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  1. Content type: RESEARCH

    The oleaginous yeast Yarrowia lipolytica is a promising microbial cell factory due to their biochemical characteristics and native capacity to accumulate lipid-based chemicals. To create heterogenous biosynthesis...

    Authors: Jin-lai Zhang, Yang-Zi Peng, Duo Liu, Hong Liu, Ying-Xiu Cao, Bing-Zhi Li, Chun Li and Ying-Jin Yuan

    Citation: Microbial Cell Factories 2018 17:62

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  2. Content type: RESEARCH

    Type III polyketide synthases (PKSs) are simple homodimer ketosynthases that distribute across plants, fungi, and bacteria, catalyzing formation of pyrone- and resorcinol-types aromatic polyketides with variou...

    Authors: Lukuan Hou, Huiming Huang, Huayue Li, Shuyao Wang, Jianhua Ju and Wenli Li

    Citation: Microbial Cell Factories 2018 17:61

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  3. Content type: RESEARCH

    Saccharomyces cerevisiae, engineered for l-lactic acid production from glucose and xylose, is a promising production host for lignocellulose-to-lactic acid processes. However, the two principal engineering strate...

    Authors: Vera Novy, Bernd Brunner and Bernd Nidetzky

    Citation: Microbial Cell Factories 2018 17:59

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  4. Content type: RESEARCH

    2-phenylethanol (2-PE) is an important aromatic compound with a lovely rose-like scent. Saccharomyces cerevisiae is a desirable microbe for 2-PE production but its natural yield is not high, and one or two crucia...

    Authors: Zhaoyue Wang, Mingyue Jiang, Xuena Guo, Zhaozheng Liu and Xiuping He

    Citation: Microbial Cell Factories 2018 17:60

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  5. Content type: RESEARCH

    Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve production efficiency under industrially relevant conditions, coordinated expression of multiple genes by manipul...

    Authors: Liang Xiong, Yu Zeng, Rui-Qi Tang, Hal S. Alper, Feng-Wu Bai and Xin-Qing Zhao

    Citation: Microbial Cell Factories 2018 17:58

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  6. Content type: RESEARCH

    AmbLOXe is a lipoxygenase, which is up-regulated during limb-redevelopment in the Mexican axolotl, Ambystoma mexicanum, an animal with remarkable regeneration capacity. Previous studies have shown that mammalian ...

    Authors: Anne Stamm, Sarah Strauß, Peter Vogt, Thomas Scheper and Iliyana Pepelanova

    Citation: Microbial Cell Factories 2018 17:57

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  7. Content type: RESEARCH

    Klebsiella pneumoniae is a promising industrial species for bioproduction of bulk chemicals such as 1,3-propanediol, 2,3-butanediol and 3-hydroxypropionic acid (3-HP). However, lactic acid is a troublesome by-pro...

    Authors: Jingxuan Wang, Peng Zhao, Ying Li, Lida Xu and Pingfang Tian

    Citation: Microbial Cell Factories 2018 17:56

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  8. Content type: RESEARCH

    The production of recombinant proteins with proper conformation, appropriate post-translational modifications in an easily scalable and cost-effective system is challenging. Lactococcus lactis has recently been i...

    Authors: Susheel K. Singh, Régis Wendpayangde Tiendrebeogo, Bishwanath Kumar Chourasia, Ikhlaq Hussain Kana, Subhash Singh and Michael Theisen

    Citation: Microbial Cell Factories 2018 17:55

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  9. Content type: RESEARCH

    Microalgal metabolic engineering holds great promise for the overproduction of a wide range of commercial bioproducts. It demands simultaneous manipulation of multiple metabolic nodes. However, high-efficiency...

    Authors: Li-Gong Zou, Jia-Wen Chen, Dan-Lin Zheng, Srinivasan Balamurugan, Da-Wei Li, Wei-Dong Yang, Jie-Sheng Liu and Hong-Ye Li

    Citation: Microbial Cell Factories 2018 17:54

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  10. Content type: RESEARCH

    Growth conditions that bring about stress on Phaffia rhodozyma cells encourage the synthesis of astaxanthin, an antioxidant carotenoid, which protects cells against oxidative damage. Using P. rhodozyma cultures p...

    Authors: Anahí Martínez-Cárdenas, Cipriano Chávez-Cabrera, Jazmín M. Vasquez-Bahena and Luis B. Flores-Cotera

    Citation: Microbial Cell Factories 2018 17:53

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  11. Content type: RESEARCH

    Thermostable lipases from microbial sources have been substantially overexpressed in E. coli, however, these enzymes are often produced with low-level enzymatic activity and mainly in the form of inclusion bodies...

    Authors: Weiqing Zhang, Jing Lu, Shuwen Zhang, Lu Liu, Xiaoyang Pang and Jiaping Lv

    Citation: Microbial Cell Factories 2018 17:50

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  12. Content type: Review

    Torulene and torularhodin represent the group of carotenoids and are synthesized by yeasts and fungi. The most important producers of these two compounds include yeasts of Rhodotorula and Sporobolomyces genera. T...

    Authors: Anna M. Kot, Stanisław Błażejak, Iwona Gientka, Marek Kieliszek and Joanna Bryś

    Citation: Microbial Cell Factories 2018 17:49

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  13. Content type: RESEARCH

    The unicellular cyanobacterium Synechocystis sp. PCC 6803 has been widely used as a photoautotrophic host for synthetic biology studies. However, as a green chassis to capture CO2 for biotechnological application...

    Authors: Deng Liu and Himadri B. Pakrasi

    Citation: Microbial Cell Factories 2018 17:48

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  14. Content type: RESEARCH

    Chitinases are ubiquitous enzymes that have gained a recent biotechnological attention due to their ability to transform biological waste from chitin into valued chito-oligomers with wide agricultural, industr...

    Authors: Peter Elias Kidibule, Paloma Santos-Moriano, Elena Jiménez-Ortega, Mercedes Ramírez-Escudero, M. Carmen Limón, Miguel Remacha, Francisco José Plou, Julia Sanz-Aparicio and María Fernández-Lobato

    Citation: Microbial Cell Factories 2018 17:47

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  15. Content type: RESEARCH

    Hydroxycinnamoyl anthranilates, also known as avenanthramides (avns), are a group of phenolic alkaloids with anti-inflammatory, antioxidant, anti-itch, anti-irritant, and antiatherogenic activities. Some avena...

    Authors: Su Jin Lee, Geun Young Sim, Hyunook Kang, Won Seok Yeo, Bong-Gyu Kim and Joong-Hoon Ahn

    Citation: Microbial Cell Factories 2018 17:46

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  16. Content type: RESEARCH

    In industries lipolytic reactions occur in insensitive conditions such as high temperature thus novel stout esterases with unique properties are attracts to the industrial application. Protein engineering is t...

    Authors: Haofeng Gao, Chanjuan Li, Ramesh Bandikari, Ziduo Liu, Nan Hu and Qiang Yong

    Citation: Microbial Cell Factories 2018 17:45

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  17. Content type: RESEARCH

    Biodegradation of hydrocarbons in Antarctic soil has been reported to be achieved through the utilisation of indigenous cold-adapted microorganisms. Although numerous bacteria isolated from hydrocarbon-contami...

    Authors: Syahir Habib, Siti Aqlima Ahmad, Wan Lutfi Wan Johari, Mohd Yunus Abd Shukor, Siti Aisyah Alias, Khalilah Abdul Khalil and Nur Adeela Yasid

    Citation: Microbial Cell Factories 2018 17:44

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  18. Content type: RESEARCH

    In the l-histidine (His) biosynthetic pathway of Escherichia coli, the first key enzyme, ATP-phosphoribosyltransferase (ATP-PRT, HisG), is subject to different types of inhibition. Eliminating the feedback inhibi...

    Authors: Evgeniya A. Malykh, Ivan A. Butov, Anna B. Ravcheeva, Alexander A. Krylov, Sergey V. Mashko and Nataliya V. Stoynova

    Citation: Microbial Cell Factories 2018 17:42

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  19. Content type: RESEARCH

    Members of the genus Streptomyces are Gram-positive bacteria that are used as important cell factories to produce secondary metabolites and secrete heterologous proteins. They possess some of the largest bacteria...

    Authors: Konstantinos C. Tsolis, Evridiki-Pandora Tsare, Georgia Orfanoudaki, Tobias Busche, Katerina Kanaki, Reshmi Ramakrishnan, Frederic Rousseau, Joost Schymkowitz, Christian Rückert, Jörn Kalinowski, Jozef Anné, Spyridoula Karamanou, Maria I. Klapa and Anastassios Economou

    Citation: Microbial Cell Factories 2018 17:43

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  20. Content type: Research

    The soil bacterium Pseudomonas putida KT2440 is a “generally recognized as safe”-certified strain with robust property and versatile metabolism. Thus, it is an ideal candidate for synthetic biology, biodegradatio...

    Authors: Jun Sun, Qingzhuo Wang, Yu Jiang, Zhiqiang Wen, Lirong Yang, Jianping Wu and Sheng Yang

    Citation: Microbial Cell Factories 2018 17:41

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  21. Content type: RESEARCH

    To produce 1-propanol as a potential biofuel, metabolic engineering of microorganisms, such as E. coli, has been studied. However, 1-propanol production using metabolically engineered Saccharomyces cerevisiae, wh...

    Authors: Yuya Nishimura, Terumi Matsui, Jun Ishii and Akihiko Kondo

    Citation: Microbial Cell Factories 2018 17:38

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  22. Content type: RESEARCH

    Rhamnolipids are the most extensively studied biosurfactants and has been successfully used in various areas from bioremediation to industrial fields. Rhamnolipids structural composition decide their physicoch...

    Authors: Feng Zhao, Rongjiu Shi, Fang Ma, Siqin Han and Ying Zhang

    Citation: Microbial Cell Factories 2018 17:39

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