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  1. Pregnenolone and progesterone are the life-important steroid hormones regulating essential vital functions in mammals, and widely used in different fields of medicine. Microbiological production of these compo...

    Authors: Mikhail Karpov, Nicolai Strizhov, Ludmila Novikova, Tatyana Lobastova, Sergey Khomutov, Andrei Shutov, Alexey Kazantsev and Marina Donova
    Citation: Microbial Cell Factories 2024 23:105
  2. The macrolide antibiotic avermectin, a natural product derived from Streptomyces avermitilis, finds extensive applications in agriculture, animal husbandry and medicine. The mtrA (sav_5063) gene functions as a tr...

    Authors: Jinpin Tian, Yue Li, Chuanbo Zhang, Jianyu Su and Wenyu Lu
    Citation: Microbial Cell Factories 2024 23:103
  3. Poultry feather waste has a potential for bioenergy production because of its high protein content. This research explored the use of chicken feather hydrolysate for methane and hydrogen production via anaerob...

    Authors: Dina Hassan El Salamony, Mohamed Salah Eldin Hassouna, Taha Ibrahim Zaghloul, Zhen He and Hanan Moustafa Abdallah
    Citation: Microbial Cell Factories 2024 23:102
  4. Short-chain fatty acids (SCFAs) are cost-effective carbon sources for an affordable production of lipids. Hexanoic acid, the acid with the longest carbon chain in the SCFAs pool, is produced in anaerobic ferme...

    Authors: Sergio Morales-Palomo, Clara Navarrete, José Luis Martínez, Cristina González-Fernández and Elia Tomás-Pejó
    Citation: Microbial Cell Factories 2024 23:101
  5. Surfactin is a cyclic hexalipopeptide compound, nonribosomal synthesized by representatives of the Bacillus subtilis species complex which includes B. subtilis group and its closely related species, such as B. su...

    Authors: Junqing Qiao, Rainer Borriss, Kai Sun, Rongsheng Zhang, Xijun Chen, Youzhou Liu and Yongfeng Liu
    Citation: Microbial Cell Factories 2024 23:100
  6. The yeast Komagataella phaffii has become a very popular host for heterologous protein expression, very often based on the use of the AOX1 promoter, which becomes activated when cells are grown with methanol as a...

    Authors: Marcel Albacar, Antonio Casamayor and Joaquín Ariño
    Citation: Microbial Cell Factories 2024 23:99
  7. Bacteria of the genus Photorhabdus and Xenorhabdus are motile, Gram-negative bacteria that live in symbiosis with entomopathogenic nematodes. Due to their complex life cycle, they produce a large number of specia...

    Authors: Alexander Rill, Lei Zhao and Helge B. Bode
    Citation: Microbial Cell Factories 2024 23:98
  8. Biotransformation of waste oil into value-added nutraceuticals provides a sustainable strategy. Thraustochytrids are heterotrophic marine protists and promising producers of omega (ω) fatty acids. Although the...

    Authors: Iqra Mariam, Eleni Krikigianni, Chloe Rantzos, Maurizio Bettiga, Paul Christakopoulos, Ulrika Rova, Leonidas Matsakas and Alok Patel
    Citation: Microbial Cell Factories 2024 23:97
  9. Engineering bacterial strains to redirect the metabolism towards the production of a specific product has enabled the development of industrial biotechnology. However, rewiring the metabolism can have severe i...

    Authors: Sofie Snoeck, Chiara Guidi and Marjan De Mey
    Citation: Microbial Cell Factories 2024 23:96
  10. Surfactin, a green lipopeptide bio-surfactant, exhibits excellent surface, hemolytic, antibacterial, and emulsifying activities. However, a lack of clear understanding of the synthesis regulation mechanism of ...

    Authors: Yumeng Su, Ling Gao, Chenyu Li, Liang Wang, Huimin Zhou, Chenhao Zhang and Xiaole Xia
    Citation: Microbial Cell Factories 2024 23:94
  11. Fungal non-ribosomal peptide synthetase (NRPS)-encoding products play a paramount role in new drug discovery. Fusarium, one of the most common filamentous fungi, is well-known for its biosynthetic potential of NR...

    Authors: Ziwei Huang, Wangjie Zhu, Yifan Bai, Xuelian Bai and Huawei Zhang
    Citation: Microbial Cell Factories 2024 23:93
  12. Propionic acid fermentation from renewable feedstock suffers from low volumetric productivity and final product concentration, which limits the industrial feasibility of the microbial route. High cell density ...

    Authors: Tarek Dishisha, Mridul Jain and Rajni Hatti-Kaul
    Citation: Microbial Cell Factories 2024 23:91
  13. Cellular lipid membranes serve as the primary barrier preventing viral infection of the host cell and provide viruses with a critical initial point of contact. Occasionally, viruses can utilize lipids as viral...

    Authors: Khursheed Muzammil, Mohammad Hosseini Hooshiar, Shirin Varmazyar, Thabit Moath Omar, Manal Morad Karim, Sadeq Aadi, Shaylan Kalavi and Saman Yasamineh
    Citation: Microbial Cell Factories 2024 23:90
  14. Staphylococcus aureus and its single or mixed biofilm infections seriously threaten global public health. Phage therapy, which uses active phage particles or phage-derived endolysins, has emerged as a promising a...

    Authors: He Liu, Xuemei Wei, Zhefen Wang, Xiaonan Huang, Mengyang Li, Zhen Hu, Kexin Zhang, Qiwen Hu, Huagang Peng, Weilong Shang, Yi Yang, Yuting Wang, Shuguang Lu and Xiancai Rao
    Citation: Microbial Cell Factories 2024 23:89
  15. The halophilic bacterium Halomonas elongata is an industrially important strain for ectoine production, with high value and intense research focus. While existing studies primarily delve into the adaptive mechani...

    Authors: Junxiong Yu, Yue Zhang, Hao Liu, Yuxuan Liu, Ali Mohsin, Zebo Liu, Yanning Zheng, Jianmin Xing, Jing Han, Yingping Zhuang, Meijin Guo and Zejian Wang
    Citation: Microbial Cell Factories 2024 23:88
  16. Natural tetramates are a family of hybrid polyketides bearing tetramic acid (pyrrolidine-2,4-dione) moiety exhibiting a broad range of bioactivities. Biosynthesis of tetramates in microorganisms is normally di...

    Authors: Haixia Zang, Yijia Cheng, Mengjia Li, Lin Zhou, Li-Li Hong, Hai Deng, Hou-Wen Lin and Yongjun Zhou
    Citation: Microbial Cell Factories 2024 23:87
  17. Escherichia coli is one of the most commonly used host organisms for the production of biopharmaceuticals, as it allows for cost-efficient and fast recombinant protein expression. However, challenging proteins ar...

    Authors: Christoph Köppl, Wolfgang Buchinger, Gerald Striedner and Monika Cserjan-Puschmann
    Citation: Microbial Cell Factories 2024 23:86
  18. The abundance of glucuronoxylan (GX) in agricultural and forestry residual side streams positions it as a promising feedstock for microbial conversion into valuable compounds. By engineering strains of the wid...

    Authors: Jonas L. Ravn, João H.C. Manfrão-Netto, Jana B. Schaubeder, Luca Torello Pianale, Stefan Spirk, Iván F. Ciklic and Cecilia Geijer
    Citation: Microbial Cell Factories 2024 23:85
  19. Extreme halophilic archaea that can live in high saline environments can offer potential applications in different biotechnological fields. This study delves into the fascinating field of halophilic archaea an...

    Authors: Basma T. Alghamrawy, Ghada E. Hegazy, Soraya A. Sabry and Hanan Ghozlan
    Citation: Microbial Cell Factories 2024 23:84
  20. Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant soluble protein in nature. Extensive studies have been conducted for improving its activity in photosynthesis through approaches l...

    Authors: Muhammad Faisal, Aditya P. Sarnaik, Nandini Kannoju, Nima Hajinajaf, Muhammad Javaid Asad, Ryan W. Davis and Arul M. Varman
    Citation: Microbial Cell Factories 2024 23:83
  21. Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, posing a serious public health challenge that necessitates the development of new therapeutics, therapies, and prevention methods. Among t...

    Authors: Rafał Jastrząb, Rafał Tomecki, Aneta Jurkiewicz, Damian Graczyk, Agnieszka K. Szczepankowska, Jennifer Mytych, Damian Wolman and Pawel Siedlecki
    Citation: Microbial Cell Factories 2024 23:82
  22. One of the leading current trends in technology is the miniaturization of devices to the microscale and nanoscale. The highly advanced approaches are based on biological systems, subjected to bioengineering us...

    Authors: Joanna Żebrowska, Piotr Mucha, Maciej Prusinowski, Daria Krefft, Agnieszka Żylicz-Stachula, Milena Deptuła, Aneta Skoniecka, Agata Tymińska, Małgorzata Zawrzykraj, Jacek Zieliński, Michał Pikuła and Piotr M. Skowron
    Citation: Microbial Cell Factories 2024 23:81
  23. Spathaspora passalidarum is a yeast with the highly effective capability of fermenting several monosaccharides in lignocellulosic hydrolysates, especially xylose. However, this yeast was shown to be sensitive to ...

    Authors: Thanyalak Saengphing, Pachara Sattayawat, Thitisuda Kalawil, Nakarin Suwannarach, Jaturong Kumla, Mamoru Yamada, Watanalai Panbangred and Nadchanok Rodrussamee
    Citation: Microbial Cell Factories 2024 23:80
  24. The current study aimed to evaluate the effects of biogenic silver nanoparticles (AgNPs) on growth behavior and leaf anatomy of in vitro growing shoots of ‘Picual’ and ‘Dolce’ olive cultivars. Biosynthesis of ...

    Authors: Mohamed S. Hasanin, Sayed A.M. Hassan, A. M. AbdAllatif and Osama M. Darwesh
    Citation: Microbial Cell Factories 2024 23:79
  25. The biosynthetic potency of Taxol by fungi raises their prospective to be a platform for commercial production of Taxol, nevertheless, the attenuation of its productivity with the fungal storage, is the challe...

    Authors: Asmaa Gamal, Eman Fikry, Nora Tawfeek, Azza M. El-Shafae, Ashraf S. A. El-Sayed and Maher M. El-Domiaty
    Citation: Microbial Cell Factories 2024 23:78
  26. Erythritol is a four-carbon polyol with an unclear role in metabolism of some unconventional yeasts. Its production has been linked to the osmotic stress response, but the mechanism of stress protection remain...

    Authors: DA. Rzechonek, M. Szczepańczyk, I. Borodina, C. Neuvéglise and AM. Mirończuk
    Citation: Microbial Cell Factories 2024 23:77
  27. Aspergillus niger ATCC 20611 is an industrially important fructooligosaccharides (FOS) producer since it produces the β-fructofuranosidase with superior transglycosylation activity, which is responsible for the c...

    Authors: Xiufen Wan, Lu Wang, Jingjing Chang, Jing Zhang, Zhiyun Zhang, Kewen Li, Guilian Sun, Caixia Liu and Yaohua Zhong
    Citation: Microbial Cell Factories 2024 23:76
  28. Lactic acid bacteria are commonly used as protective starter cultures in food products. Among their beneficial effects is the production of ribosomally synthesized peptides termed bacteriocins that kill or inh...

    Authors: Valentin Steier, Lisa Prigolovkin, Alexander Reiter, Tobias Neddermann, Wolfgang Wiechert, Sebastian J. Reich, Christian U. Riedel and Marco Oldiges
    Citation: Microbial Cell Factories 2024 23:74
  29. Lignocellulosic biomass provides a great starting point for the production of energy, chemicals, and fuels. The major component of lignocellulosic biomass is cellulose, the employment of highly effective enzym...

    Authors: Doaa A. Goda, Huda M. Shakam, Mai E. Metwally, Hager A. Abdelrasoul and Mohamed M. Yacout
    Citation: Microbial Cell Factories 2024 23:73

    The Correction to this article has been published in Microbial Cell Factories 2024 23:136

  30. Bacterial surface glycans are assembled by glycosyltransferases (GTs) that transfer sugar monomers to long-chained lipid carriers. Most bacteria employ the 55-carbon chain undecaprenyl phosphate (Und-P) to sca...

    Authors: Emily J. Kay, Manoj K. Dooda, Joseph C. Bryant, Amanda J. Reid, Brendan W. Wren, Jerry M. Troutman and Matthew A. Jorgenson
    Citation: Microbial Cell Factories 2024 23:72
  31. The improvement of yeast tolerance to acetic, butyric, and octanoic acids is an important step for the implementation of economically and technologically sustainable bioprocesses for the bioconversion of renew...

    Authors: Marta N. Mota, Madalena Matos, Nada Bahri and Isabel Sá-Correia
    Citation: Microbial Cell Factories 2024 23:71

    The Correction to this article has been published in Microbial Cell Factories 2024 23:176

  32. We report the successful fabrication of a pharmaceutical cellular bank (PCB) containing magnetotactic bacteria (MTB), which belong to the Magnetospirillum gryphiswaldense MSR1 species. To produce such PCB, we amp...

    Authors: Théo Chades, Raphaël Le Fèvre, Imène Chebbi, Karine Blondeau, François Guyot and Edouard Alphandéry
    Citation: Microbial Cell Factories 2024 23:70
  33. We are interested in converting second generation feedstocks into styrene, a valuable chemical compound, using the solvent-tolerant Pseudomonas putida DOT-T1E as a chassis. Styrene biosynthesis takes place from L...

    Authors: Ana García-Franco, Patricia Godoy, Estrella Duque and Juan L. Ramos
    Citation: Microbial Cell Factories 2024 23:69
  34. Owing to the growing need for natural materials in different fields, studying melanin production from biological sources is imperative. In the current study, the extracellular melanin pigment was produced by t...

    Authors: Amira S. Abd-EL-Aziz, Nermine N. Abed, Amira Y. Mahfouz and Rasha Mohammad Fathy
    Citation: Microbial Cell Factories 2024 23:68
  35. In recent years, the production of inclusion bodies that retain substantial catalytic activity was demonstrated. These catalytically active inclusion bodies (CatIBs) are formed by genetic fusion of an aggregat...

    Authors: Laura Marie Helleckes, Kira Küsters, Christian Wagner, Rebecca Hamel, Ronja Saborowski, Jan Marienhagen, Wolfgang Wiechert and Marco Oldiges
    Citation: Microbial Cell Factories 2024 23:67
  36. Komagataella phaffii (a.k.a. Pichia pastoris) harbors a glutamate utilization pathway in which synthesis of glutamate dehydrogenase 2 and phosphoenolpyruvate carboxykinase (PEPCK) is induced by glutamate. Glutama...

    Authors: Neetu Rajak, Trishna Dey, Yash Sharma, Vedanth Bellad and Pundi N. Rangarajan
    Citation: Microbial Cell Factories 2024 23:66
  37. Flavokawain B is one of the naturally occurring chalcones in the kava plant (Piper methysticum). It exhibits anticancer, anti-inflammatory and antimalarial properties. Due to its therapeutic potential, flavokawai...

    Authors: Paweł Chlipała, Tomasz Tronina, Monika Dymarska, Monika Urbaniak, Ewa Kozłowska, Łukasz Stępień, Edyta Kostrzewa-Susłow and Tomasz Janeczko
    Citation: Microbial Cell Factories 2024 23:65
  38. Phosphate solubilizing fungi Penicillium oxalicum (POX) and Red yeast Rhodotorula mucilaginosa (Rho) have been applied in Pb remediation with the combination of fluorapatite (FAp), respectively. The secretion of ...

    Authors: Qiang Guan, Xiaohui Cheng, Yue He, Yifan Yan, Lei Zhang, Zhan Wang, Liangliang Zhang and Da Tian
    Citation: Microbial Cell Factories 2024 23:64
  39. Yeasts exhibit promising potential for the microbial conversion of crude glycerol, owing to their versatility in delivering a wide range of value-added products, particularly lipids. Sweetwater, a methanol-fre...

    Authors: Valériane Malika Keita, Yi Qing Lee, Meiyappan Lakshmanan, Dave Siak-Wei Ow, Paul Staniland, Jessica Staniland, Ian Savill, Kang Lan Tee, Tuck Seng Wong and Dong-Yup Lee
    Citation: Microbial Cell Factories 2024 23:63
  40. 1,2-propanediol (1,2-PDO) is widely used in the cosmetic, food, and drug industries with a worldwide consumption of over 1.5 million metric tons per year. Although efforts have been made to engineer microbial ...

    Authors: Daniel Siebert, Erich Glawischnig, Marie-Theres Wirth, Mieke Vannahme, Álvaro Salazar-Quirós, Annette Weiske, Ezgi Saydam, Dominik Möggenried, Volker F. Wendisch and Bastian Blombach
    Citation: Microbial Cell Factories 2024 23:62
  41. Helicobacter pylori (H. pylori) causes chronic gastric disease. An efficient oral vaccine would be mucosa-targeted and offer defense against colonization of invasive infection in the digestive system. Proteolytic...

    Authors: Furui Zhang, Linhan Ni, Zhen Zhang, Xuegang Luo, Xuequan Wang, Wenmiao Zhou, Jiale Chen, Jing Liu, Yuliang Qu, Kunmei Liu and Le Guo
    Citation: Microbial Cell Factories 2024 23:61
  42. The marine black yeasts are characterized by the production of many novel protective substances. These compounds increase their physiological adaptation to multi-extreme environmental stress. Hence, the exopol...

    Authors: Eman H. Zaghloul, Hala H. Abdel-Latif, Asmaa Elsayis and Sahar W.M. Hassan
    Citation: Microbial Cell Factories 2024 23:60
  43. Polyhydroxybutyrate is a biopolymer produced by bacteria and archaea under nitrogen-limiting conditions. PHB is an essential polymer in the bioplastic sector because of its biodegradability, eco-friendliness, ...

    Authors: Teja Mandragutti, Tura Safawo Jarso, Sudhakar Godi, S Sharmila Begum and Beulah K
    Citation: Microbial Cell Factories 2024 23:59
  44. Acetoin, a versatile platform chemical and popular food additive, poses a challenge to the biosafety strain Bacillus subtilis when produced in high concentrations due to its intrinsic toxicity. Incorporating the ...

    Authors: Tao Li, Haixiang Li, Lei Zhong, Yufei Qin, Gege Guo, Zhaoxing Liu, Ning Hao and Pingkai Ouyang
    Citation: Microbial Cell Factories 2024 23:58
  45. Polyhydroxybutyrate (PHB) has emerged as a promising eco-friendly alternative to traditional petrochemical-based plastics. In the present study, we isolated and characterized a new strain of Salinicola salarius, ...

    Authors: Shymaa A. Abdelrahman, Olfat S. Barakat and Marwa N. Ahmed
    Citation: Microbial Cell Factories 2024 23:56
  46. Pichia pastoris is a widely utilized host for heterologous protein expression and biotransformation. Despite the numerous strategies developed to optimize the chassis host GS115, the potential impact of changes i...

    Authors: Bingjie Cheng, Keyang Yu, Xing Weng, Zhaojun Liu, Xuewu Huang, Yuhong Jiang, Shuai Zhang, Shuyan Wu, Xiaoyuan Wang and Xiaoqing Hu
    Citation: Microbial Cell Factories 2024 23:55

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