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  1. Content type: RESEARCH

    Polyene antibiotics are important as antifungal medicines albeit with serious side effects such as nephrotoxicity. Reedsmycin (RDM) A (1), produced by marine-derived Streptomyces youssoufiensis OUC6819, is a non-...

    Authors: Tingting Yao, Zengzhi Liu, Tong Li, Hui Zhang, Jing Liu, Huayue Li, Qian Che, Tianjiao Zhu, Dehai Li and Wenli Li

    Citation: Microbial Cell Factories 2018 17:98

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  2. Content type: Review

    The goal of this research is the investigation of a way to maximize the production of docosahexaenoic acid (DHA) and β-carotene by optimizing the culture conditions of their sources, microalgae Schizochytrium lim...

    Authors: Maria Bindea, Bogdan Rusu, Alexandru Rusu, Monica Trif, Loredana Florina Leopold, Francisc Dulf and Dan Cristian Vodnar

    Citation: Microbial Cell Factories 2018 17:97

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  3. Content type: RESEARCH

    The cellulolytic fungus Neurospora crassa is considered a potential host for enzyme and bioethanol production. However, large scale applications are hindered by its filamentous growth. Although previous investiga...

    Authors: Liangcai Lin, Zhiyong Sun, Jingen Li, Yong Chen, Qian Liu, Wenliang Sun and Chaoguang Tian

    Citation: Microbial Cell Factories 2018 17:96

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  4. Content type: RESEARCH

    The lifestyle of filamentous fungi depends on the secretion of hydrolytic enzymes into the surrounding medium, which degrade polymeric substances into monomers that are then taken up to sustain metabolism. Thi...

    Authors: Markus R. M. Fiedler, Lars Barthel, Christin Kubisch, Corrado Nai and Vera Meyer

    Citation: Microbial Cell Factories 2018 17:95

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  5. Content type: RESEARCH

    α-d-Glucosylglycerol (αGG) has beneficial functions as a moisturizing agent in cosmetics and potential as a health food material, and therapeutic agent. αGG serves as compatible solute in various halotolerant cya...

    Authors: Benjamin Roenneke, Natalie Rosenfeldt, Sami M. Derya, Jens F. Novak, Kay Marin, Reinhard Krämer and Gerd M. Seibold

    Citation: Microbial Cell Factories 2018 17:94

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  6. Content type: RESEARCH

    Co-production of polyhydroxyalkanoate (PHA) and amino acids makes bacteria effective microbial cell factories by secreting amino acids outside while accumulating PHA granules inside. Poly(3-hydroxybutyrate-co-...

    Authors: Wenjian Ma, Jianli Wang, Ye Li, Lianghong Yin and Xiaoyuan Wang

    Citation: Microbial Cell Factories 2018 17:93

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  7. Content type: RESEARCH

    1,3-Propanediol (1,3-PDO) is important building blocks for the bio-based chemical industry, Klebsiella pneumoniae can be an attractive candidate for their production. However, 1,3-PDO production is high but produ...

    Authors: Baek-Rock Oh, Sung-Mok Lee, Sun-Yeon Heo, Jeong-Woo Seo and Chul Ho Kim

    Citation: Microbial Cell Factories 2018 17:92

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  8. Content type: RESEARCH

    A future bioeconomy relies on the development of technologies to convert waste into valuable compounds. We present here an attempt to design a biotechnological cascade for the conversion of vegetable waste int...

    Authors: Annemarie Schmidt, Gunnar Sturm, Christian Jonas Lapp, Daniel Siebert, Florencia Saravia, Harald Horn, Padma Priya Ravi, Andreas Lemmer and Johannes Gescher

    Citation: Microbial Cell Factories 2018 17:90

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  9. Content type: RESEARCH

    ʟ-Ornithine is an important amino acid with broad applications in pharmaceutical and food industries. Despite lagging ʟ-ornithine productivity and cost reduction, microbial fermentation is a promising route fo...

    Authors: Bin Zhang, Miao Yu, Wen-Ping Wei and Bang-Ce Ye

    Citation: Microbial Cell Factories 2018 17:91

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  10. Content type: RESEARCH

    Some marine bacteria, such as Moritella marina, produce the nutraceutical docosahexaenoic acid (DHA) thanks to a specific enzymatic complex called Pfa synthase. Escherichia coli heterologously expressing the pfa ...

    Authors: Laura Giner-Robles, Beatriz Lázaro, Fernando de la Cruz and Gabriel Moncalián

    Citation: Microbial Cell Factories 2018 17:88

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  11. Content type: Research

    Cephalosporin C (CPC) produced by Acremonium chrysogenum is one of the most important drugs for treatment of bacterial infectious diseases. As the major stimulant, methionine is widely used in the industrial prod...

    Authors: Jiajia Liu, Wenyan Gao, Yuanyuan Pan and Gang Liu

    Citation: Microbial Cell Factories 2018 17:87

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  12. Content type: Correction

    Upon publication of this article [1], it was brought to our attention that Figs. 3, 4 and 5 are incorrectly presented in the original version of the article. The figures were inadvertently swapped in the origi...

    Authors: Zothanpuia, Ajit Kumar Passari, Vincent Vineeth Leo, Preeti Chandra, Brijesh Kumar, Chandra Nayak, Abeer Hashem, Elsayed Fathi Abd_Allah, Abdulaziz A. Alqarawi and Bhim Pratap Singh

    Citation: Microbial Cell Factories 2018 17:86

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    The original article was published in Microbial Cell Factories 2018 17:68

  13. Content type: RESEARCH

    Geranyl acetate is widely used in the fragrance and cosmetic industries, and thus has great economic value. However, plants naturally produce a mixture of hundreds of esters, and geranyl acetate is usually onl...

    Authors: Tao Wu, Siwei Li, Bolin Zhang, Changhao Bi and Xueli Zhang

    Citation: Microbial Cell Factories 2018 17:85

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  14. Content type: RESEARCH

    Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is available on the combinatorial biosynthesis strategies appl...

    Authors: Ling Gao, Jianping Guo, Yun Fan, Zhi Ma, Zhaoxin Lu, Chong Zhang, Haizhen Zhao and Xiaomei Bie

    Citation: Microbial Cell Factories 2018 17:84

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  15. Content type: RESEARCH

    Saccharomyces cerevisiae is a host for the industrial production of S-adenosyl-l-methionine (SAM), which has been widely used in pharmaceutical and nutritional supplement industries. It has been reported that the...

    Authors: Kenshi Hayakawa, Fumio Matsuda and Hiroshi Shimizu

    Citation: Microbial Cell Factories 2018 17:82

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  16. Content type: RESEARCH

    Water stress is a critical issue for plant growth in arid sandy soils. Here, we aimed to select bacteria producing polyextremotolerant surface-active compounds capable of improving water retention and humidity...

    Authors: Noura Raddadi, Lucia Giacomucci, Ramona Marasco, Daniele Daffonchio, Ameur Cherif and Fabio Fava

    Citation: Microbial Cell Factories 2018 17:83

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  17. Content type: RESEARCH

    Utilization of cocoa pod husks (CPH) in animal feed is hindered by the presence of theobromine, which is variably toxic to animals. Treatment of this agro-waste to remove theobromine, while preserving its nutr...

    Authors: Daniel Oduro-Mensah, Augustine Ocloo, Sammy T. Lowor, Cheetham Mingle, Laud K. N.-A. Okine and Naa Ayikailey Adamafio

    Citation: Microbial Cell Factories 2018 17:79

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  18. Content type: RESEARCH

    2-Keto-l-gulonic acid (2-KGA), the precursor of vitamin C, is currently produced by two-step fermentation. In the second step, l-sorbose is transformed into 2-KGA by the symbiosis system composed of Ketogulonicig...

    Authors: Cai-Yun Wang, Ye Li, Zi-Wei Gao, Li-Cheng Liu, Meng-Yue Zhang, Tian-Yuan Zhang, Chun-Fu Wu and Yi-Xuan Zhang

    Citation: Microbial Cell Factories 2018 17:81

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  19. Content type: RESEARCH

    Gamma-aminobutyric acid (GABA) plays a significant role in the food and drug industries. Our previous study established an efficient fed-batch fermentation process for Lactobacillus brevis NCL912 production of GA...

    Authors: Qiong Wang, Xiaohua Liu, Jinheng Fu, Shuixing Wang, Yuanhong Chen, Kunpeng Chang and Haixing Li

    Citation: Microbial Cell Factories 2018 17:80

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  20. Content type: RESEARCH

    3-Ketosteroid-Δ1-dehydrogenase (KstD) is a key enzyme in the metabolic pathway for chemical modifications of steroid hormones. Only a few KstDs have thus far been characterized biochemically and applied for th...

    Authors: Ruijie Zhang, Xiangcen Liu, Yushi Wang, Yuchang Han, Junsong Sun, Jiping Shi and Baoguo Zhang

    Citation: Microbial Cell Factories 2018 17:77

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  21. Content type: RESEARCH

    The characterization of the molecular determinants of metal resistance has potential biotechnological application in biosensing and bioremediation. In this context, the bacterium Thermus thermophilus HB27 is a me...

    Authors: Immacolata Antonucci, Giovanni Gallo, Danila Limauro, Patrizia Contursi, Ana Luisa Ribeiro, Alba Blesa, José Berenguer, Simonetta Bartolucci and Gabriella Fiorentino

    Citation: Microbial Cell Factories 2018 17:78

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  22. Content type: RESEARCH

    Cellulase can convert lignocellulosic feedstocks into fermentable sugars, which can be used for the industrial production of biofuels and chemicals. The high cost of cellulase production remains a challenge fo...

    Authors: Jiajia Zhang, Guoxiu Zhang, Wei Wang, Wei Wang and Dongzhi Wei

    Citation: Microbial Cell Factories 2018 17:75

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  23. Content type: RESEARCH

    l-Arabinose is the second most abundant component of hemicellulose in lignocellulosic biomass, next to d-xylose. However, few microorganisms are capable of utilizing pentoses, and catabolic genes and operons enab...

    Authors: Hideo Kawaguchi, Kumiko Yoshihara, Kiyotaka Y. Hara, Tomohisa Hasunuma, Chiaki Ogino and Akihiko Kondo

    Citation: Microbial Cell Factories 2018 17:76

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  24. Content type: RESEARCH

    Despite its ability to grow and produce high-value molecules using renewable carbon sources, two main factors must be improved to use Burkholderia sacchari as a chassis for bioproduction at an industrial scale: f...

    Authors: Linda P. Guamán, Carlos Barba-Ostria, Fuzhong Zhang, Edmar R. Oliveira-Filho, José Gregório C. Gomez and Luiziana F. Silva

    Citation: Microbial Cell Factories 2018 17:74

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