosa clinical isolates, characterize its chemical nature, and assess its biological activity against different bacteria and can...

    Authors: Moustafa A. Marey, Rania Abozahra, Nefertiti A. El-Nikhely, Miranda F. Kamal, Sarah M. Abdelhamid and Mohammed A. El-Kholy
    Citation: Microbial Cell Factories 2024 23:174
  9. There is increasing evidence that probiotic and commensal bacteria play a role in substrate metabolism, energy harvesting and intestinal homeostasis, and may exert immunomodulatory activities on human health. ...

    Authors: Luis G. Bermúdez-Humarán, Benoit Chassaing and Philippe Langella
    Citation: Microbial Cell Factories 2024 23:172
  10. Fibroblast growth factor 21 (FGF21) is a promising candidate for treating metabolic disorder diseases and has been used in phase II clinical trials. Currently, metabolic diseases are prevalent worldwide, under...

    Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang and Xianlong Ye
    Citation: Microbial Cell Factories 2024 23:171
  11. The gram-positive bacterium Bacillus subtilis is widely used for industrial enzyme production. Its ability to secrete a wide range of enzymes into the extracellular medium especially facilitates downstream proces...

    Authors: Jana Senger, Ines Seitl, Eva Pross and Lutz Fischer
    Citation: Microbial Cell Factories 2024 23:170
  12. In vitro expression involves the utilization of the cellular transcription and translation machinery in an acellular context to produce one or more proteins of interest and has found widespread application in ...

    Authors: Ana L. J. L. Ribeiro, Patricia Pérez-Arnaiz, Mercedes Sánchez-Costa, Lara Pérez, Marcos Almendros, Liisa van Vliet, Fabrice Gielen, Jesmine Lim, Simon Charnock, Florian Hollfelder, J. Eduardo González-Pastor, José Berenguer and Aurelio Hidalgo
    Citation: Microbial Cell Factories 2024 23:169
  13. Microbially induced calcium carbonate precipitation has been extensively researched for geoengineering applications as well as diverse uses within the built environment. Bacteria play a crucial role in produci...

    Authors: Katie A. Gilmour, Prakriti Sharma Ghimire, Jennifer Wright, Jamie Haystead, Martyn Dade-Robertson, Meng Zhang and Paul James
    Citation: Microbial Cell Factories 2024 23:168
  14. White-rot fungi are known to naturally produce high quantities of laccase, which exhibit commendable stability and catalytic efficiency. However, their laccase production does not meet the demands for industri...

    Authors: Long-Bin Zhang, Xiu-Gen Qiu, Ting-Ting Qiu, Zhou Cui, Yan Zheng and Chun Meng
    Citation: Microbial Cell Factories 2024 23:167
  15. Recombinant peptide production in Escherichia coli provides a sustainable alternative to environmentally harmful and size-limited chemical synthesis. However, in-vivo production of disulfide-bonded peptides at hi...

    Authors: Martin Gibisch, Matthias Müller, Christopher Tauer, Bernd Albrecht, Rainer Hahn, Monika Cserjan-Puschmann and Gerald Striedner
    Citation: Microbial Cell Factories 2024 23:166
  16. The increased use of biofuels in place of fossil fuels is one strategy to support the transition to net-zero carbon emissions, particularly in transport applications. However, expansion of the use of 1st gener...

    Authors: Joseph Calverley, Christopher Ibenegbu, Abdulkadir Hussein-Sheik, H. C. Hemaka Bandulasena and David J. Leak
    Citation: Microbial Cell Factories 2024 23:165
  17. Optically active D-amino acids are widely used as intermediates in the synthesis of antibiotics, insecticides, and peptide hormones. Currently, the two-enzyme cascade reaction is the most efficient way to prod...

    Authors: Fa Zhang, Muhammad Naeem, Bo Yu, Feixia Liu and Jiansong Ju
    Citation: Microbial Cell Factories 2024 23:164
  18. Type I interferons (IFN-I)—a group of cytokines with immunomodulatory, antiproliferative, and antiviral properties—are widely used as therapeutics for various cancers and viral diseases. Since IFNs are protein...

    Authors: Irina Rostovsky, Uri Wieler, Alona Kuzmina, Ran Taube and Neta Sal-Man
    Citation: Microbial Cell Factories 2024 23:163
  19. Wastewater treatment plants contribute approximately 6% of anthropogenic methane emissions. Methanotrophs, capable of converting methane into polyhydroxybutyrate (PHB), offer a promising solution for utilizing...

    Authors: Hyerim Eam, Dayoung Ko, Changsoo Lee and Jaewook Myung
    Citation: Microbial Cell Factories 2024 23:160
  20. Bacillus subtilis is widely used in industrial-scale riboflavin production. Previous studies have shown that targeted mutagenesis of the ribulose 5-phosphate 3-epimerase in B. subtilis can significantly enhance r...

    Authors: Chuan Liu, Miaomiao Xia, Huan Fang, Fan Xu, Sijia Wang and Dawei Zhang
    Citation: Microbial Cell Factories 2024 23:159
  21. This study explores the biosynthesis, characteristics, and functional properties of exopolysaccharide produced by the strain Liquorilactobacillus mali T6-52. The strain demonstrated significant EPS production wit...

    Authors: Manyu Wu, Shadi Pakroo, Chiara Nadai, Zeno Molinelli, Immacolata Speciale, Crisitina De Castro, Armin Tarrah, Jijin Yang, Alessio Giacomini and Viviana Corich
    Citation: Microbial Cell Factories 2024 23:158
  22. This study aimed to investigate the operation of three parallel biotrickling filters (BTFs) in removing H2S at different pH conditions (haloalkaliphilic, neutrophilic, and acidophilic) and their associated microb...

    Authors: Abbas Abbas Rouhollahi, Minoo Giyahchi, Seyed Mohammad Mehdi Dastgheib and Hamid Moghimi
    Citation: Microbial Cell Factories 2024 23:157
  23. Biosynthesis of metallic nanoparticles using microorganisms are a fabulous and emerging eco-friendly science with well-defined sizes, shapes and controlled monodispersity. Copper nanoparticles, among other met...

    Authors: Nahla M. Abdel Aziz, Doaa A. Goda, Dina I. Abdel-Meguid, Ebaa E. EL-Sharouny and Nadia A. Soliman
    Citation: Microbial Cell Factories 2024 23:156
  24. Rhizomucor miehei (RM) lipase is a regioselective lipase widely used in food, pharmaceutical and biofuel industries. However, the high cost and low purity of the commercial RM lipase limit its industrial applicat...

    Authors: Mingjun Yang, Xianhui Su, Jun Yang, Zhiwen Lu, Jie Zhou, Fei Wang, Yang Liu, Lixin Ma and Chao Zhai
    Citation: Microbial Cell Factories 2024 23:155
  25. Microbial cell factories serve as pivotal platforms for the production of high-value natural products, which tend to accumulate on the cell membrane due to their hydrophobic properties. However, the limited sp...

    Authors: Tao Wu, Jingjing Jiang, Hongyang Zhang, Jiazhi Liu and Haihua Ruan
    Citation: Microbial Cell Factories 2024 23:154
  26. Dihydroxyacetone (DHA) stands as a crucial chemical material extensively utilized in the cosmetics industry. DHA production through the dephosphorylation of dihydroxyacetone phosphate, an intermediate product ...

    Authors: Kaibo Zhang, Mengying Li, Jinsheng Wang, Guozhong Huang, Kang Ma, Jiani Peng, Haoyue Lin, Chunjie Zhang, Honglei Wang, Tao Zhan, Zhe Sun and Xueli Zhang
    Citation: Microbial Cell Factories 2024 23:153
  27. A novel plasmid-mediated resistance–nodulation–division (RND) efflux pump gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of convenient therapeutic options in the post-antibiot...

    Authors: Jindian Yang#, Lei Xu#, Yonglin Zhou, Minhe Cui, Dejun Liu, Jianfeng Wang, Yang Wang and Xuming Deng
    Citation: Microbial Cell Factories 2024 23:152
  28. Xylans are polysaccharides that are naturally abundant in agricultural by-products, such as cereal brans and straws. Microbial degradation of arabinoxylan is facilitated by extracellular esterases that remove ...

    Authors: Nian Liu, Elise Odinot, Hélène David, Nicolas Vita, Felipe Mejia Otalvaro, Goetz Parsiegla, Yann Denis, Craig Faulds, Henri-Pierre Fierobe and Stéphanie Perret
    Citation: Microbial Cell Factories 2024 23:151
  29. Azo dyes represent a common textile dye preferred for its high stability on fabrics in various harsh conditions. Although these dyes pose high-risk levels for all biological forms, fungal laccase is known as a...

    Authors: Amira Saad Abd El-latif, Abdel-Naser A. Zohri, Hamdy M. El-Aref and Ghada Abd-Elmonsef Mahmoud
    Citation: Microbial Cell Factories 2024 23:150
  30. Streptomyces is renowned for its robust biosynthetic capacity in producing medically relevant natural products. However, the majority of natural products biosynthetic gene clusters (BGCs) either yield low amounts...

    Authors: Evaldas Klumbys, Wei Xu, Lokanand Koduru, Elena Heng, Yifeng Wei, Fong Tian Wong, Huimin Zhao and Ee Lui Ang
    Citation: Microbial Cell Factories 2024 23:149
  31. The continuous progress in nanotechnology is rapid and extensive with overwhelming futuristic aspects. Through modernizing inventive synthesis protocols, a paradigm leapfrogging in novelties and findings are c...

    Authors: Asmaa G. Almahdy, Ahmed El-Sayed and Marwa Eltarahony
    Citation: Microbial Cell Factories 2024 23:148
  32. Aminopyrrolnitrin (APRN), a natural halogenated phenylpyrrole derivative (HPD), has strong antifungal and antiparasitic activities. Additionally, it showed 2.8-fold increased photostability compared to pyrroln...

    Authors: Virginia Ryandini Melati Putri, Min-Hee Jung, Ji-Young Lee, Mi-Hyang Kwak, Theavita Chatarina Mariyes, Anastasia Kerbs, Volker F. Wendisch, Hee Jeong Kong, Young-Ok Kim and Jin-Ho Lee
    Citation: Microbial Cell Factories 2024 23:147
  33. Cellobiose dehydrogenase (CDH) is an extracellular fungal oxidoreductase with multiple functions in plant biomass degradation. Its primary function as an auxiliary enzyme of lytic polysaccharide monooxygenase ...

    Authors: Angela Giorgianni, Alice Zenone, Leander Sützl, Florian Csarman and Roland Ludwig
    Citation: Microbial Cell Factories 2024 23:146
  34. Recombinant multiepitope proteins (RMPs) are a promising alternative for application in diagnostic tests and, given their wide application in the most diverse diseases, this review article aims to survey the u...

    Authors: Ana Alice Maia Gonçalves, Anna Julia Ribeiro, Carlos Ananias Aparecido Resende, Carolina Alves Petit Couto, Isadora Braga Gandra, Isabelle Caroline dos Santos Barcelos, Jonatas Oliveira da Silva, Juliana Martins Machado, Kamila Alves Silva, Líria Souza Silva, Michelli dos Santos, Lucas da Silva Lopes, Mariana Teixeira de Faria, Sabrina Paula Pereira, Sandra Rodrigues Xavier, Matheus Motta Aragão…
    Citation: Microbial Cell Factories 2024 23:145
  35. Fengycin is an important member of the lipopeptide family with a wide range of applications in the agricultural, food, medical and cosmetic industries. However, its commercial applicatio...

    Authors: Ying Yin, Xin Wang, Pengsheng Zhang, Pan Wang and Jianping Wen
    Citation: Microbial Cell Factories 2024 23:144
  36. The Porcine epidemic diarrhea virus (PEDV) presents a substantial risk to the domestic pig industry, resulting in extensive and fatal viral diarrhea among piglets. Recognizing the mucosal stimulation triggered...

    Authors: Bin Zhang, Hongchao Gou, Haiyan Shen, Chunhong Zhang, Zhicheng Liu, Nile Wuri, Jingjing Nie, Yunzhi Qu, Jianfeng Zhang and Letu Geri
    Citation: Microbial Cell Factories 2024 23:142
  37. The oleaginous yeast Rhodotorula toruloides is a promising chassis organism for the biomanufacturing of value-added bioproducts. It can accumulate lipids at a high fraction of biomass. However, metabolic engineer...

    Authors: Shekhar Mishra, Anshu Deewan, Huimin Zhao and Christopher V. Rao
    Citation: Microbial Cell Factories 2024 23:141
  38. Quantum Dots (QDs) are fluorescent nanoparticles with exceptional optical and optoelectronic properties, finding widespread utility in diverse industrial applications. Presently, chemically synthesized QDs are...

    Authors: Matías Vargas-Reyes, Nicolás Bruna, Javiera Ramos-Zúñiga, Felipe Valenzuela-Ibaceta, Paula Rivas-Álvarez, Claudio A. Navarro and José M. Pérez-Donoso
    Citation: Microbial Cell Factories 2024 23:140
  39. Genome-scale metabolic models (GEMs) serve as effective tools for understanding cellular phenotypes and predicting engineering targets in the development of industrial strain. Enzyme-constrained genome-scale m...

    Authors: Yutao Wang, Zhitao Mao, Jiacheng Dong, Peiji Zhang, Qiang Gao, Defei Liu, Chaoguang Tian and Hongwu Ma
    Citation: Microbial Cell Factories 2024 23:138
  40. Microbial engineering aims to enhance the ability of bacteria to produce valuable products, including vitamin B6 for various applications. Numerous microorganisms naturally produce vitamin B6, yet the metabolic p...

    Authors: Zhizhong Tian, Linxia Liu, Lijuan Wu, Zixuan Yang, Yahui Zhang, Liping Du and Dawei Zhang
    Citation: Microbial Cell Factories 2024 23:137
  41. Biotin, serving as a coenzyme in carboxylation reactions, is a vital nutrient crucial for the natural growth, development, and overall well-being of both humans and animals. Consequently, biotin is widely util...

    Authors: Donghan Ma, Guangqing Du, Huan Fang, Rong Li and Dawei Zhang
    Citation: Microbial Cell Factories 2024 23:135
  42. Lovastatin has widespread applications thanks to its multiple pharmacological effects. Fermentation by filamentous fungi represents the major way of lovastatin production. However, the current lovastatin produ...

    Authors: Han Na, Yao-yao Zheng, Yaoning Jia, Jingzhao Feng, Jizi Huang, Jihao Huang, Chang-Yun Wang and Guangshan Yao
    Citation: Microbial Cell Factories 2024 23:134
  43. Mycosporine-like amino acids (MAAs) are a class of strongly UV-absorbing compounds produced by cyanobacteria, algae and corals and are promising candidates for natural sunscreen components. Low MAA yields from...

    Authors: Miselle Tiana Hengardi, Cui Liang, Keshiniy Madivannan, Lay Kien Yang, Lokanand Koduru, Yoganathan Kanagasundaram and Prakash Arumugam
    Citation: Microbial Cell Factories 2024 23:121

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