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  1. The 5´ untranslated region (5´ UTR) plays a key role in regulating translation efficiency and mRNA stability, making it a favored target in genetic engineering and synthetic biology. A common feature found in ...

    Authors: Junyuan Zeng, Kunfeng Song, Jingqi Wang, Haimei Wen, Jungang Zhou, Ting Ni, Hong Lu and Yao Yu
    Citation: Microbial Cell Factories 2024 23:7
  2. Transforming waste and nonfood materials into bulk biofuels and chemicals represents a major stride in creating a sustainable bioindustry to optimize the use of resources while reducing environmental footprint...

    Authors: Kyoyoung Seo, Wei Shu, Christian Rückert-Reed, Patrick Gerlinger, Tobias J. Erb, Jörn Kalinowski and Christoph Wittmann
    Citation: Microbial Cell Factories 2023 22:262
  3. Monitoring and control of both growth media and microbial biomass is extremely important for the development of economical bioprocesses. Unfortunately, process monitoring is still dependent on a limited number...

    Authors: Simona Dzurendova, Pernille Margrethe Olsen, Dana Byrtusová, Valeria Tafintseva, Volha Shapaval, Svein Jarle Horn, Achim Kohler, Martin Szotkowski, Ivana Marova and Boris Zimmermann
    Citation: Microbial Cell Factories 2023 22:261
  4. RNA-dependent RNA polymerase (RdRp) is a good target of anti-RNA virus agents; not only it is pivotal for the RNA virus replication cycle and highly conserved among RNA viruses across different families, but a...

    Authors: Kantaphon Glab-ampai, Kodchakorn Mahasongkram, Monrat Chulanetra, Thanatsaran Saenlom, Kanyarat Thueng-in, Nitat Sookrung and Wanpen Chaicumpa
    Citation: Microbial Cell Factories 2023 22:260
  5. Komagataella phaffii (Pichia pastoris) is a methylotrophic commercially important non-conventional species of yeast that grows in a fermentor to exceptionally high densities on simple media and secretes recombina...

    Authors: Dariusz Abramczyk, Maria del Carmen Sanchez Olmos, Adan Andres Ramirez Rojas, Daniel Schindler, Daniel Robertson, Stephen McColm, Adele L. Marston and Paul N. Barlow
    Citation: Microbial Cell Factories 2023 22:259
  6. Color chemicals contaminate pure water constantly discharged from different points and non-point sources. Physical and chemical techniques have certain limitations and complexities for bioenergy production, wh...

    Authors: Aisha Umar, Islem Abid, Mohammed Antar, Laurent Dufossé, Lobna Hajji-Hedfi, Mohamed S. Elshikh, Abeer El Shahawy and Ahmed M. Abdel-Azeem
    Citation: Microbial Cell Factories 2023 22:258
  7. Streptomyces lincolnensis is well known for producing the clinically important antimicrobial agent lincomycin. The synthetic and regulatory mechanisms on lincomycin biosynthesis have been deeply explored in recen...

    Authors: Chun-Yan Lin, Yixian Ru, Yanchao Jin, Qi Lin and Guang-Rong Zhao
    Citation: Microbial Cell Factories 2023 22:257
  8. Gamma-aminobutyric acid (GABA) is a non-protein amino acid with neuroinhibitory, antidiabetic, and antihypertensive properties and is used as a drug for treating anxiety and depression. Some strains of lactoba...

    Authors: Sumanpreet Kaur, Preeti Sharma, Melinda J. Mayer, Saskia Neuert, Arjan Narbad and Sukhraj Kaur
    Citation: Microbial Cell Factories 2023 22:256
  9. Uridyl peptide compounds are renowned as a subclass of nucleoside antibiotics for their highly specific antibacterial activity against Gram-negative bacteria and the unique target of action. We previously acti...

    Authors: Ning Liu, Yang Xu, Fei Shang, Huiying Sun, Xiang Liu, Ying Huang, Huarong Tan and Jihui Zhang
    Citation: Microbial Cell Factories 2023 22:255
  10. It is increasingly recognized that conventional food production systems are not able to meet the globally increasing protein needs, resulting in overexploitation and depletion of resources, and environmental d...

    Authors: Myrsini Sakarika, Frederiek-Maarten Kerckhof, Lotte Van Peteghem, Alexandra Pereira, Tim Van Den Bossche, Robbin Bouwmeester, Ralf Gabriels, Delphi Van Haver, Barbara Ulčar, Lennart Martens, Francis Impens, Nico Boon, Ramon Ganigué and Korneel Rabaey
    Citation: Microbial Cell Factories 2023 22:254
  11. Cordycepin (3′-deoxyadenosine) is an important bioactive compound in medical and healthcare markets. The drawbacks of commercial cordycepin production using Cordyceps spp. include long cultivation periods and low...

    Authors: Sukanya Jeennor, Jutamas Anantayanon, Sarocha Panchanawaporn, Chanikul Chutrakul, Wanwipa Vongsangnak and Kobkul Laoteng
    Citation: Microbial Cell Factories 2023 22:253
  12. Pectinase is a particular type of enzyme that can break down pectin compounds and is extensively utilised in the agricultural field. In this study, twenty yeast isolates were isolated and assayed for pectinase...

    Authors: Nagwa M. Abd El-Aziz, Maysa E. Moharam, Nora N. El-Gamal and Bigad E. Khalil
    Citation: Microbial Cell Factories 2023 22:252
  13. In yeast, recombinant membrane proteins including viral scaffold proteins used for the formation of enveloped Virus-like particles (eVLPs) typically accumulate intracellularly. Their recovery is carried out by...

    Authors: Valentina Ganeva and Andreas Kranz
    Citation: Microbial Cell Factories 2023 22:251
  14. Identifying individual characteristics based on trace evidence left at a crime scene is crucial in forensic identification. Microbial communities found in fecal traces have high individual specificity and coul...

    Authors: Yu Liang, Shujie Dou, Guangzhong Zhao, Jie Shen, Guangping Fu, Lihong Fu, Shujin Li, Bin Cong and Chunnan Dong
    Citation: Microbial Cell Factories 2023 22:250
  15. Authors: Ernesta Augustiniene, Ilona Jonuskiene, Jurgita Kailiuviene, Edita Mazoniene, Kestutis Baltakys and Naglis Malys
    Citation: Microbial Cell Factories 2023 22:249

    The original article was published in Microbial Cell Factories 2023 22:223

  16. Intracellular hyperaccumulation of phycocyanin (PC) and its high susceptibility to degradation at higher temperatures are major challenging problems associated with its production from cyanobacteria. The prese...

    Authors: Mohamed Gomaa, Shimaa Abdelmohsen Ali and Awatief F. Hifney
    Citation: Microbial Cell Factories 2023 22:248
  17. Photosynthetic cyanobacterial components are gaining great economic importance as prospective low-cost biostimulants for the green synthesis of metal nanoparticles with valuable medical and industrial applicat...

    Authors: Asmaa H. Al-Badwy, Ahmed M. Khalil, Ali H. Bashal and Rashad Kebeish
    Citation: Microbial Cell Factories 2023 22:247
  18. Biodiesel, unlike to its fossil-based homologue (diesel), is renewable. Its use contributes to greater sustainability in the energy sector, mainly by reducing greenhouse gas emissions. Current biodiesel produc...

    Authors: María Gallego-García, Ana Susmozas, María José Negro and Antonio D. Moreno
    Citation: Microbial Cell Factories 2023 22:246
  19. Removal of trace organic chemicals (TOrCs) in aquatic environments has been intensively studied. Some members of natural microbial communities play a vital role in transforming chemical contaminants, however, ...

    Authors: Lijia Cao, Sarahi L. Garcia and Christian Wurzbacher
    Citation: Microbial Cell Factories 2023 22:245
  20. Protein complex assembly facilitates the combination of individual protein subunits into functional entities, and thus plays a crucial role in biology and biotechnology. Recently, we developed quasi-twodimensi...

    Authors: Stefanie Förste, Ohad Vonshak, Shirley S. Daube, Roy H. Bar-Ziv, Reinhard Lipowsky and Sophia Rudorf
    Citation: Microbial Cell Factories 2023 22:244
  21. Integrated metabolic engineering approaches that combine system and synthetic biology tools enable the efficient design of microbial cell factories for synthesizing high-value products. In this study, we utili...

    Authors: Koray Malcı, Rodrigo Santibáñez, Nestor Jonguitud-Borrego, Jorge H. Santoyo-Garcia, Eduard J. Kerkhoven and Leonardo Rios-Solis
    Citation: Microbial Cell Factories 2023 22:243
  22. Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process....

    Authors: Mathias Gotsmy, Florian Strobl, Florian Weiß, Petra Gruber, Barbara Kraus, Juergen Mairhofer and Jürgen Zanghellini
    Citation: Microbial Cell Factories 2023 22:242
  23. In whole-cell bio-catalysis, the biosystems engineering paradigm shifts from the global reconfiguration of cellular metabolism as in fermentation to a more focused, and more easily modularized, optimization of...

    Authors: Sabine Schelch, Manuel Eibinger, Jasmin Zuson, Jürgen Kuballa and Bernd Nidetzky
    Citation: Microbial Cell Factories 2023 22:241
  24. trans-4-Hydroxyproline (T-4-HYP) is a promising intermediate in the synthesis of antibiotic drugs. However, its industrial production remains challenging due to the low production efficiency of T-4-HYP. This stud...

    Authors: Yu Gong, Ruiqi Wang, Ling Ma, Shuo Wang, Changgeng Li and Qingyang Xu
    Citation: Microbial Cell Factories 2023 22:240
  25. (Hydroxy)cinnamyl alcohols and allylphenols, including coniferyl alcohol and eugenol, are naturally occurring aromatic compounds widely utilised in pharmaceuticals, flavours, and fragrances. Traditionally, the...

    Authors: Erik K. R. Hanko, Kris Niño G. Valdehuesa, Koen J. A. Verhagen, Jakub Chromy, Ruth A. Stoney, Jeremy Chua, Cunyu Yan, Johannes A. Roubos, Joep Schmitz and Rainer Breitling
    Citation: Microbial Cell Factories 2023 22:238
  26. Methanol is increasingly gaining attraction as renewable carbon source to produce specialty and commodity chemicals, as it can be generated from renewable sources such as carbon dioxide (CO2). In this context, na...

    Authors: Sílvia Àvila-Cabré, Míriam Pérez-Trujillo, Joan Albiol and Pau Ferrer
    Citation: Microbial Cell Factories 2023 22:237
  27. Thermophilic fungus Myceliophthora thermophila has been widely used in industrial applications due to its ability to produce various enzymes. However, the lack of an efficient protein expression system has limite...

    Authors: Jinyang Li, Yidi Wang, Kun Yang, Xiaolu Wang, Yuan Wang, Honglian Zhang, Huoqing Huang, Xiaoyun Su, Bin Yao, Huiying Luo and Xing Qin
    Citation: Microbial Cell Factories 2023 22:236
  28. Emerging evidence has shown that extracellular vesicles (EVs) derived from gut bacteria play a crucial role in microbiota-host interactions. Here, we aimed to evaluate the attenuating effect of EVs derived fro...

    Authors: Lin Ye, Yizhong Wang, Fangfei Xiao, Xufei Wang, Xiaolu Li, Rong Cao, Jiayue Zhang and Ting Zhang
    Citation: Microbial Cell Factories 2023 22:235
  29. Flavonoids are important plant secondary metabolites showing antioxidant, antitumor, anti-inflammatory, and antiviral activities, among others. Methylated flavonoids are particularly interesting compared to no...

    Authors: Álvaro Pérez-Valero, Suhui Ye, Patricia Magadán-Corpas, Claudio J. Villar and Felipe Lombó
    Citation: Microbial Cell Factories 2023 22:234
  30. Pamamycins are a family of highly bioactive macrodiolide polyketides produced by Streptomyces alboniger as a complex mixture of derivatives with molecular weights ranging from 579 to 705 Daltons. The large deriva...

    Authors: Nikolas Eckert, Yuriy Rebets, Lilya Horbal, Josef Zapp, Jennifer Herrmann, Tobias Busche, Rolf Müller, Jörn Kalinowski and Andriy Luzhetskyy
    Citation: Microbial Cell Factories 2023 22:233
  31. Several reports demonstrated anti-inflammatory properties of minocycline in various inflammatory disorders including colitis. We have experimental evidence suggesting synergistic anti-inflammatory effect of mi...

    Authors: Maitham A. Khajah and Sanaa Hawai
    Citation: Microbial Cell Factories 2023 22:232
  32. The physical states and chemical components of bulk sludge determine the occurrence and development of membrane fouling in membrane bioreactors. Thus, regulation of sludge suspensions can provide new strategie...

    Authors: Ji Qi, Qicheng Zhou, Danlei Huang, Zhong Yu and Fangang Meng
    Citation: Microbial Cell Factories 2023 22:230
  33. Cyanobacteria are a potential source of promising secondary metabolites with different biological activities, including antibacterial, antiviral, antifungal, antiprotozoal, and anticancer activities. To combat...

    Authors: Mabroka H. Saad, Nagwa M. Sidkey and Esmail M. El-Fakharany
    Citation: Microbial Cell Factories 2023 22:229
  34. Mycosynthesis of silver nanoparticles (SNPs) offers a safe, eco-friendly, and promising alternative technique for large-scale manufacturing. Our study might be the first report that uses mycelial filtrate of a...

    Authors: Nessma A. EL-Zawawy, Alaa M. Abou-Zeid, Doha M. Beltagy, Nada H. Hantera and Hoda S. Nouh
    Citation: Microbial Cell Factories 2023 22:228
  35. Not changing the native constitution of genes prior to their expression by a heterologous host can affect the amount of proteins synthesized as well as their folding, hampering their activity and even cell via...

    Authors: Thomas Willems, Wim Hectors, Jeltien Rombaut, Anne-Sofie De Rop, Stijn Goegebeur, Tom Delmulle, Maarten L. De Mol, Sofie L. De Maeseneire and Wim K. Soetaert
    Citation: Microbial Cell Factories 2023 22:227
  36. Many plants possess immense pharmacological properties because of the presence of various therapeutic bioactive secondary metabolites that are of great importance in many pharmaceutical industries. Therefore, ...

    Authors: Poonam Kumari, Nikky Deepa, Prabodh Kumar Trivedi, Brajesh K. Singh, Vaibhav Srivastava and Akanksha Singh
    Citation: Microbial Cell Factories 2023 22:226

    The Correction to this article has been published in Microbial Cell Factories 2024 23:1

  37. Lacticaseibacillus is one of the predominant microorganisms in gut from human and animal, and the lacticaseibacillus have effective applications against the viral diarrhea of piglets in the farm. However, the fun...

    Authors: Shaojun Chen, Zida Nai, Ziliang Qin, Gang Li, Xinmiao He, Wentao Wang, Yaguang Tian, Di Liu and Xinpeng Jiang
    Citation: Microbial Cell Factories 2023 22:225
  38. Protein purification remains a critical need for biosciences and biotechnology. It frequently requires multiple rounds of chromatographic steps that are expensive and time-consuming. Our lab previously reporte...

    Authors: Guang Zeng, Yinzhen Zheng, Ya Xiang, Run Liu, Xiaofeng Yang and Zhanglin Lin
    Citation: Microbial Cell Factories 2023 22:224
  39. Lactic acid is one of the most important organic acids, with various applications in the food, beverage, pharmaceutical, cosmetic, and chemical industries. Optically pure forms of L- and D-lactic acid produced...

    Authors: Ernesta Augustiniene, Ilona Jonuskiene, Jurgita Kailiuviene, Edita Mazoniene, Kestutis Baltakys and Naglis Malys
    Citation: Microbial Cell Factories 2023 22:223

    The Correction to this article has been published in Microbial Cell Factories 2023 22:249

  40. Oxytetracycline which is derived from Streptomyces rimosus, inhibits a wide range of bacteria and is industrially important. The underlying biosynthetic processes are complex and hinder rational engineering, so i...

    Authors: Selma Beganovic, Christian Rückert-Reed, Hilda Sucipto, Wei Shu, Lars Gläser, Thomas Patschkowski, Ben Struck, Jörn Kalinowski, Andriy Luzhetskyy and Christoph Wittmann
    Citation: Microbial Cell Factories 2023 22:222
  41. Normally, a salt amount greater than 3.5% (w/v) is defined as hypersaline. Large amounts of hypersaline wastewater containing organic pollutants need to be treated before it can be discharged into the environm...

    Authors: Jie Zheng, Zhengzhi Zhang, Juan An, Yubin Xue and Bo Yu
    Citation: Microbial Cell Factories 2023 22:220
  42. Production of plant secondary metabolites in engineered microorganisms provides a scalable and sustainable alternative to their sourcing from nature or through chemical synthesis. However, the biosynthesis of ...

    Authors: Michal Poborsky, Christoph Crocoll, Mohammed Saddik Motawie and Barbara Ann Halkier
    Citation: Microbial Cell Factories 2023 22:219
  43. Identification and characterization of novel, faithful and processive DNA polymerases is a driving force in the development of DNA amplification methods. Purification of proteins from natural phages is often t...

    Authors: Pengjun Han, Huahao Fan and Yigang Tong
    Citation: Microbial Cell Factories 2023 22:217
  44. Lignocellulosic biomass plays a crucial role in creating a circular bioeconomy and minimizing environmental impact. Enset biomass is a byproduct of traditional Ethiopian Enset food processing that is thrown aw...

    Authors: Nebyat Seid, Katrin Ochsenreither and Anke Neumann
    Citation: Microbial Cell Factories 2023 22:216
  45. Seleno-methylselenocysteine (SeMCys) is an effective component of selenium supplementation with anti-carcinogenic potential that can ameliorate neuropathology and cognitive deficits. In a previous study, a SeM...

    Authors: Xian Yin, Meiyi Zhao, Yu Zhou, Hulin Yang, Yonghong Liao and Fenghuan Wang
    Citation: Microbial Cell Factories 2023 22:215

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