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  1. The global demand for plant oil has reached unprecedented levels and is relevant in all industrial sectors. Driven by the growing awareness for environmental issues of traditional plant oils and the need for e...

    Authors: Paul Richter, Jathurshan Panchalingam, Katharina Miebach, Kerstin Schipper, Michael Feldbrügge and Marcel Mann
    Citation: Microbial Cell Factories 2024 23:204
  2. Over the last two decades, hybridization has been a powerful tool used to construct superior yeast for brewing and winemaking. Novel hybrids were primarily constructed using at least one Saccharomyces cerevisiae ...

    Authors: Karolina Drężek, Zsuzsa Antunovics and Agnieszka Karolina Grabiec
    Citation: Microbial Cell Factories 2024 23:203
  3. Microbial genome sequencing and analysis revealed the presence of abundant silent secondary metabolites biosynthetic gene clusters (BGCs) in streptomycetes. Activating these BGCs has great significance for dis...

    Authors: Junyue Li, Kai Wang, Sainan Luo, Yuqing Tian, Yue Li, Songnian Hu, Huarong Tan, Jihui Zhang and Jine Li
    Citation: Microbial Cell Factories 2024 23:202
  4. Ethanol shock significantly affects expression of over 1200 genes in Streptomyces venezuelae NRRL B-65,442, including those involved in secondary metabolite biosynthesis and a cryptic gene pepX, which encodes a 1...

    Authors: Olga N. Sekurova, Martin Zehl, Michael Predl, Peter Hunyadi, Thomas Rattei and Sergey B. Zotchev
    Citation: Microbial Cell Factories 2024 23:201
  5. Hyaluronidase (hyase) is an endoglycosidase enzyme that degrades hyaluronic acid (HA) and is mostly known to be found in the extracellular matrix of connective tissues. In the current study, eleven bacteria is...

    Authors: Mai A. Ebraheem, Esmail M. El-Fakharany, Sherif Moussa Husseiny and Fafy A. Mohammed
    Citation: Microbial Cell Factories 2024 23:200
  6. The demand for bioplastics has increased exponentially as they have emerged as alternatives to petrochemical plastics. However, there is a substantial lack of knowledge regarding bioplastic degradation. This s...

    Authors: Darsha Prabhaharan, Hyojung Park, Okkyoung Choi, Amith Abraham and Byoung-In Sang
    Citation: Microbial Cell Factories 2024 23:199
  7. Komagataella phaffii, a type of methanotrophic yeast, can use methanol, a favorable non-sugar substrate in eco-friendly bio-manufacturing. The dissimilation pathway in K. phaffii leads to the loss of carbon atoms...

    Authors: Yuanyuan Wang, Ruisi Li, Fengguang Zhao, Shuai Wang, Yaping Zhang, Dexun Fan and Shuangyan Han
    Citation: Microbial Cell Factories 2024 23:198
  8. Telomerase activators are promising agents for the healthy aging process and the treatment/prevention of short telomere-related and age-related diseases. The discovery of new telomerase activators and later op...

    Authors: Melis Küçüksolak, Hasan Buğra Çoban and Erdal Bedir
    Citation: Microbial Cell Factories 2024 23:196
  9. This study explores a sustainable approach for synthesizing silver nanocomposites (AgNCs) with enhanced antimicrobial and bioactivity using safe Lactobacillus strains and a whey-based medium (WBM). WBM effectivel...

    Authors: E. B. El.Fadly, A. S. Salah, B. Abdella, A. Al Ali, H. AlShmrany, A. M. ElBaz, N. S. Abdelatty, E. F. Khamis, O. F. Maagouz, M. A. Salamah, M. N. Saleh, H. K. Sakr and M. A. El-Kemary
    Citation: Microbial Cell Factories 2024 23:195
  10. Biotransformation of CO2 into high-value-added carbon-based products is a promising process for reducing greenhouse gas emissions. To realize the green transformation of CO2, we use fatty acids as carbon source t...

    Authors: Linqing Li, Xiuyuan Zhou, Zhuoao Gao, Peng Xiong and Xiutao Liu
    Citation: Microbial Cell Factories 2024 23:194
  11. Due to the complexity of the metabolic pathway network of active ingredients, precise targeted synthesis of any active ingredient on a synthetic network is a huge challenge. Based on a complete analysis of the...

    Authors: Yuqi Qiao, Doudou Huang, Yajing Li, Songfan Jiang, Xiao Chen, Junfeng Chen, Ying Xiao and Wansheng Chen
    Citation: Microbial Cell Factories 2024 23:193
  12. In this study, we isolated a cellulase-producing bacterium, Bacillus amyloliquefaciens strain elh, from rice peel. We employed two optimization methods to enhance the yield of cellulase. Firstly, we utilized a on...

    Authors: Elham F. El-Khamisi, Effat A. M. Soliman, Ghada M. El-Sayed, Shaimaa A. Nour, Mohamed O. Abdel-Monem and Mervat G. Hassan
    Citation: Microbial Cell Factories 2024 23:191
  13. Carbonic anhydrase (CA) enzymes facilitate the reversible hydration of CO2 to bicarbonate ions and protons. Identifying efficient and robust CAs and expressing them in model host cells, such as Escherichia coli, ...

    Authors: Hui Wei, Vladimir V. Lunin, Markus Alahuhta, Michael E. Himmel, Shu Huang, Yannick J. Bomble and Min Zhang
    Citation: Microbial Cell Factories 2024 23:190
  14. Developing special textiles (for patients in hospitals for example) properties, special antimicrobial and anticancer, was the main objective of the current work. The developed textiles were produced after dyei...

    Authors: Osama M. Darwesh, Ahmed Marzoog, Ibrahim A. Matter, Mohammad K. Okla, Mohamed A. El-Tayeb, Mohammed Aufy, Turki M. Dawoud and Mostafa A. Abdel-Maksoud
    Citation: Microbial Cell Factories 2024 23:189
  15. Advancing the engineering of photosynthesis-based prokaryotic cell factories is important for sustainable chemical production and requires a deep understanding of the interplay between bioenergetic and metabol...

    Authors: Dorota Muth-Pawlak, Lauri Kakko, Pauli Kallio and Eva-Mari Aro
    Citation: Microbial Cell Factories 2024 23:188
  16. Plastic is widely utilized in packaging, frameworks, and as coverings material. Its overconsumption and slow degradation, pose threats to ecosystems due to its toxic effects. While polyhydroxyalkanoates (PHA) ...

    Authors: Vishal Ahuja, Pankaj Kumar Singh, Chandan Mahata, Jong-Min Jeon, Gopalakrishnan Kumar, Yung-Hun Yang and Shashi Kant Bhatia
    Citation: Microbial Cell Factories 2024 23:187
  17. Oritavancin is a new generation of semi-synthetic glycopeptide antibiotics against Gram-positive bacteria, which served as the first and only antibiotic with a single-dose therapeutic regimen to treat ABSSSI. ...

    Authors: Xinyi Zhao, Chenyang Zhu, Wenli Gao, Huang Xie, Zhongyuan Lyu, Qingwei Zhao and Yongquan Li
    Citation: Microbial Cell Factories 2024 23:186
  18. Currently, industrial fermentation of Botrytis cinerea is a significant source of abscisic acid (ABA). The crucial role of ABA in plants and its wide range of applications in agricultural production have resulted...

    Authors: Yifan Wang, Dan Shu, Zhemin Li, Di Luo, Jie Yang, Dongbo Chen, Tianfu Li, Xiaonan Hou, Qi Yang and Hong Tan
    Citation: Microbial Cell Factories 2024 23:185
  19. Chelerythrine is an important alkaloid used in agriculture and medicine. However, its structural complexity and low abundance in nature hampers either bulk chemical synthesis or extraction from plants. Here, w...

    Authors: Jiawei Zhu, Kai Zhang, Yuanzhi He, Qi Zhang, Yanpeng Ran, Zaigao Tan, Li Cui and Yan Feng
    Citation: Microbial Cell Factories 2024 23:183
  20. Guanosine is a purine nucleoside that is widely used as a raw material for food additives and pharmaceutical products. Microbial fermentation is the main production method of guanosine. However, the guanosine-...

    Authors: Kun Zhang, Mengxing Qin, Yu Hou, Wenwen Zhang, Zhenyu Wang and Hailei Wang
    Citation: Microbial Cell Factories 2024 23:182
  21. Volatile compounds are key elements in the interaction and communication between organisms at both interspecific and intraspecific levels. In complex bacterial communities, the emission of these fast-acting ch...

    Authors: Lorena Cuervo, Carmen Méndez, José A. Salas, Carlos Olano and Mónica G. Malmierca
    Citation: Microbial Cell Factories 2024 23:181
  22. Nowadays, biofuels, especially bioethanol, are becoming increasingly popular as an alternative to fossil fuels. Zymomonas mobilis is a desirable species for bioethanol production due to its unique characteristics...

    Authors: Shaqayeq Asefi, Hoda Nouri, Golchehr Pourmohammadi and Hamid Moghimi
    Citation: Microbial Cell Factories 2024 23:180
  23. Human lysozyme (hLYZ) is a natural antibacterial protein with broad applications in food and pharmaceutical industries. Recombinant production of hLYZ in Komagataella phaffii (K. phaffii) has attracted considerab...

    Authors: Yong-Jun Zhong, Yang-Yang Luo, Haiyang Xia, Qing-Wei Zhao and Xu-Ming Mao
    Citation: Microbial Cell Factories 2024 23:179
  24. Computational mining of useful enzymes and biosynthesis pathways is a powerful strategy for metabolic engineering. Through systematic exploration of all conceivable combinations of enzyme reactions, including ...

    Authors: Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J. Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo and Tomohisa Hasunuma
    Citation: Microbial Cell Factories 2024 23:178
  25. Heme-incorporating peroxygenases are responsible for electron transport in a multitude of organisms. Yet their application in biocatalysis is hindered due to their challenging recombinant production. Previous ...

    Authors: Mihail Besleaga, Christian Zimmermann, Katharina Ebner, Robert L. Mach, Astrid R. Mach-Aigner, Martina Geier, Anton Glieder, Oliver Spadiut and Julian Kopp
    Citation: Microbial Cell Factories 2024 23:177
  26. Bacterial infections and the rising antimicrobial resistance pose a significant threat to public health. Pseudomonas aeruginosa produces bacteriocins like pyocins, especially S-type pyocins, which are promising f...

    Authors: Hamed Charkhian, Ehsan Soleimannezhadbari, Amin Bodaqlouei, Lida Lotfollahi, Hajie Lotfi, Nesa Yousefi, Ehsan Shojadel and Zafar Gholinejad
    Citation: Microbial Cell Factories 2024 23:175
  27. The objectives of the current study were to extract pyocyanin from Pseudomonas aeruginosa clinical isolates, characterize its chemical nature, and assess its biological activity against different bacteria and can...

    Authors: Moustafa A. Marey, Rania Abozahra, Nefertiti A. El-Nikhely, Miranda F. Kamal, Sarah M. Abdelhamid and Mohammed A. El-Kholy
    Citation: Microbial Cell Factories 2024 23:174
  28. There is increasing evidence that probiotic and commensal bacteria play a role in substrate metabolism, energy harvesting and intestinal homeostasis, and may exert immunomodulatory activities on human health. ...

    Authors: Luis G. Bermúdez-Humarán, Benoit Chassaing and Philippe Langella
    Citation: Microbial Cell Factories 2024 23:172
  29. Fibroblast growth factor 21 (FGF21) is a promising candidate for treating metabolic disorder diseases and has been used in phase II clinical trials. Currently, metabolic diseases are prevalent worldwide, under...

    Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang and Xianlong Ye
    Citation: Microbial Cell Factories 2024 23:171
  30. The gram-positive bacterium Bacillus subtilis is widely used for industrial enzyme production. Its ability to secrete a wide range of enzymes into the extracellular medium especially facilitates downstream proces...

    Authors: Jana Senger, Ines Seitl, Eva Pross and Lutz Fischer
    Citation: Microbial Cell Factories 2024 23:170
  31. In vitro expression involves the utilization of the cellular transcription and translation machinery in an acellular context to produce one or more proteins of interest and has found widespread application in ...

    Authors: Ana L. J. L. Ribeiro, Patricia Pérez-Arnaiz, Mercedes Sánchez-Costa, Lara Pérez, Marcos Almendros, Liisa van Vliet, Fabrice Gielen, Jesmine Lim, Simon Charnock, Florian Hollfelder, J. Eduardo González-Pastor, José Berenguer and Aurelio Hidalgo
    Citation: Microbial Cell Factories 2024 23:169
  32. Microbially induced calcium carbonate precipitation has been extensively researched for geoengineering applications as well as diverse uses within the built environment. Bacteria play a crucial role in produci...

    Authors: Katie A. Gilmour, Prakriti Sharma Ghimire, Jennifer Wright, Jamie Haystead, Martyn Dade-Robertson, Meng Zhang and Paul James
    Citation: Microbial Cell Factories 2024 23:168
  33. White-rot fungi are known to naturally produce high quantities of laccase, which exhibit commendable stability and catalytic efficiency. However, their laccase production does not meet the demands for industri...

    Authors: Long-Bin Zhang, Xiu-Gen Qiu, Ting-Ting Qiu, Zhou Cui, Yan Zheng and Chun Meng
    Citation: Microbial Cell Factories 2024 23:167

    The Correction to this article has been published in Microbial Cell Factories 2024 23:197

  34. Recombinant peptide production in Escherichia coli provides a sustainable alternative to environmentally harmful and size-limited chemical synthesis. However, in-vivo production of disulfide-bonded peptides at hi...

    Authors: Martin Gibisch, Matthias Müller, Christopher Tauer, Bernd Albrecht, Rainer Hahn, Monika Cserjan-Puschmann and Gerald Striedner
    Citation: Microbial Cell Factories 2024 23:166
  35. The increased use of biofuels in place of fossil fuels is one strategy to support the transition to net-zero carbon emissions, particularly in transport applications. However, expansion of the use of 1st gener...

    Authors: Joseph Calverley, Christopher Ibenegbu, Abdulkadir Hussein-Sheik, H. C. Hemaka Bandulasena and David J. Leak
    Citation: Microbial Cell Factories 2024 23:165
  36. Optically active D-amino acids are widely used as intermediates in the synthesis of antibiotics, insecticides, and peptide hormones. Currently, the two-enzyme cascade reaction is the most efficient way to prod...

    Authors: Fa Zhang, Muhammad Naeem, Bo Yu, Feixia Liu and Jiansong Ju
    Citation: Microbial Cell Factories 2024 23:164

    The Correction to this article has been published in Microbial Cell Factories 2024 23:192

  37. Type I interferons (IFN-I)—a group of cytokines with immunomodulatory, antiproliferative, and antiviral properties—are widely used as therapeutics for various cancers and viral diseases. Since IFNs are protein...

    Authors: Irina Rostovsky, Uri Wieler, Alona Kuzmina, Ran Taube and Neta Sal-Man
    Citation: Microbial Cell Factories 2024 23:163
  38. Wastewater treatment plants contribute approximately 6% of anthropogenic methane emissions. Methanotrophs, capable of converting methane into polyhydroxybutyrate (PHB), offer a promising solution for utilizing...

    Authors: Hyerim Eam, Dayoung Ko, Changsoo Lee and Jaewook Myung
    Citation: Microbial Cell Factories 2024 23:160
  39. Bacillus subtilis is widely used in industrial-scale riboflavin production. Previous studies have shown that targeted mutagenesis of the ribulose 5-phosphate 3-epimerase in B. subtilis can significantly enhance r...

    Authors: Chuan Liu, Miaomiao Xia, Huan Fang, Fan Xu, Sijia Wang and Dawei Zhang
    Citation: Microbial Cell Factories 2024 23:159
  40. This study explores the biosynthesis, characteristics, and functional properties of exopolysaccharide produced by the strain Liquorilactobacillus mali T6-52. The strain demonstrated significant EPS production wit...

    Authors: Manyu Wu, Shadi Pakroo, Chiara Nadai, Zeno Molinelli, Immacolata Speciale, Crisitina De Castro, Armin Tarrah, Jijin Yang, Alessio Giacomini and Viviana Corich
    Citation: Microbial Cell Factories 2024 23:158
  41. This study aimed to investigate the operation of three parallel biotrickling filters (BTFs) in removing H2S at different pH conditions (haloalkaliphilic, neutrophilic, and acidophilic) and their associated microb...

    Authors: Abbas Abbas Rouhollahi, Minoo Giyahchi, Seyed Mohammad Mehdi Dastgheib and Hamid Moghimi
    Citation: Microbial Cell Factories 2024 23:157
  42. Biosynthesis of metallic nanoparticles using microorganisms are a fabulous and emerging eco-friendly science with well-defined sizes, shapes and controlled monodispersity. Copper nanoparticles, among other met...

    Authors: Nahla M. Abdel Aziz, Doaa A. Goda, Dina I. Abdel-Meguid, Ebaa E. EL-Sharouny and Nadia A. Soliman
    Citation: Microbial Cell Factories 2024 23:156
  43. Rhizomucor miehei (RM) lipase is a regioselective lipase widely used in food, pharmaceutical and biofuel industries. However, the high cost and low purity of the commercial RM lipase limit its industrial applicat...

    Authors: Mingjun Yang, Xianhui Su, Jun Yang, Zhiwen Lu, Jie Zhou, Fei Wang, Yang Liu, Lixin Ma and Chao Zhai
    Citation: Microbial Cell Factories 2024 23:155

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