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Microbial Cell Factories


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  1. Content type: RESEARCH

    Chinese Nong-flavor (NF) liquor is continuously and stably produced by solid-state fermentation technology for 1000 years, resulting in enrichment of special microbial community and enzymes system in its start...

    Authors: Zhuolin Yi, Yang Fang, Kaize He, Dayu Liu, Huibo Luo, Dong Zhao, Hui He, Yanling Jin and Hai Zhao

    Citation: Microbial Cell Factories 2018 17:30

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  2. Content type: RESEARCH

    The direct link between inflammatory bowel diseases and colorectal cancer is well documented. Previous studies have reported that some lactic acid bacterial strains could inhibit colon cancer progression howev...

    Authors: Nehal M. El-Deeb, Abdelrahman M. Yassin, Lamiaa A. Al-Madboly and Amr El-Hawiet

    Citation: Microbial Cell Factories 2018 17:29

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  3. Content type: RESEARCH

    Inorganic polyphosphate bodies (PPB) have recently been linked to a variety of functions in mammalian cells. To improve the yield of PPB from Synechococcus sp. PCC 7002 and characterize its form, in this study, a...

    Authors: Fengzheng Gao, Haohao Wu, Mingyong Zeng, Min Huang and Guangxin Feng

    Citation: Microbial Cell Factories 2018 17:27

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  4. Content type: RESEARCH

    The deep-sea-derived microbe Streptomyces koyangensis SCSIO 5802 produces neoabyssomicins A–B (12) and abyssomicins 2 (3) and 4 (4). Neoabyssomicin A (1) augments human immunodeficiency virus-1 (HIV-1) replicati...

    Authors: Jiajia Tu, Siting Li, Jiang Chen, Yongxiang Song, Shaobin Fu, Jianhua Ju and Qinglian Li

    Citation: Microbial Cell Factories 2018 17:28

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  5. Content type: RESEARCH

    Genome sequencing revealed that Streptomyces sp. can dedicate up to ~ 10% of their genomes for the biosynthesis of bioactive secondary metabolites. However, the majority of these biosynthetic gene clusters are on...

    Authors: Dimitris Kallifidas, Guangde Jiang, Yousong Ding and Hendrik Luesch

    Citation: Microbial Cell Factories 2018 17:25

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  6. Content type: RESEARCH

    Dengue is listed as a neglected tropical disease by the Center for Disease Control and Preservation, as there are insufficient integrated surveillance strategies, no effective treatment, and limited licensed v...

    Authors: Jyotiranjan Bal, Nguyen Ngoc Luong, Jisang Park, Ki-Duk Song, Yong-Suk Jang and Dae-Hyuk Kim

    Citation: Microbial Cell Factories 2018 17:24

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  7. Content type: RESEARCH

    Kojibiose as a prebiotic and inhibitor of α-glucosidase exhibits potential for a wide range of applications in the food and medicine fields; however, large-scale separation and extraction of kojibiose from nat...

    Authors: Miaomiao Wang, Jing Wu and Dan Wu

    Citation: Microbial Cell Factories 2018 17:23

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  8. Content type: RESEARCH

    Lactobacillus casei is widely used in the dairy and pharmaceutical industries and a promising candidate for use as cell factories. Recently, genome sequencing and functional genomics provide the possibility for r...

    Authors: Yongping Xin, Tingting Guo, Yingli Mu and Jian Kong

    Citation: Microbial Cell Factories 2018 17:21

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  9. Content type: RESEARCH

    Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV) has led to serious economic losses to the swine industry worldwide. In this study, an oral recombinant Lactobacillus casei vaccine agains...

    Authors: Sunting Ma, Li Wang, Xuewei Huang, Xiaona Wang, Su Chen, Wen Shi, Xinyuan Qiao, Yanping Jiang, Lijie Tang, Yigang Xu and Yijing Li

    Citation: Microbial Cell Factories 2018 17:20

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  10. Content type: RESEARCH

    Fatty aldehydes are industrially relevant compounds, which also represent a common metabolic intermediate in the microbial synthesis of various oleochemicals, including alkanes, fatty alcohols and wax esters. ...

    Authors: Tapio Lehtinen, Elena Efimova, Suvi Santala and Ville Santala

    Citation: Microbial Cell Factories 2018 17:19

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  11. Content type: Research

    Antibiotic residues can cause antibiotic resistance in livestock and their food safety-related issues have increased the consumer demand for products lacking these residues. Hence, developing safe and effectiv...

    Authors: Min Zhang, Yuanlong Shan, Hongtao Gao, Bin Wang, Xin Liu, Yuanyuan Dong, Xiuming Liu, Na Yao, Yonggang Zhou, Xiaowei Li and Haiyan Li

    Citation: Microbial Cell Factories 2018 17:18

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  12. Content type: RESEARCH

    Chimeric virus-like particles (VLP) allow the display of foreign antigens on their surface and have proved valuable in the development of safe subunit vaccines or drug delivery. However, finding an inexpensive...

    Authors: David Wetzel, Theresa Rolf, Manfred Suckow, Andreas Kranz, Andreas Barbian, Jo-Anne Chan, Joachim Leitsch, Michael Weniger, Volker Jenzelewski, Betty Kouskousis, Catherine Palmer, James G. Beeson, Gerhard Schembecker, Juliane Merz and Michael Piontek

    Citation: Microbial Cell Factories 2018 17:17

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  13. Content type: RESEARCH

    The deep-sea environment harbors a vast pool of novel enzymes. Owing to the limitations of cultivation, cultivation-independent has become an effective method for mining novel enzymes from the environment. Bas...

    Authors: Ying-Yi Huo, Shu-Ling Jian, Hong Cheng, Zhen Rong, Heng-Lin Cui and Xue-Wei Xu

    Citation: Microbial Cell Factories 2018 17:16

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  14. Content type: RESEARCH

    The CRISPR/dCas9 system is a powerful tool to activate the transcription of target genes in eukaryotic or prokaryotic cells, but lacks assays in complex conditions, such as the biosynthesis of secondary metabo...

    Authors: Ran Peng, Ye Wang, Wan-wan Feng, Xin-jing Yue, Jiang-he Chen, Xiao-zhuang Hu, Zhi-feng Li, Duo-hong Sheng, You-ming Zhang and Yue-zhong Li

    Citation: Microbial Cell Factories 2018 17:15

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  15. Content type: Research

    Due to the important role of rifamycin in curing tuberculosis infection, the study on rifamycin has never been stopped. Although RifZ, which locates within the rifamycin biosynthetic cluster, has recently been...

    Authors: Chao Lei, Jingzhi Wang, Yuanyuan Liu, Xinqiang Liu, Guoping Zhao and Jin Wang

    Citation: Microbial Cell Factories 2018 17:14

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  16. Content type: RESEARCH

    The conjugative plasmid, pLS20, isolated from Bacillus subtilis natto, has an outstanding capacity for rapid self-transfer. In addition, it can function as a helper plasmid, mediating the mobilization of an indep...

    Authors: Megumi Miyano, Kosei Tanaka, Shu Ishikawa, Shinji Takenaka, Andrés Miguel-Arribas, Wilfried J. J. Meijer and Ken-ichi Yoshida

    Citation: Microbial Cell Factories 2018 17:13

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  17. Content type: RESEARCH

    Cocoa butter (CB) extracted from cocoa beans (Theobroma cacao) is the main raw material for chocolate production, but CB supply is insufficient due to the increased chocolate demand and limited CB production. CB ...

    Authors: Yongjun Wei, David Bergenholm, Michael Gossing, Verena Siewers and Jens Nielsen

    Citation: Microbial Cell Factories 2018 17:11

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  18. Content type: RESEARCH

    Synthetic organism-based biotechnologies are increasingly being proposed for environmental applications, such as in situ sensing. Typically, the novel function of these organisms is delivered by compiling gene...

    Authors: Jillian M. Couto, Anne McGarrity, Julie Russell and William T. Sloan

    Citation: Microbial Cell Factories 2018 17:8

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  19. Content type: RESEARCH

    Azotobacter vinelandii is a bacterium that produces alginate and polyhydroxybutyrate (P3HB); however, the role of NAD(P)H/NAD(P)+ ratios on the metabolic fluxes through biosynthesis pathways of these biopolymers ...

    Authors: Andres García, Pau Ferrer, Joan Albiol, Tania Castillo, Daniel Segura and Carlos Peña

    Citation: Microbial Cell Factories 2018 17:10

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  20. Content type: RESEARCH

    Pseudomonas chlororaphis HT66 isolated from the rice rhizosphere is an important plant growth-promoting rhizobacteria that produce phenazine-1-carboxamide (PCN) in high yield. Phenazine production is regulated by...

    Authors: Huasong Peng, Yi Ouyang, Muhammad Bilal, Wei Wang, Hongbo Hu and Xuehong Zhang

    Citation: Microbial Cell Factories 2018 17:9

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  21. Content type: Research

    Dunaliella salina is a unicellular green alga with a high α-linolenic acid (ALA) level, but a low eicosapentaenoic acid (EPA) level. In a previous analysis of the catalytic activity of delta 6 fatty acid desatura...

    Authors: Haisu Shi, Xue Luo, Rina Wu and Xiqing Yue

    Citation: Microbial Cell Factories 2018 17:7

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  22. Content type: Research

    The thorough understanding of the physiological and pathological processes mediated by extracellular vesicles (EVs) is challenged by purification methods which are cumbersome, not reproducible, or insufficient...

    Authors: Milica Popovic, Elisa Mazzega, Barbara Toffoletto and Ario de Marco

    Citation: Microbial Cell Factories 2018 17:6

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