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  1. The genus Eubacterium is quite diverse and includes several acetogenic strains capable of fermenting C1-substrates into valuable products. Especially, Eubacterium limosum and closely related strains attract atten...

    Authors: Maximilian Flaiz, Anja Poehlein, Wiebke Wilhelm, Alexander Mook, Rolf Daniel, Peter Dürre and Frank R. Bengelsdorf
    Citation: Microbial Cell Factories 2024 23:24
  2. Melanin is a natural pigment that is considered a promising biomaterial for numerous biotechnological applications across several industries. Melanin has biomedical applications as antimicrobial, anticancer, a...

    Authors: Nessma A. El-Zawawy, El-Refaie Kenawy, Sara Ahmed and Shimaa El-Sapagh
    Citation: Microbial Cell Factories 2024 23:23
  3. Trichoderma reesei is an organism extensively used in the bioethanol industry, owing to its capability to produce enzymes capable of breaking down holocellulose into simple sugars. The uptake of carbohydrates gen...

    Authors: Karoline Maria Vieira Nogueira, Vanessa Mendes, Karthik Shantharam Kamath, Anusha Cheruku, Letícia Harumi Oshiquiri, Renato Graciano de Paula, Claudia Carraro, Wellington Ramos Pedersoli, Lucas Matheus Soares Pereira, Luiz Carlos Vieira, Andrei Stecca Steindorff, Ardeshir Amirkhani, Matthew J. McKay, Helena Nevalainen, Mark P. Molloy and Roberto N. Silva
    Citation: Microbial Cell Factories 2024 23:22
  4. Ralstonia eutropha H16, a facultative chemolitoautotroph, is an important workhorse for bioindustrial production of useful compounds such as polyhydroxyalkanoates (PHAs). Despite the extensive studies to date, so...

    Authors: Kai-Hee Huong, Izumi Orita and Toshiaki Fukui
    Citation: Microbial Cell Factories 2024 23:21
  5. The increasing interest in environmental protection laws has compelled companies to regulate the disposal of waste organic materials. Despite efforts to explore alternative energy sources, the world remains he...

    Authors: Ghada E. Hegazy, Nadia A. Soliman, Soha Farag, Ehab R. El-Helow, Hoda Y. Yusef and Yasser R. Abdel-Fattah
    Citation: Microbial Cell Factories 2024 23:20
  6. Utilization of commensal bacteria for delivery of medicinal proteins, such as vaccine antigens, is an emerging strategy. Here, we describe two novel food-grade strains of lactic acid bacteria, Lactiplantibacillus...

    Authors: Kamilla Wiull, Live Heldal Hagen, Jelena Rončević, Bjørge Westereng, Preben Boysen, Vincent G. H. Eijsink and Geir Mathiesen
    Citation: Microbial Cell Factories 2024 23:19
  7. Antibiotic-based plasmid selection and maintenance is a core tool in molecular biology; however, while convenient, this strategy has numerous drawbacks for biological manufacturing. Overuse of antibiotics and ...

    Authors: Katherine E. Brechun, Marion Förschle, Marlen Schmidt and Harald Kranz
    Citation: Microbial Cell Factories 2024 23:18
  8. Yeast treatment has been used for purification of fructooligosaccharides (FOSs). However, the main drawback of this approach is that yeast can only partially remove sucrose from crude FOSs. The main objective ...

    Authors: Jakkrit Aisara, Jirat Wongsanittayarak, Nalapat Leangnim, Kraikrit Utama, Padchanee Sangthong, Woraprapa Sriyotai, Sugunya Mahatheeranont, Suphat Phongthai, Kridsada Unban, Saisamorn Lumyong, Chartchai Khanongnuch, Pairote Wongputtisin and Apinun Kanpiengjai
    Citation: Microbial Cell Factories 2024 23:17
  9. Interest in the use of engineered microbes to deliver therapeutic activities has increased in recent years. The probiotic yeast Saccharomyces boulardii has been investigated for production of therapeutics in the ...

    Authors: Carmen Sands, Karl Alex Hedin, Ruben Vazquez-Uribe and Morten Otto Alexander Sommer
    Citation: Microbial Cell Factories 2024 23:16
  10. Attenuation of camptothecin (CPT) productivity by fungi with preservation and subculturing is the challenge that halts fungi to be an industrial platform of CPT production. Thus, screening for novel endophytic...

    Authors: Ashraf S. A. El-Sayed, Abdelaleim I. ElSayed, Khalid M. Wadan, Sayed S. El-Saadany and Nouran A. A. Abd El-Hady
    Citation: Microbial Cell Factories 2024 23:15
  11. Escherichia coli is a cost-effective expression system for production of antibody fragments like Fabs. Various yield improvement strategies have been applied, however, Fabs remain challenging to produce. This stu...

    Authors: Sophie Vazulka, Matteo Schiavinato, Christopher Tauer, Martin Wagenknecht, Monika Cserjan-Puschmann and Gerald Striedner
    Citation: Microbial Cell Factories 2024 23:14
  12. S. lividans TK24 is a popular host for the production of small molecules and the secretion of heterologous protein. Within its large genome, twenty-nine non-essential clusters direct the biosynthesis of secondary...

    Authors: Mohamed Belal Hamed, Tobias Busche, Kenneth Simoens, Sebastien Carpentier, Jan Kormanec, Lieve Van Mellaert, Jozef Anné, Joern Kalinowski, Kristel Bernaerts, Spyridoula Karamanou and Anastassios Economou
    Citation: Microbial Cell Factories 2024 23:13
  13. L-phenylalanine is an essential amino acid with various promising applications. The microbial pathway for L-phenylalanine synthesis from glucose in wild strains involves lengthy steps and stringent feedback re...

    Authors: Mengzhen Nie, Jingyu Wang, Zeyao Chen, Chenkai Cao and Kechun Zhang
    Citation: Microbial Cell Factories 2024 23:12

    The Correction to this article has been published in Microbial Cell Factories 2024 23:46

  14. The demand for low-cost cellulolytic enzyme synthesis is rising in the enzyme market. This work aims to produce cellulase by utilizing various agricultural wastes and investigating the use of enzyme in sacchar...

    Authors: Faten A. Mostafa, Hala R. Wehaidy, Samar Sharaf, Heba M. El-Hennawi, Safia A. Mahmoud and Shireen A.A. Saleh
    Citation: Microbial Cell Factories 2024 23:11
  15. Existing plasmid systems offer a fundamental foundation for gene expression in Cupriavidus necator; however, their applicability is constrained by the limitations of conjugation. Low segregational stabilities and...

    Authors: Simon Arhar, Thomas Rauter, Holly Stolterfoht-Stock, Vera Lambauer, Regina Kratzer, Margit Winkler, Marianna Karava, Robert Kourist and Anita Emmerstorfer-Augustin
    Citation: Microbial Cell Factories 2024 23:9
  16. One carbon (C1) molecules such as methanol have the potential to become sustainable feedstocks for biotechnological processes, as they can be derived from CO2 and green hydrogen, without the need for arable land....

    Authors: Katrin Wefelmeier, Simone Schmitz, Benjamin Jonas Kösters, Ulf Winfried Liebal and Lars Mathias Blank
    Citation: Microbial Cell Factories 2024 23:8
  17. The 5´ untranslated region (5´ UTR) plays a key role in regulating translation efficiency and mRNA stability, making it a favored target in genetic engineering and synthetic biology. A common feature found in ...

    Authors: Junyuan Zeng, Kunfeng Song, Jingqi Wang, Haimei Wen, Jungang Zhou, Ting Ni, Hong Lu and Yao Yu
    Citation: Microbial Cell Factories 2024 23:7
  18. Clostridium sp. AWRP (AWRP) is a novel acetogenic bacterium isolated under high partial pressure of carbon monoxide (CO) and can be one of promising candidates for alcohol production from carbon oxides. Compared ...

    Authors: Hae Jun Kwon, Joungmin Lee, Soo Jae Kwon and Hyun Sook Lee
    Citation: Microbial Cell Factories 2024 23:6
  19. Reprogramming microorganisms to enhance the production of metabolites is a part of contemporary synthetic biology, which relies on the availability of genetic tools to successfully manipulate the bacteria. Methyl...

    Authors: Liping Zhu, Yazhen Song, Shunan Ma and Song Yang
    Citation: Microbial Cell Factories 2024 23:5
  20. The supply of ATP is a limiting factor for cellular metabolism. Therefore, cell factories require a sufficient ATP supply to drive metabolism for efficient bioproduction. In the current study, a light-driven p...

    Authors: Kaoru M. Daicho, Yoko Hirono-Hara, Hiroshi Kikukawa, Kentaro Tamura and Kiyotaka Y. Hara
    Citation: Microbial Cell Factories 2024 23:4
  21. Antibiotics biosynthesis is usually regulated by the cluster-situated regulatory gene(s) (CSRG(s)), which directly regulate the genes within the corresponding biosynthetic gene cluster (BGC). Previously, we ha...

    Authors: Yue Mao, Xianyan Zhang, Tianyu Zhou, Bingbing Hou, Jiang Ye, Haizhen Wu, Ruida Wang and Huizhan Zhang
    Citation: Microbial Cell Factories 2024 23:3
  22. Haloarchaea produce bacterioruberin, a major C50 carotenoid with antioxidant properties that allow for its potential application in the food, cosmetic, and pharmaceutical industries. This study aimed to optimize ...

    Authors: Chi Young Hwang, Eui-Sang Cho, Sungjun Kim, Kyobum Kim and Myung-Ji Seo
    Citation: Microbial Cell Factories 2024 23:2
  23. Transforming waste and nonfood materials into bulk biofuels and chemicals represents a major stride in creating a sustainable bioindustry to optimize the use of resources while reducing environmental footprint...

    Authors: Kyoyoung Seo, Wei Shu, Christian Rückert-Reed, Patrick Gerlinger, Tobias J. Erb, Jörn Kalinowski and Christoph Wittmann
    Citation: Microbial Cell Factories 2023 22:262
  24. Monitoring and control of both growth media and microbial biomass is extremely important for the development of economical bioprocesses. Unfortunately, process monitoring is still dependent on a limited number...

    Authors: Simona Dzurendova, Pernille Margrethe Olsen, Dana Byrtusová, Valeria Tafintseva, Volha Shapaval, Svein Jarle Horn, Achim Kohler, Martin Szotkowski, Ivana Marova and Boris Zimmermann
    Citation: Microbial Cell Factories 2023 22:261
  25. RNA-dependent RNA polymerase (RdRp) is a good target of anti-RNA virus agents; not only it is pivotal for the RNA virus replication cycle and highly conserved among RNA viruses across different families, but a...

    Authors: Kantaphon Glab-ampai, Kodchakorn Mahasongkram, Monrat Chulanetra, Thanatsaran Saenlom, Kanyarat Thueng-in, Nitat Sookrung and Wanpen Chaicumpa
    Citation: Microbial Cell Factories 2023 22:260
  26. Komagataella phaffii (Pichia pastoris) is a methylotrophic commercially important non-conventional species of yeast that grows in a fermentor to exceptionally high densities on simple media and secretes recombina...

    Authors: Dariusz Abramczyk, Maria del Carmen Sanchez Olmos, Adan Andres Ramirez Rojas, Daniel Schindler, Daniel Robertson, Stephen McColm, Adele L. Marston and Paul N. Barlow
    Citation: Microbial Cell Factories 2023 22:259
  27. Color chemicals contaminate pure water constantly discharged from different points and non-point sources. Physical and chemical techniques have certain limitations and complexities for bioenergy production, wh...

    Authors: Aisha Umar, Islem Abid, Mohammed Antar, Laurent Dufossé, Lobna Hajji-Hedfi, Mohamed S. Elshikh, Abeer El Shahawy and Ahmed M. Abdel-Azeem
    Citation: Microbial Cell Factories 2023 22:258
  28. Streptomyces lincolnensis is well known for producing the clinically important antimicrobial agent lincomycin. The synthetic and regulatory mechanisms on lincomycin biosynthesis have been deeply explored in recen...

    Authors: Chun-Yan Lin, Yixian Ru, Yanchao Jin, Qi Lin and Guang-Rong Zhao
    Citation: Microbial Cell Factories 2023 22:257
  29. Gamma-aminobutyric acid (GABA) is a non-protein amino acid with neuroinhibitory, antidiabetic, and antihypertensive properties and is used as a drug for treating anxiety and depression. Some strains of lactoba...

    Authors: Sumanpreet Kaur, Preeti Sharma, Melinda J. Mayer, Saskia Neuert, Arjan Narbad and Sukhraj Kaur
    Citation: Microbial Cell Factories 2023 22:256
  30. Uridyl peptide compounds are renowned as a subclass of nucleoside antibiotics for their highly specific antibacterial activity against Gram-negative bacteria and the unique target of action. We previously acti...

    Authors: Ning Liu, Yang Xu, Fei Shang, Huiying Sun, Xiang Liu, Ying Huang, Huarong Tan and Jihui Zhang
    Citation: Microbial Cell Factories 2023 22:255
  31. It is increasingly recognized that conventional food production systems are not able to meet the globally increasing protein needs, resulting in overexploitation and depletion of resources, and environmental d...

    Authors: Myrsini Sakarika, Frederiek-Maarten Kerckhof, Lotte Van Peteghem, Alexandra Pereira, Tim Van Den Bossche, Robbin Bouwmeester, Ralf Gabriels, Delphi Van Haver, Barbara Ulčar, Lennart Martens, Francis Impens, Nico Boon, Ramon Ganigué and Korneel Rabaey
    Citation: Microbial Cell Factories 2023 22:254
  32. Cordycepin (3′-deoxyadenosine) is an important bioactive compound in medical and healthcare markets. The drawbacks of commercial cordycepin production using Cordyceps spp. include long cultivation periods and low...

    Authors: Sukanya Jeennor, Jutamas Anantayanon, Sarocha Panchanawaporn, Chanikul Chutrakul, Wanwipa Vongsangnak and Kobkul Laoteng
    Citation: Microbial Cell Factories 2023 22:253
  33. Pectinase is a particular type of enzyme that can break down pectin compounds and is extensively utilised in the agricultural field. In this study, twenty yeast isolates were isolated and assayed for pectinase...

    Authors: Nagwa M. Abd El-Aziz, Maysa E. Moharam, Nora N. El-Gamal and Bigad E. Khalil
    Citation: Microbial Cell Factories 2023 22:252
  34. In yeast, recombinant membrane proteins including viral scaffold proteins used for the formation of enveloped Virus-like particles (eVLPs) typically accumulate intracellularly. Their recovery is carried out by...

    Authors: Valentina Ganeva and Andreas Kranz
    Citation: Microbial Cell Factories 2023 22:251
  35. Identifying individual characteristics based on trace evidence left at a crime scene is crucial in forensic identification. Microbial communities found in fecal traces have high individual specificity and coul...

    Authors: Yu Liang, Shujie Dou, Guangzhong Zhao, Jie Shen, Guangping Fu, Lihong Fu, Shujin Li, Bin Cong and Chunnan Dong
    Citation: Microbial Cell Factories 2023 22:250
  36. Authors: Ernesta Augustiniene, Ilona Jonuskiene, Jurgita Kailiuviene, Edita Mazoniene, Kestutis Baltakys and Naglis Malys
    Citation: Microbial Cell Factories 2023 22:249

    The original article was published in Microbial Cell Factories 2023 22:223

  37. Intracellular hyperaccumulation of phycocyanin (PC) and its high susceptibility to degradation at higher temperatures are major challenging problems associated with its production from cyanobacteria. The prese...

    Authors: Mohamed Gomaa, Shimaa Abdelmohsen Ali and Awatief F. Hifney
    Citation: Microbial Cell Factories 2023 22:248
  38. Photosynthetic cyanobacterial components are gaining great economic importance as prospective low-cost biostimulants for the green synthesis of metal nanoparticles with valuable medical and industrial applicat...

    Authors: Asmaa H. Al-Badwy, Ahmed M. Khalil, Ali H. Bashal and Rashad Kebeish
    Citation: Microbial Cell Factories 2023 22:247
  39. Biodiesel, unlike to its fossil-based homologue (diesel), is renewable. Its use contributes to greater sustainability in the energy sector, mainly by reducing greenhouse gas emissions. Current biodiesel produc...

    Authors: María Gallego-García, Ana Susmozas, María José Negro and Antonio D. Moreno
    Citation: Microbial Cell Factories 2023 22:246
  40. Removal of trace organic chemicals (TOrCs) in aquatic environments has been intensively studied. Some members of natural microbial communities play a vital role in transforming chemical contaminants, however, ...

    Authors: Lijia Cao, Sarahi L. Garcia and Christian Wurzbacher
    Citation: Microbial Cell Factories 2023 22:245
  41. Protein complex assembly facilitates the combination of individual protein subunits into functional entities, and thus plays a crucial role in biology and biotechnology. Recently, we developed quasi-twodimensi...

    Authors: Stefanie Förste, Ohad Vonshak, Shirley S. Daube, Roy H. Bar-Ziv, Reinhard Lipowsky and Sophia Rudorf
    Citation: Microbial Cell Factories 2023 22:244
  42. Integrated metabolic engineering approaches that combine system and synthetic biology tools enable the efficient design of microbial cell factories for synthesizing high-value products. In this study, we utili...

    Authors: Koray Malcı, Rodrigo Santibáñez, Nestor Jonguitud-Borrego, Jorge H. Santoyo-Garcia, Eduard J. Kerkhoven and Leonardo Rios-Solis
    Citation: Microbial Cell Factories 2023 22:243
  43. Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process....

    Authors: Mathias Gotsmy, Florian Strobl, Florian Weiß, Petra Gruber, Barbara Kraus, Juergen Mairhofer and Jürgen Zanghellini
    Citation: Microbial Cell Factories 2023 22:242
  44. In whole-cell bio-catalysis, the biosystems engineering paradigm shifts from the global reconfiguration of cellular metabolism as in fermentation to a more focused, and more easily modularized, optimization of...

    Authors: Sabine Schelch, Manuel Eibinger, Jasmin Zuson, Jürgen Kuballa and Bernd Nidetzky
    Citation: Microbial Cell Factories 2023 22:241
  45. trans-4-Hydroxyproline (T-4-HYP) is a promising intermediate in the synthesis of antibiotic drugs. However, its industrial production remains challenging due to the low production efficiency of T-4-HYP. This stud...

    Authors: Yu Gong, Ruiqi Wang, Ling Ma, Shuo Wang, Changgeng Li and Qingyang Xu
    Citation: Microbial Cell Factories 2023 22:240
  46. (Hydroxy)cinnamyl alcohols and allylphenols, including coniferyl alcohol and eugenol, are naturally occurring aromatic compounds widely utilised in pharmaceuticals, flavours, and fragrances. Traditionally, the...

    Authors: Erik K. R. Hanko, Kris Niño G. Valdehuesa, Koen J. A. Verhagen, Jakub Chromy, Ruth A. Stoney, Jeremy Chua, Cunyu Yan, Johannes A. Roubos, Joep Schmitz and Rainer Breitling
    Citation: Microbial Cell Factories 2023 22:238
  47. Methanol is increasingly gaining attraction as renewable carbon source to produce specialty and commodity chemicals, as it can be generated from renewable sources such as carbon dioxide (CO2). In this context, na...

    Authors: Sílvia Àvila-Cabré, Míriam Pérez-Trujillo, Joan Albiol and Pau Ferrer
    Citation: Microbial Cell Factories 2023 22:237

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