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  1. Neutralizing antibody plays a key role in protecting hosts from invasive pathogens and their virulent components. Current high-throughput assays for antibody screening are based on binding activities. However,...

    Authors: Ying Sun, Yongrong Zhang, Hua Yu, Ashley Saint Fleur, Di Yu, Zhiyong Yang and Hanping Feng
    Citation: Microbial Cell Factories 2023 22:194
  2. Microbial degradation of synthetic dyes is considered a promising green dye detoxification, cost-effective and eco-friendly approach. A detailed study on the decolorization and degradation of malachite green d...

    Authors: Magda A. El-Bendary, Mariam E. Fawzy, Mohamed Abdelraof, Mervat El-Sedik and Mousa A. Allam
    Citation: Microbial Cell Factories 2023 22:192
  3. Fatty acid (FA) is an important platform compound for the further synthesis of high‐value biofuels and oleochemicals, but chemical synthesis of FA has many limitations. One way to meet the future demand for FA...

    Authors: Jin Liu, Mandlaa, Jia Wang, Ziyu Sun and Zhongjun Chen
    Citation: Microbial Cell Factories 2023 22:191
  4. Hydrogen is a promising source of alternative energy. Fermentative production is more feasible because of its high hydrogen generation rate, simple operating conditions, and utilization of various organic wast...

    Authors: Eman S. E. Aldaby, Aya H. A. Mahmoud, Haitham M. El-Bery, Maysa M. Ali, Ahmed A. Shoreit and Asmaa M. M. Mawad
    Citation: Microbial Cell Factories 2023 22:190
  5. Plastics are an indispensable part of our daily life. However, mismanagement at their end-of-life results in severe environmental consequences. The microbial conversion of these polymers into new value-added p...

    Authors: Tom Delmulle, Stijn Bovijn, Sari Deketelaere, Martijn Castelein, Tom Erauw, Matthias D’hooghe and Wim K. Soetaert
    Citation: Microbial Cell Factories 2023 22:188
  6. Enzymes from thermophiles are of great interest for research and bioengineering due to their stability and efficiency. Thermophilic expression hosts such as Thermus thermophilus [T. thermophilus] can overcome spe...

    Authors: Lennart Kirchner, Volker Müller and Beate Averhoff
    Citation: Microbial Cell Factories 2023 22:187
  7. The budding yeast Saccharomyces cerevisiae (S. cerevisiae) is a well-established model system for studying protein aggregation due to the conservation of essential cellular structures and pathways found across eu...

    Authors: Javier Garcia-Pardo, Aleksandra E. Badaczewska-Dawid, Carlos Pintado-Grima, Valentín Iglesias, Aleksander Kuriata, Sebastian Kmiecik and Salvador Ventura
    Citation: Microbial Cell Factories 2023 22:186
  8. In the recombinant protein market with broad economic value, the rapid development of synthetic biology has made it necessary to construct an efficient exocrine expression system for the different heterologous...

    Authors: Siqian Yu, Ge Zhang, Qi Liu, Yingping Zhuang, Zongjie Dai and Jianye Xia
    Citation: Microbial Cell Factories 2023 22:185
  9. Bioplastics are attracting considerable attention, owing to the increase in non-degradable waste. Using microorganisms to degrade bioplastics is a promising strategy for reducing non-degradable plastic waste. ...

    Authors: Su Hyun Kim, Nara Shin, Suk Jin Oh, Jeong Hyeon Hwang, Hyun Jin Kim, Shashi Kant Bhatia, Jeonghee Yun, Jae-Seok Kim and Yung-Hun Yang
    Citation: Microbial Cell Factories 2023 22:184
  10. Microbial fuel cell (MFC) is a bio-electrical energy generator that uses respiring microbes to transform organic matter present in sludge into electrical energy. The primary goal of this work was to introduce ...

    Authors: Amal S. Othman, Nashwa A. Ahmed, Mona S. Elneklawi, Mansour M. Hassan and Mahmoud Abd El-Mongy
    Citation: Microbial Cell Factories 2023 22:183
  11. In the post-genomic era, the demand for faster and more efficient protein production has increased, both in public laboratories and industry. In addition, with the expansion of protein sequences in databases, ...

    Authors: Manman Sun, Alex Xiong Gao, Xiuxia Liu, Yankun Yang, Rodrigo Ledesma-Amaro and Zhonghu Bai
    Citation: Microbial Cell Factories 2023 22:182
  12. The advantages of γ-cyclodextrin (γ-CD) include its high solubility, ability to form inclusion complexes with various poorly water-soluble molecules, and favorable toxicological profile; thus, γ-CD is an attra...

    Authors: Menglu Duan, Yan Wang, Dan Tan, Guowu Yang, Yuan Deng, Ganqiao Ran and Jiao Li
    Citation: Microbial Cell Factories 2023 22:181
  13. Saccharomyces cerevisiae has been used in the biosynthesis of acid products such as organic acids owing to its acid tolerance. Improving the acid tolerance of S. cerevisiae is beneficial for expanding its applica...

    Authors: Xueqin Lv, Ke Jin, Yu Yi, Lingang Song, Xiang Xiu, Yanfeng Liu, Jianghua Li, Guocheng Du, Jian Chen and Long Liu
    Citation: Microbial Cell Factories 2023 22:180
  14. Alginate oligosaccharides (AOs) are the degradation products of alginate, a natural polysaccharide abundant in brown algae. AOs generated by enzymatic hydrolysis have diverse bioactivities and show broad appli...

    Authors: Xiao-Hui Sun, Xiu-Lan Chen, Xiao-Fei Wang, Xin-Ru Zhang, Xiao-Meng Sun, Mei-Ling Sun, Xi-Ying Zhang, Yu-Zhong Zhang, Yu-Qiang Zhang and Fei Xu
    Citation: Microbial Cell Factories 2023 22:179
  15. γ-aminobutyric acid (GABA) is a bioactive compound produced by lactic acid bacteria (LAB). The diversity of GABA production in the Lactococcus genus is poorly understood. Genotypic and phenotypic approaches were ...

    Authors: Valérie Laroute, Nathalie Aubry, Marjorie Audonnet, Muriel Mercier-Bonin, Marie-Line Daveran-Mingot and Muriel Cocaign-Bousquet
    Citation: Microbial Cell Factories 2023 22:178
  16. Avian pathogenic Escherichia coli (APEC) is the major pathogen causing important avian diseases in poultry. As an important subtype of extraintestinal pathogenic E. coli, APEC has zoonotic potential and is consid...

    Authors: Zhongxing Wang, Dongyu Zhu, Yuting Zhang, Fufang Xia, Jiaying Zhu, Jianjun Dai and Xiangkai Zhuge
    Citation: Microbial Cell Factories 2023 22:177
  17. Bioemulsifiers are natural or microbial-based products with the ability to emulsify hydrophobic compounds in water. These compounds are biodegradable, eco-friendly, and find applications in various industries.

    Authors: Yasmina A. Elsaygh, Mona K. Gouda, Yasser Elbahloul, Moustafa Abdel Hakim and Nancy M. El Halfawy
    Citation: Microbial Cell Factories 2023 22:176
  18. Adaptive laboratory evolution (ALE) is known as a powerful tool for untargeted engineering of microbial strains and genomics research. It is particularly well suited for the adaptation of microorganisms to new...

    Authors: Lars Halle, Niels Hollmann, Niklas Tenhaef, Lea Mbengi, Christiane Glitz, Wolfgang Wiechert, Tino Polen, Meike Baumgart, Michael Bott and Stephan Noack
    Citation: Microbial Cell Factories 2023 22:175
  19. Surface display co-opts yeast’s innate ability to embellish its cell wall with mannoproteins, thus converting the yeast’s outer surface into a growing and self-sustaining catalyst. However, the efficient toolb...

    Authors: Tea Martinić Cezar, Mateja Lozančić, Ana Novačić, Ana Matičević, Dominik Matijević, Béatrice Vallée, Vladimir Mrša, Renata Teparić and Bojan Žunar
    Citation: Microbial Cell Factories 2023 22:174
  20. Marine macroalgae have gained interest recently, mostly due to their bioactive components. Polycladia crinita is an example of marine macroalgae from the Phaeophyceae class, also known as brown algae. They are ch...

    Authors: Alanood S. Almurshedi, Thanaa A. El-Masry, Hend Selim, Mostafa M. El-Sheekh, Mofida E. M. Makhlof, Basmah N. Aldosari, Iman M. Alfagih, Bushra T. AlQuadeib, Salma S. Almarshidy and Maisra M. El-Bouseary
    Citation: Microbial Cell Factories 2023 22:173
  21. Pyruvate is a widely used value-added chemical which also serves as a hub of various metabolic pathways. The fastest-growing bacterium Vibrio natriegens is a promising chassis for synthetic biology applications w...

    Authors: Fengli Wu, Shucai Wang, Yanfeng Peng, Yufeng Guo and Qinhong Wang
    Citation: Microbial Cell Factories 2023 22:172
  22. Polyhydroxyalkanoate (PHA) is one of the most promising materials for replacing petroleum-based plastics, and it can be produced from various renewable biomass sources. In this study, PHA production was conduc...

    Authors: Yerin Park, Jong-Min Jeon, Jea-Kyung Park, Yung-Hun Yang, Shin Sik Choi and Jeong-Jun Yoon
    Citation: Microbial Cell Factories 2023 22:171
  23. Oro-gastrointestinal stress in the digestive tract is the main stress to which orally administered probiotics are exposed. The regulation of oro-gastrointestinal transit (OGT) stress on the adhesion and surviv...

    Authors: Dawei Chen, Chunmeng Chen, Congcong Guo, Hui Zhang, Yating Liang, Yue Cheng, Hengxian Qu, Yunchao Wa, Chenchen Zhang, Chengran Guan, Jianya Qian and Ruixia Gu
    Citation: Microbial Cell Factories 2023 22:170
  24. Endophytes, especially those isolated from herbal plants, may act as a reservoir of a variety of secondary metabolites exhibiting biological activity. Some endophytes express the ability to produce the same bi...

    Authors: Olga Marchut-Mikołajczyk, Magdalena Chlebicz, Monika Kawecka, Agnieszka Michalak, Filip Prucnal, Maciej Nielipinski, Jakub Filipek, Michalina Jankowska, Zofia Perek, Piotr Drożdżyński, Natalia Rutkowska and Anna Otlewska
    Citation: Microbial Cell Factories 2023 22:169
  25. Microbial production of aromatic chemicals is an attractive method for obtaining high-performance materials from biomass resources. A non-proteinogenic amino acid, 4-amino-3-hydroxybenzoic acid (4,3-AHBA), is ...

    Authors: Kyoshiro Nonaka, Tatsuya Osamura and Fumikazu Takahashi
    Citation: Microbial Cell Factories 2023 22:168
  26. Pyocyanin is a secondary metabolite secreted by P. aeruginosa. It is a redox-active blue/green phenazine pigment that has various beneficial applications. The present study aims at screening the production of pyo...

    Authors: Heba Shouman, Heba Shehta Said, Hany I. Kenawy and Ramadan Hassan
    Citation: Microbial Cell Factories 2023 22:166
  27. 3-Hydroxybutanone (Acetoin, AC) and 2,3-butanediol (BD) are two essential four-carbon platform compounds with numerous pharmaceutical and chemical synthesis applications. AC and BD have two and three stereoiso...

    Authors: Yuchen Li, Xiangying Zhao, Mingjing Yao, Wenli Yang, Yanlei Han, Liping Liu, Jiaxiang Zhang and Jianjun Liu
    Citation: Microbial Cell Factories 2023 22:165
  28. Recently, researchers have focused on the search for alternatives to conventional antibiotics. Antimicrobial peptides are small bioactive peptides that regulate immune activation and have antibacterial activit...

    Authors: Chunming Dong, Lijun Xu, Weitao Lu, Mengru Li, Rui Zhang, Yanyan Sun, Jian Liu and Xinlei Chu
    Citation: Microbial Cell Factories 2023 22:164
  29. Poly-β-hydroxybutyrate (PHB), produced by a variety of microbial organisms, is a good substitute for petrochemically derived plastics due to its excellent properties such as biocompatibility and biodegradabili...

    Authors: Yue Ming, Guoqiang Li, Zhuangzhuang Shi, Xin Zhao, Yufei Zhao, Ge Gao, Ting Ma and Mengmeng Wu
    Citation: Microbial Cell Factories 2023 22:162
  30. The non-conventional yeast Rhodotorula toruloides is an emerging host organism in biotechnology by merit of its natural capacity to accumulate high levels of carotenoids and intracellular storage lipids from a va...

    Authors: Daniel P. Brink, Friederike Mierke, Joakim Norbeck, Verena Siewers and Thomas Andlid
    Citation: Microbial Cell Factories 2023 22:160
  31. Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine ...

    Authors: Sherif Abouelhadid, Elizabeth R. Atkins, Emily J. Kay, Ian J. Passmore, Simon J. North, Burhan Lehri, Paul Hitchen, Eirik Bakke, Mohammed Rahman, Janine T. Bossé, Yanwen Li, Vanessa S. Terra, Paul R. Langford, Anne Dell, Brendan W. Wren and Jon Cuccui
    Citation: Microbial Cell Factories 2023 22:159
  32. During the production of L-arginine through high dissolved oxygen and nitrogen supply fermentation, the industrial workhorse Corynebacterium glutamicum is exposed to oxidative stress. This generates reactive oxyg...

    Authors: Ziqin Jiang, Jingyi Guan, Tingting Liu, Chunyu Shangguan, Meijuan Xu and Zhiming Rao
    Citation: Microbial Cell Factories 2023 22:158
  33. New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic chemical pesticides and to combat growing levels of pest...

    Authors: Jake S. De-Thier, Prashant Pyati, Jack Bell, Jennifer J. Readshaw, Adrian P. Brown and Elaine C. Fitches
    Citation: Microbial Cell Factories 2023 22:157
  34. Sm1 and Chit42 of Trichoderma have been universally confirmed as crucial biocontrol factors against pathogen infection through induced resistance and mycoparasitism, respectively. However, not enough work has bee...

    Authors: Hongyi Liu, Shaoqing Wang, Bo Lang, Yaqian Li, Xinhua Wang and Jie Chen
    Citation: Microbial Cell Factories 2023 22:156
  35. Yarrowia lipolytica is a dimorphic fungus, which switches from yeast to filament form in response to environmental conditions. For industrial purposes it is important to lock cells in the yeast or filamentous for...

    Authors: Dorota A. Rzechonek, Mateusz Szczepańczyk and Aleksandra M. Mirończuk
    Citation: Microbial Cell Factories 2023 22:155
  36. Using fungal biomass for biocatalysis is a potential solution for the expensive cost of the use o enzymes. Production of fungal biomass with effective activity requires optimizing the cultivation conditions.

    Authors: Nadeem I. Elhussieny, Heba A. El-Refai, Sayeda S. Mohamed, Yousseria M. Shetaia, Hala A. Amin and Gerd Klöck
    Citation: Microbial Cell Factories 2023 22:154
  37. The omnipresence of population heterogeneity in industrial bioprocesses originates from prevailing dynamic bioprocess conditions, which promote differences in the expression of cellular characteristics. Despit...

    Authors: Manh Dat Hoang, Ingmar Polte, Lukas Frantzmann, Nikolas von den Eichen, Anna-Lena Heins and Dirk Weuster-Botz
    Citation: Microbial Cell Factories 2023 22:153
  38. Despite being necessary, copper is a toxic heavy metal that, at high concentrations, harms the life system. The parameters that affect the bioreduction and biosorption of copper are highly copper-resistant bac...

    Authors: Amal William Danial and Fatma Mohamed Dardir
    Citation: Microbial Cell Factories 2023 22:152
  39. Methionine is an essential amino acid in mammals and a precursor for vital metabolites required for the survival of all organisms. Consequently, its inclusion is required in diverse applications, such as food,...

    Authors: Nadya Gruzdev, Yael Hacham, Hadar Haviv, Inbar Stern, Matan Gabay, Itai Bloch, Rachel Amir, Maayan Gal and Itamar Yadid
    Citation: Microbial Cell Factories 2023 22:151
  40. Glucoamylase is an important enzyme for starch saccharification in the food and biofuel industries and mainly produced from mesophilic fungi such as Aspergillus and Rhizopus species. Enzymes produced from thermop...

    Authors: Zhijian Zhu, Manyu Zhang, Dandan Liu, Defei Liu, Tao Sun, Yujing Yang, Jiacheng Dong, Huanhuan Zhai, Wenliang Sun, Qian Liu and Chaoguang Tian
    Citation: Microbial Cell Factories 2023 22:150
  41. Lanthipeptides are a rapidly expanding family of ribosomally synthesized and post-translationally modified natural compounds with diverse biological functions. Lanthipeptide structural and biosynthetic genes c...

    Authors: Winschau F Van Zyl, Anton D. Van Staden, Leon M T. Dicks and Marla Trindade
    Citation: Microbial Cell Factories 2023 22:149
  42. Colorectal cancer (CRC) is the third cause of death by cancers worldwide and is one of the most common cancer types reported in both Egypt and the United States. The use of probiotics as a dietary therapy is i...

    Authors: Gaber A. Abo-Zaid, Ahmed M. Kenawy, Nehal M. El-Deeb and Lamiaa A. Al-Madboly
    Citation: Microbial Cell Factories 2023 22:148
  43. Vanillin (4-hydroxy-3-methoxybenzaldehyde) is one of the most popular flavors with wide applications in food, fragrance, and pharmaceutical industries. However, the high cost and limited yield of plant extract...

    Authors: Ying Liu, Lichao Sun, Yi-Xin Huo and Shuyuan Guo
    Citation: Microbial Cell Factories 2023 22:147
  44. Authors: Beata Łubkowska, Edyta Czajkowska, Aleksandra Stodolna, Michał Sroczyński, Agnieszka Zylicz-Stachula, Ireneusz Sobolewski and Piotr M. Skowron
    Citation: Microbial Cell Factories 2023 22:146

    The original article was published in Microbial Cell Factories 2023 22:80

  45. R. toruloides is an oleaginous yeast, with diverse metabolic capacities and high tolerance for inhibitory compounds abundant in plant biomass hydrolysates. While R. toruloides grows on several pentose sugars and ...

    Authors: Paul A. Adamczyk, Samuel T. Coradetti and John M. Gladden
    Citation: Microbial Cell Factories 2023 22:145
  46. Efficient conversion of pentose sugars remains a significant barrier to the replacement of petroleum-derived chemicals with plant biomass-derived bioproducts. While the oleaginous yeast Rhodosporidium toruloides ...

    Authors: Samuel T. Coradetti, Paul A. Adamczyk, Di Liu, Yuqian Gao, Peter B. Otoupal, Gina M. Geiselman, Bobbie-Jo M. Webb-Robertson, Meagan C. Burnet, Young-Mo Kim, Kristin E. Burnum-Johnson, Jon Magnuson and John M. Gladden
    Citation: Microbial Cell Factories 2023 22:144

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