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  1. Malachite Green (MG) dye of the triphenylmethane group is a toxic compound used in the aquaculture industry as an antifungal agent, however, it can accumulate in fish and pose toxicity. The present work aims t...

    Authors: Abanaoub Efraim, Mai Saeed, Mariam Ahmed Elbaz, Mohamed Alaa, Noran Ahmed, Rana Adel, Yara Hazem, Einas Elshatoury and Ola M. Gomaa
    Citation: Microbial Cell Factories 2023 22:142
  2. The purpose of the current study is to isolate a heavily amylase-producing bacteria of the genus Bacillus from soil samples, optimize the production of the enzyme, purify it, and evaluate its activity against bio...

    Authors: Amal M. Abo-Kamer, Ibrahim S. Abd-El-salam, Faten A. Mostafa, Abd-El-Rahman A. Mustafa and Lamiaa A. Al-Madboly
    Citation: Microbial Cell Factories 2023 22:141
  3. A sustainable biorefining and bioprocessing strategy was developed to produce edible-ulvan films and non-edible polyhydroxybutyrate films. The preparation of edible-ulvan films by crosslinking and plasticisati...

    Authors: N. Arul Manikandan and Piet N. L. Lens
    Citation: Microbial Cell Factories 2023 22:140
  4. Triterpenoids have shown a wide range of biological activities including antitumor and antiviral effects. Typically, triterpenes are synthesized through the mevalonate pathway and are extracted from natural pl...

    Authors: Xinwei Wang, Haibo Wu, Ka Hong Wong, Yixuan Wang, Baixiong Chen and Kun Feng
    Citation: Microbial Cell Factories 2023 22:139
  5. As a concentrated energy source with high added value, hydrogen has great development prospects, with special emphasis on sustainable microbial production as a replacement for traditional fossil fuels. In this...

    Authors: Ke Jiang, Ruoxuan Bai, Ting Gao, Ping Lu, Jingya Zhang, Shuting Zhang, Fangxu Xu, Shenghou Wang and Hongxin Zhao
    Citation: Microbial Cell Factories 2023 22:137
  6. Beet filter cake (BFC) is a by-product of sugar beet processing, which is difficult to dispose of and involves severe environmental concerns. Spirulina platensis is a microalga with a high protein content essenti...

    Authors: Sara Saad, Mervat Hosny Hussien, Ghada Samir Abou-ElWafa, Heshmat Soliman Aldesuquy and Eladl Eltanahy
    Citation: Microbial Cell Factories 2023 22:136
  7. Ablynx NV, a subsidiary of Sanofi, has a long-standing focus on the development of Nanobody® molecules as biopharmaceuticals (Nanobody® is a registered trademark of Ablynx NV). Nanobody molecules are single va...

    Authors: Manu De Groeve, Bram Laukens and Peter Schotte
    Citation: Microbial Cell Factories 2023 22:135
  8. Hydrogenases (H2ases) are metalloenzymes capable of the reversible conversion of protons and electrons to molecular hydrogen. Exploiting the unique enzymatic activity of H2ases can lead to advancements in the ...

    Authors: Malgorzata Witkowska, Robert P. Jedrzejczak, Andrzej Joachimiak, Onur Cavdar, Anna Malankowska, Piotr M. Skowron and Agnieszka Zylicz-Stachula
    Citation: Microbial Cell Factories 2023 22:134
  9. The global market of plant-based milk alternatives is continually growing. Flavour and taste have a key impact on consumers’ selection of plant-based beverages. Unfortunately, natural plant milks have only lim...

    Authors: Muzi Tangyu, Michel Fritz, Jan Patrick Tan, Lijuan Ye, Christoph J. Bolten, Biljana Bogicevic and Christoph Wittmann
    Citation: Microbial Cell Factories 2023 22:133
  10. Actinomycetes Streptomyces davaonensis and Streptomyces cinnabarinus synthesize a promising broad-spectrum antibiotic roseoflavin, with its synthesis starting from flavin mononucleotide and proceeding through an ...

    Authors: Kostyantyn V. Dmytruk, Justyna Ruchala, Liubov R. Fayura, Grzegorz Chrzanowski, Olena V. Dmytruk, Andriy O. Tsyrulnyk, Yuliia A. Andreieva, Daria V. Fedorovych, Olena I. Motyka, Diethard Mattanovich, Hans Marx and Andriy A. Sibirny
    Citation: Microbial Cell Factories 2023 22:132
  11. Escherichia coli is a useful platform for producing valuable materials through the implementation of synthetic gene(s) derived from other organisms. The production of lactate (LA)-based polyester poly[LA-co-3-hyd...

    Authors: Yuki Nagao, Sangho Koh, Seiichi Taguchi and Tomohiro Shimada
    Citation: Microbial Cell Factories 2023 22:131
  12. Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, includ...

    Authors: Laura M. Helleckes, Debora Puchta, Hannah Czech, Holger Morschett, Bertram Geinitz, Wolfgang Wiechert and Marco Oldiges
    Citation: Microbial Cell Factories 2023 22:130
  13. Polyhydroxybutyrate (PHB) is currently the most common polymer produced by natural bacteria and alternative to conventional petrochemical-based plastics due to its similar material properties and biodegradabil...

    Authors: Nan Jiang, Ming Wang, Linxin Song, Dengbin Yu, Shuangzi Zhou, Yu Li, Haiyan Li and Xuerong Han
    Citation: Microbial Cell Factories 2023 22:129
  14. Mitochondrial carriers (MCs) can deeply affect the intracellular flux distribution of metabolic pathways. The manipulation of their expression level, to redirect the flux toward the production of a molecule of...

    Authors: Eugenia Messina, Camilla Pires de Souza, Claudia Cappella, Simona Nicole Barile, Pasquale Scarcia, Isabella Pisano, Luigi Palmieri, Jean-Marc Nicaud and Gennaro Agrimi
    Citation: Microbial Cell Factories 2023 22:128
  15. Streptomyces are well known for their potential to produce various pharmaceutically active compounds, the commercial development of which is often limited by the low productivity and purity of the desired compoun...

    Authors: Wenli Guo, Zhihong Xiao, Tingting Huang, Kai Zhang, Hai-Xue Pan, Gong-Li Tang, Zixin Deng, Rubing Liang and Shuangjun Lin
    Citation: Microbial Cell Factories 2023 22:127
  16. Biosurfactants are surface-active compounds with environmental and industrial applications. These molecules show higher biocompatibility, stability and efficiency compared to synthetic surfactants. On the othe...

    Authors: Marco Andreolli, Valeria Villanova, Serena Zanzoni, Mariapina D’Onofrio, Giovanni Vallini, Nicola Secchi and Silvia Lampis
    Citation: Microbial Cell Factories 2023 22:126
  17. Mammalian metallothioneins (MTs) are small (6–7 kDa), intracellular, cysteine-rich, metal-binding proteins involved, inter alia, in the homeostasis of zinc and copper, detoxification of heavy metals, antioxida...

    Authors: Avinash Kumar Singh and Artur Krężel
    Citation: Microbial Cell Factories 2023 22:125
  18. As simplistic proteinaceous carriers of genetic material, phages offer great potential as targeted vectors for mammalian transgene delivery. The filamentous phage M13 is a single-stranded DNA phage with attrac...

    Authors: Shirley Wong, Salma Jimenez and Roderick A. Slavcev
    Citation: Microbial Cell Factories 2023 22:124
  19. Glucose repression in yeast leads to the sequential or diauxic utilization of mixed sugars and reduces the co-utilization of glucose and xylose from lignocellulosic biomasses. Study of the glucose sensing path...

    Authors: Lingya Wang, Anran Wang, Dongmei Wang and Jiong Hong
    Citation: Microbial Cell Factories 2023 22:123
  20. Chemical fertilizers have greatly contributed to the development of agriculture, but alternative fertilizers are needed for the sustainable development of agriculture. 2,3-butanediol (2,3-BDO) is a promising b...

    Authors: Jung-Hyun Ju, Min-Ho Jo, Sun-Yeon Heo, Min-Soo Kim, Chul-Ho Kim, Narayan Chandra Paul, Hyunkyu Sang and Baek-Rock Oh
    Citation: Microbial Cell Factories 2023 22:121
  21. Biobased 5-(hydroxymethyl)furfural (5-HMF) is an important platform that offers numerous possibilities for upgrading to a range of chemical, material and fuel products. One reaction of special interest is the ...

    Authors: Sara Jonsdottir Glaser, Sang-Hyun Pyo, Nicola Rehnberg, Dörte Rother and Rajni Hatti-Kaul
    Citation: Microbial Cell Factories 2023 22:120
  22. A processing methodology of raw starch extraction from avocado seeds (ASs) and a sequential hydrolysis and fermentation bioprocess in just a few steps was successfully obtained for the bioethanol production by...

    Authors: Luis Caballero-Sanchez, Pedro E. Lázaro-Mixteco, Alejandra Vargas-Tah and Agustín J. Castro-Montoya
    Citation: Microbial Cell Factories 2023 22:119
  23. Raw starch-degrading α-amylase (RSDA) can hydrolyze raw starch at moderate temperatures, thus contributing to savings in starch processing costs. However, the low production level of RSDA limits its industrial...

    Authors: Dongbang Yao, Xudong Han, Huanhuan Gao, Bin Wang, Zemin Fang, He Li, Wei Fang and Yazhong Xiao
    Citation: Microbial Cell Factories 2023 22:118
  24. Production of 3-hydroxypropionic acid (3-HP) through the malonyl-CoA pathway has yielded promising results in Pichia pastoris (Komagataella phaffii), demonstrating the potential of this cell factory to produce th...

    Authors: Albert Fina, Pierre Millard, Joan Albiol, Pau Ferrer and Stephanie Heux
    Citation: Microbial Cell Factories 2023 22:117
  25. 17β-estradiol (E2) residues exhibit harmful effects both for human and animals and have got global attention of the scientific community. Microbial enzymes are considered as one of the effective strategies hav...

    Authors: Peng Hao, Hanyu Pan, Zongshuo Lv, Jingyi Zhang, Lixia Wang, Yanbin Zhu, Wangdui Basang and Yunhang Gao
    Citation: Microbial Cell Factories 2023 22:116
  26. Chinese Nong-favor daqu, the presentative liquor starter of Baijiu, has been enriched with huge amounts of enzymes in degrading various biological macromolecules by openly man-made process for thousand years. ...

    Authors: Zhuolin Yi, Lanchai Chen, Yanling Jin, Yi Shen, Nian Liu, Yang Fang, Yao Xiao, Xi Wang, Kui Peng, Kaize He and Hai Zhao
    Citation: Microbial Cell Factories 2023 22:114
  27. Compared with steviol glycosides, the taste of glucosylated steviol glycosides is better and more similar to that of sucrose. At present, cyclodextrin glucanotransferase (CGTase) is primarily used to catalyze ...

    Authors: Ruiqin Zhang, Ruiqi Tang, Wei Wang, Jiahua Bi, Xianrui Xu, Qiuling Fan, Yanjun Li and Qihe Chen
    Citation: Microbial Cell Factories 2023 22:113
  28. Bifidobacteria are representative intestinal probiotics that have extremely high application value in the food and medical fields. However, the lack of molecular biology tools limits the research on functional ge...

    Authors: Jiao Li, Xin Song, Zhiqiang Xiong, Guangqiang Wang, Yongjun Xia, Yijin Yang and Lianzhong Ai
    Citation: Microbial Cell Factories 2023 22:112
  29. Lactic Acid Bacteria such as Lactococcus lactis, Latilactobacillus sakei (basonym: Lactobacillus sakei) and Lactiplantibacillus plantarum (basonym: Lactobacillus plantarum) have gained importance as recombinant c...

    Authors: Ricardo Baltà-Foix, Caterina Serrano-Adrover, Adrià López-Cano, Laia Gifre-Renom, Alejandro Sanchez-Chardi, Anna Arís and Elena Garcia-Fruitós
    Citation: Microbial Cell Factories 2023 22:111
  30. A subject of great interest is the bioprospecting of microorganisms and their bioactive byproducts, such as pigments. Microbial pigments have various benefits, including being safe to use due to their natural ...

    Authors: Ahmed A. Abdelaziz, Amal M. Abo Kamer, Khaled B. Al-Monofy and Lamiaa A. Al-Madboly
    Citation: Microbial Cell Factories 2023 22:110
  31. The probiotic yeast Saccharomyces boulardii (Sb) is a promising chassis to deliver therapeutic proteins to the gut due to Sb’s innate therapeutic properties, resistance to phage and antibiotics, and high protein ...

    Authors: Deniz Durmusoglu, Ibrahim Al’Abri, Zidan Li, Taufika Islam Williams, Leonard B. Collins, José L. Martínez and Nathan Crook
    Citation: Microbial Cell Factories 2023 22:109
  32. With the dramatic decrease in fossil fuel stocks and their detrimental effects on the environment, renewable energy sources have gained imminent importance in the mitigation of emissions. As lipid-enriched ene...

    Authors: Yavuz S. Yalcin, Busra Aydin, Huan Chen, Samson Gichuki and Viji Sitther
    Citation: Microbial Cell Factories 2023 22:108
  33. Human life has been significantly impacted by the creation and spread of novel species of antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and researchers have recently ...

    Authors: Amr H. Hashem, Mohamed S. Attia, Eslam K. Kandil, Mahmoud M. Fawzi, Ahmed S. Abdelrahman, Mohamed S. Khader, Mohamed A. Khodaira, Abdallah E. Emam, Mohamed A. Goma and Amer M. Abdelaziz
    Citation: Microbial Cell Factories 2023 22:107

    The Correction to this article has been published in Microbial Cell Factories 2023 22:122

  34. Biofloc technology aims to maximize fish farming productivity by effectively breaking down ammonia and nitrite, promoting healthy flocculation, and enhancing the growth and immunity of cultured animals. Howeve...

    Authors: Vikash Kumar, Himanshu Sekhar Swain, Paton Vuong, Suvra Roy, Aurobinda Upadhyay, Ramesh Chandra Malick, Kampan Bisai, Parwinder Kaur and Basanta Kumar Das
    Citation: Microbial Cell Factories 2023 22:106
  35. Previously, we isolated a riboflavin-overproducing Ashbya gossypii mutant (MT strain) and discovered some mutations in genes encoding flavoproteins. Here, we analyzed the riboflavin production in the MT strain, i...

    Authors: Tatsuya Kato, Mai Kano, Ami Yokomori, Junya Azegami, Hesham A. El Enshasy and Enoch Y. Park
    Citation: Microbial Cell Factories 2023 22:105
  36. In the biopharmaceutical industry, Escherichia coli is one of the preferred expression hosts for large-scale production of therapeutic proteins. Although increasing the product yield is important, product quality...

    Authors: Klaudia Arauzo-Aguilera, Luisa Buscajoni, Karin Koch, Gary Thompson, Colin Robinson and Matthias Berkemeyer
    Citation: Microbial Cell Factories 2023 22:104
  37. The filamentous fungus Trichoderma reesei has been used as a host organism for the production of lignocellulosic biomass-degrading enzymes. Although this microorganism has high potential for protein production, i...

    Authors: Toshiharu Arai, Mayumi Wada, Hiroki Nishiguchi, Yasushi Takimura and Jun Ishii
    Citation: Microbial Cell Factories 2023 22:103
  38. Heme is an iron/porphyrin complex compound, widely used in the health care, food, and pharmaceutical industries. It is more advantageous and attractive to develop microbial cell factories to produce heme by fe...

    Authors: Shaomei Yang, Anlong Wang, Jiachang Li, Yunhang Shao, Fengjie Sun, Shucheng Li, Kai Cao, Hongliang Liu, Peng Xiong and Zhengquan Gao
    Citation: Microbial Cell Factories 2023 22:102
  39. The nanoparticles (NPs) formed by Enterococcus thailandicus, Pseudomonas putida, Marinobacter hydrocarbonoclasticus, and P. geniculate were tested against soft rot/blackleg genera. The effects of NPs recorded on ...

    Authors: Alia A. Shoeib, Nader A. Ashmawy, Ayman Kamal and Sahar Abd El Fatah Zaki
    Citation: Microbial Cell Factories 2023 22:101
  40. Human epidermal growth factor receptor 2 (HER2) positive breast cancer is an aggressive subtype, accounting for around 20% of all breast cancers. The development of HER2-targeted therapy has substantially impr...

    Authors: Yanjie Peng, Zhengli Wu, Zheng Pang, Lin Zhang, Dandan Song, Fang Liu, Yanhong Li and Tongjun Lin
    Citation: Microbial Cell Factories 2023 22:100
  41. In research and production, reproducibility is a key factor, to meet high quality and safety standards and maintain productivity. For microbial fermentations, complex substrates and media components are often ...

    Authors: Sarah Sparviero, Max Daniel Dicke, Tobias M. Rosch, Tania Castillo, Holjes Salgado-Lugo, Enrique Galindo, Carlos Peña and Jochen Büchs
    Citation: Microbial Cell Factories 2023 22:99
  42. Palifermin (trade name Kepivance®) is an amino-terminally truncated recombinant human keratinocyte growth factor 1 (KGF-1) with 140 residues that has been produced using Escherichia coli to prevent and treat oral...

    Authors: Young Su Kim, Hye-Jeong Lee, Gabriella Aphrodita Handoko, Jaehui Kim, Seong-Bo Kim, Minho Won, Jung-Ho Park and Jungoh Ahn
    Citation: Microbial Cell Factories 2023 22:98
  43. The filamentous fungus Trichoderma reesei (teleomorph Hypocrea jecorina, Ascomycota) is a well-known lignocellulolytic enzymes-producing strain in industry. To increase the fermentation titer of lignocellulolytic...

    Authors: Chixiang Ma, Jialong Liu, Jiaxin Tang, Yuanlu Sun, Xiaojie Jiang, Tongtong Zhang, Yan Feng, Qinghua Liu and Lei Wang
    Citation: Microbial Cell Factories 2023 22:97
  44. The use of probiotic lactic acid bacteria as a mucosal vaccine vector is considered a promising alternative compared to the use of other microorganisms because of its “Generally Regarded as Safe” status, its p...

    Authors: In-Chan Hwang, Valerie Diane Valeriano, Ji Hoon Song, Marcela Pereira, Ju Kyoung Oh, Kyudong Han, Lars Engstrand and Dae-Kyung Kang
    Citation: Microbial Cell Factories 2023 22:96
  45. Engineered strains of Escherichia coli have been used to produce bioconjugate vaccines using Protein Glycan Coupling Technology (PGCT). Nanovaccines have also entered the vaccine development arena with advances i...

    Authors: Yan Liu, Chao Pan, Kangfeng Wang, Yan Guo, YanGe Sun, Xiang Li, Peng Sun, Jun Wu, Hengliang Wang and Li Zhu
    Citation: Microbial Cell Factories 2023 22:95
  46. Due to the therapeutic importance of microbial pigments, these pigments are receiving the attention of researchers. In this present study 60 isolates were isolated from sediments of Abu-Qir coast of the Medite...

    Authors: Walaa M. Ibrahim, Zakia A. Olama, G. M. Abou-elela, Heba S. Ramadan, Ghada E. Hegazy and Dalia El S. El Badan
    Citation: Microbial Cell Factories 2023 22:94
  47. Prolyl endopeptidase from Aspergillus niger (AN-PEP) is a prominent serine proteinase with various potential applications in the food and pharmaceutical industries. However, the availability of efficient and low-...

    Authors: Minglu Liu, Meng Hu, Hui Zhou, Zhiyang Dong and Xiuzhen Chen
    Citation: Microbial Cell Factories 2023 22:93

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