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  1. Bioemulsifiers are natural or microbial-based products with the ability to emulsify hydrophobic compounds in water. These compounds are biodegradable, eco-friendly, and find applications in various industries.

    Authors: Yasmina A. Elsaygh, Mona K. Gouda, Yasser Elbahloul, Moustafa Abdel Hakim and Nancy M. El Halfawy
    Citation: Microbial Cell Factories 2023 22:176
  2. Surface display co-opts yeast’s innate ability to embellish its cell wall with mannoproteins, thus converting the yeast’s outer surface into a growing and self-sustaining catalyst. However, the efficient toolb...

    Authors: Tea Martinić Cezar, Mateja Lozančić, Ana Novačić, Ana Matičević, Dominik Matijević, Béatrice Vallée, Vladimir Mrša, Renata Teparić and Bojan Žunar
    Citation: Microbial Cell Factories 2023 22:174
  3. Marine macroalgae have gained interest recently, mostly due to their bioactive components. Polycladia crinita is an example of marine macroalgae from the Phaeophyceae class, also known as brown algae. They are ch...

    Authors: Alanood S. Almurshedi, Thanaa A. El-Masry, Hend Selim, Mostafa M. El-Sheekh, Mofida E. M. Makhlof, Basmah N. Aldosari, Iman M. Alfagih, Bushra T. AlQuadeib, Salma S. Almarshidy and Maisra M. El-Bouseary
    Citation: Microbial Cell Factories 2023 22:173
  4. Pyruvate is a widely used value-added chemical which also serves as a hub of various metabolic pathways. The fastest-growing bacterium Vibrio natriegens is a promising chassis for synthetic biology applications w...

    Authors: Fengli Wu, Shucai Wang, Yanfeng Peng, Yufeng Guo and Qinhong Wang
    Citation: Microbial Cell Factories 2023 22:172
  5. Polyhydroxyalkanoate (PHA) is one of the most promising materials for replacing petroleum-based plastics, and it can be produced from various renewable biomass sources. In this study, PHA production was conduc...

    Authors: Yerin Park, Jong-Min Jeon, Jea-Kyung Park, Yung-Hun Yang, Shin Sik Choi and Jeong-Jun Yoon
    Citation: Microbial Cell Factories 2023 22:171
  6. Oro-gastrointestinal stress in the digestive tract is the main stress to which orally administered probiotics are exposed. The regulation of oro-gastrointestinal transit (OGT) stress on the adhesion and surviv...

    Authors: Dawei Chen, Chunmeng Chen, Congcong Guo, Hui Zhang, Yating Liang, Yue Cheng, Hengxian Qu, Yunchao Wa, Chenchen Zhang, Chengran Guan, Jianya Qian and Ruixia Gu
    Citation: Microbial Cell Factories 2023 22:170
  7. Endophytes, especially those isolated from herbal plants, may act as a reservoir of a variety of secondary metabolites exhibiting biological activity. Some endophytes express the ability to produce the same bi...

    Authors: Olga Marchut-Mikołajczyk, Magdalena Chlebicz, Monika Kawecka, Agnieszka Michalak, Filip Prucnal, Maciej Nielipinski, Jakub Filipek, Michalina Jankowska, Zofia Perek, Piotr Drożdżyński, Natalia Rutkowska and Anna Otlewska
    Citation: Microbial Cell Factories 2023 22:169
  8. Microbial production of aromatic chemicals is an attractive method for obtaining high-performance materials from biomass resources. A non-proteinogenic amino acid, 4-amino-3-hydroxybenzoic acid (4,3-AHBA), is ...

    Authors: Kyoshiro Nonaka, Tatsuya Osamura and Fumikazu Takahashi
    Citation: Microbial Cell Factories 2023 22:168
  9. Pyocyanin is a secondary metabolite secreted by P. aeruginosa. It is a redox-active blue/green phenazine pigment that has various beneficial applications. The present study aims at screening the production of pyo...

    Authors: Heba Shouman, Heba Shehta Said, Hany I. Kenawy and Ramadan Hassan
    Citation: Microbial Cell Factories 2023 22:166
  10. 3-Hydroxybutanone (Acetoin, AC) and 2,3-butanediol (BD) are two essential four-carbon platform compounds with numerous pharmaceutical and chemical synthesis applications. AC and BD have two and three stereoiso...

    Authors: Yuchen Li, Xiangying Zhao, Mingjing Yao, Wenli Yang, Yanlei Han, Liping Liu, Jiaxiang Zhang and Jianjun Liu
    Citation: Microbial Cell Factories 2023 22:165
  11. Recently, researchers have focused on the search for alternatives to conventional antibiotics. Antimicrobial peptides are small bioactive peptides that regulate immune activation and have antibacterial activit...

    Authors: Chunming Dong, Lijun Xu, Weitao Lu, Mengru Li, Rui Zhang, Yanyan Sun, Jian Liu and Xinlei Chu
    Citation: Microbial Cell Factories 2023 22:164
  12. Poly-β-hydroxybutyrate (PHB), produced by a variety of microbial organisms, is a good substitute for petrochemically derived plastics due to its excellent properties such as biocompatibility and biodegradabili...

    Authors: Yue Ming, Guoqiang Li, Zhuangzhuang Shi, Xin Zhao, Yufei Zhao, Ge Gao, Ting Ma and Mengmeng Wu
    Citation: Microbial Cell Factories 2023 22:162
  13. The non-conventional yeast Rhodotorula toruloides is an emerging host organism in biotechnology by merit of its natural capacity to accumulate high levels of carotenoids and intracellular storage lipids from a va...

    Authors: Daniel P. Brink, Friederike Mierke, Joakim Norbeck, Verena Siewers and Thomas Andlid
    Citation: Microbial Cell Factories 2023 22:160
  14. Conjugate vaccines produced either by chemical or biologically conjugation have been demonstrated to be safe and efficacious in protection against several deadly bacterial diseases. However, conjugate vaccine ...

    Authors: Sherif Abouelhadid, Elizabeth R. Atkins, Emily J. Kay, Ian J. Passmore, Simon J. North, Burhan Lehri, Paul Hitchen, Eirik Bakke, Mohammed Rahman, Janine T. Bossé, Yanwen Li, Vanessa S. Terra, Paul R. Langford, Anne Dell, Brendan W. Wren and Jon Cuccui
    Citation: Microbial Cell Factories 2023 22:159
  15. During the production of L-arginine through high dissolved oxygen and nitrogen supply fermentation, the industrial workhorse Corynebacterium glutamicum is exposed to oxidative stress. This generates reactive oxyg...

    Authors: Ziqin Jiang, Jingyi Guan, Tingting Liu, Chunyu Shangguan, Meijuan Xu and Zhiming Rao
    Citation: Microbial Cell Factories 2023 22:158
  16. New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic chemical pesticides and to combat growing levels of pest...

    Authors: Jake S. De-Thier, Prashant Pyati, Jack Bell, Jennifer J. Readshaw, Adrian P. Brown and Elaine C. Fitches
    Citation: Microbial Cell Factories 2023 22:157
  17. Sm1 and Chit42 of Trichoderma have been universally confirmed as crucial biocontrol factors against pathogen infection through induced resistance and mycoparasitism, respectively. However, not enough work has bee...

    Authors: Hongyi Liu, Shaoqing Wang, Bo Lang, Yaqian Li, Xinhua Wang and Jie Chen
    Citation: Microbial Cell Factories 2023 22:156
  18. Yarrowia lipolytica is a dimorphic fungus, which switches from yeast to filament form in response to environmental conditions. For industrial purposes it is important to lock cells in the yeast or filamentous for...

    Authors: Dorota A. Rzechonek, Mateusz Szczepańczyk and Aleksandra M. Mirończuk
    Citation: Microbial Cell Factories 2023 22:155
  19. Using fungal biomass for biocatalysis is a potential solution for the expensive cost of the use o enzymes. Production of fungal biomass with effective activity requires optimizing the cultivation conditions.

    Authors: Nadeem I. Elhussieny, Heba A. El-Refai, Sayeda S. Mohamed, Yousseria M. Shetaia, Hala A. Amin and Gerd Klöck
    Citation: Microbial Cell Factories 2023 22:154
  20. The omnipresence of population heterogeneity in industrial bioprocesses originates from prevailing dynamic bioprocess conditions, which promote differences in the expression of cellular characteristics. Despit...

    Authors: Manh Dat Hoang, Ingmar Polte, Lukas Frantzmann, Nikolas von den Eichen, Anna-Lena Heins and Dirk Weuster-Botz
    Citation: Microbial Cell Factories 2023 22:153
  21. Despite being necessary, copper is a toxic heavy metal that, at high concentrations, harms the life system. The parameters that affect the bioreduction and biosorption of copper are highly copper-resistant bac...

    Authors: Amal William Danial and Fatma Mohamed Dardir
    Citation: Microbial Cell Factories 2023 22:152
  22. Methionine is an essential amino acid in mammals and a precursor for vital metabolites required for the survival of all organisms. Consequently, its inclusion is required in diverse applications, such as food,...

    Authors: Nadya Gruzdev, Yael Hacham, Hadar Haviv, Inbar Stern, Matan Gabay, Itai Bloch, Rachel Amir, Maayan Gal and Itamar Yadid
    Citation: Microbial Cell Factories 2023 22:151
  23. Glucoamylase is an important enzyme for starch saccharification in the food and biofuel industries and mainly produced from mesophilic fungi such as Aspergillus and Rhizopus species. Enzymes produced from thermop...

    Authors: Zhijian Zhu, Manyu Zhang, Dandan Liu, Defei Liu, Tao Sun, Yujing Yang, Jiacheng Dong, Huanhuan Zhai, Wenliang Sun, Qian Liu and Chaoguang Tian
    Citation: Microbial Cell Factories 2023 22:150
  24. Lanthipeptides are a rapidly expanding family of ribosomally synthesized and post-translationally modified natural compounds with diverse biological functions. Lanthipeptide structural and biosynthetic genes c...

    Authors: Winschau F Van Zyl, Anton D. Van Staden, Leon M T. Dicks and Marla Trindade
    Citation: Microbial Cell Factories 2023 22:149
  25. Colorectal cancer (CRC) is the third cause of death by cancers worldwide and is one of the most common cancer types reported in both Egypt and the United States. The use of probiotics as a dietary therapy is i...

    Authors: Gaber A. Abo-Zaid, Ahmed M. Kenawy, Nehal M. El-Deeb and Lamiaa A. Al-Madboly
    Citation: Microbial Cell Factories 2023 22:148
  26. Vanillin (4-hydroxy-3-methoxybenzaldehyde) is one of the most popular flavors with wide applications in food, fragrance, and pharmaceutical industries. However, the high cost and limited yield of plant extract...

    Authors: Ying Liu, Lichao Sun, Yi-Xin Huo and Shuyuan Guo
    Citation: Microbial Cell Factories 2023 22:147
  27. Authors: Beata Łubkowska, Edyta Czajkowska, Aleksandra Stodolna, Michał Sroczyński, Agnieszka Zylicz-Stachula, Ireneusz Sobolewski and Piotr M. Skowron
    Citation: Microbial Cell Factories 2023 22:146

    The original article was published in Microbial Cell Factories 2023 22:80

  28. R. toruloides is an oleaginous yeast, with diverse metabolic capacities and high tolerance for inhibitory compounds abundant in plant biomass hydrolysates. While R. toruloides grows on several pentose sugars and ...

    Authors: Paul A. Adamczyk, Samuel T. Coradetti and John M. Gladden
    Citation: Microbial Cell Factories 2023 22:145
  29. Efficient conversion of pentose sugars remains a significant barrier to the replacement of petroleum-derived chemicals with plant biomass-derived bioproducts. While the oleaginous yeast Rhodosporidium toruloides ...

    Authors: Samuel T. Coradetti, Paul A. Adamczyk, Di Liu, Yuqian Gao, Peter B. Otoupal, Gina M. Geiselman, Bobbie-Jo M. Webb-Robertson, Meagan C. Burnet, Young-Mo Kim, Kristin E. Burnum-Johnson, Jon Magnuson and John M. Gladden
    Citation: Microbial Cell Factories 2023 22:144
  30. Fungal producing potency of camptothecin (CPT) raise the hope for their usage to be a platform for industrial production of CPT, nevertheless, attenuation of their productivity of CPT with the subculturing and...

    Authors: Abeer Eldeghidy, Gamal Abdel-Fattah, Ashraf S. A. El-Sayed and Ghada G. Abdel-Fattah
    Citation: Microbial Cell Factories 2023 22:143
  31. Malachite Green (MG) dye of the triphenylmethane group is a toxic compound used in the aquaculture industry as an antifungal agent, however, it can accumulate in fish and pose toxicity. The present work aims t...

    Authors: Abanaoub Efraim, Mai Saeed, Mariam Ahmed Elbaz, Mohamed Alaa, Noran Ahmed, Rana Adel, Yara Hazem, Einas Elshatoury and Ola M. Gomaa
    Citation: Microbial Cell Factories 2023 22:142
  32. The purpose of the current study is to isolate a heavily amylase-producing bacteria of the genus Bacillus from soil samples, optimize the production of the enzyme, purify it, and evaluate its activity against bio...

    Authors: Amal M. Abo-Kamer, Ibrahim S. Abd-El-salam, Faten A. Mostafa, Abd-El-Rahman A. Mustafa and Lamiaa A. Al-Madboly
    Citation: Microbial Cell Factories 2023 22:141
  33. A sustainable biorefining and bioprocessing strategy was developed to produce edible-ulvan films and non-edible polyhydroxybutyrate films. The preparation of edible-ulvan films by crosslinking and plasticisati...

    Authors: N. Arul Manikandan and Piet N. L. Lens
    Citation: Microbial Cell Factories 2023 22:140
  34. Triterpenoids have shown a wide range of biological activities including antitumor and antiviral effects. Typically, triterpenes are synthesized through the mevalonate pathway and are extracted from natural pl...

    Authors: Xinwei Wang, Haibo Wu, Ka Hong Wong, Yixuan Wang, Baixiong Chen and Kun Feng
    Citation: Microbial Cell Factories 2023 22:139
  35. l-arginine is an important amino acid with applications in diverse industrial and pharmaceutical fields. n-acetylglutamate, synthesized from l-glutamate and acetyl-CoA, is a precursor of the l-arginine biosynthet...

    Authors: Mengzhen Nie, Jingyu Wang and Kechun Zhang
    Citation: Microbial Cell Factories 2023 22:138

    The Correction to this article has been published in Microbial Cell Factories 2024 23:47

  36. As a concentrated energy source with high added value, hydrogen has great development prospects, with special emphasis on sustainable microbial production as a replacement for traditional fossil fuels. In this...

    Authors: Ke Jiang, Ruoxuan Bai, Ting Gao, Ping Lu, Jingya Zhang, Shuting Zhang, Fangxu Xu, Shenghou Wang and Hongxin Zhao
    Citation: Microbial Cell Factories 2023 22:137
  37. Beet filter cake (BFC) is a by-product of sugar beet processing, which is difficult to dispose of and involves severe environmental concerns. Spirulina platensis is a microalga with a high protein content essenti...

    Authors: Sara Saad, Mervat Hosny Hussien, Ghada Samir Abou-ElWafa, Heshmat Soliman Aldesuquy and Eladl Eltanahy
    Citation: Microbial Cell Factories 2023 22:136
  38. Ablynx NV, a subsidiary of Sanofi, has a long-standing focus on the development of Nanobody® molecules as biopharmaceuticals (Nanobody® is a registered trademark of Ablynx NV). Nanobody molecules are single va...

    Authors: Manu De Groeve, Bram Laukens and Peter Schotte
    Citation: Microbial Cell Factories 2023 22:135
  39. Hydrogenases (H2ases) are metalloenzymes capable of the reversible conversion of protons and electrons to molecular hydrogen. Exploiting the unique enzymatic activity of H2ases can lead to advancements in the ...

    Authors: Malgorzata Witkowska, Robert P. Jedrzejczak, Andrzej Joachimiak, Onur Cavdar, Anna Malankowska, Piotr M. Skowron and Agnieszka Zylicz-Stachula
    Citation: Microbial Cell Factories 2023 22:134
  40. The global market of plant-based milk alternatives is continually growing. Flavour and taste have a key impact on consumers’ selection of plant-based beverages. Unfortunately, natural plant milks have only lim...

    Authors: Muzi Tangyu, Michel Fritz, Jan Patrick Tan, Lijuan Ye, Christoph J. Bolten, Biljana Bogicevic and Christoph Wittmann
    Citation: Microbial Cell Factories 2023 22:133
  41. Actinomycetes Streptomyces davaonensis and Streptomyces cinnabarinus synthesize a promising broad-spectrum antibiotic roseoflavin, with its synthesis starting from flavin mononucleotide and proceeding through an ...

    Authors: Kostyantyn V. Dmytruk, Justyna Ruchala, Liubov R. Fayura, Grzegorz Chrzanowski, Olena V. Dmytruk, Andriy O. Tsyrulnyk, Yuliia A. Andreieva, Daria V. Fedorovych, Olena I. Motyka, Diethard Mattanovich, Hans Marx and Andriy A. Sibirny
    Citation: Microbial Cell Factories 2023 22:132
  42. Escherichia coli is a useful platform for producing valuable materials through the implementation of synthetic gene(s) derived from other organisms. The production of lactate (LA)-based polyester poly[LA-co-3-hyd...

    Authors: Yuki Nagao, Sangho Koh, Seiichi Taguchi and Tomohiro Shimada
    Citation: Microbial Cell Factories 2023 22:131
  43. Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, includ...

    Authors: Laura M. Helleckes, Debora Puchta, Hannah Czech, Holger Morschett, Bertram Geinitz, Wolfgang Wiechert and Marco Oldiges
    Citation: Microbial Cell Factories 2023 22:130
  44. Polyhydroxybutyrate (PHB) is currently the most common polymer produced by natural bacteria and alternative to conventional petrochemical-based plastics due to its similar material properties and biodegradabil...

    Authors: Nan Jiang, Ming Wang, Linxin Song, Dengbin Yu, Shuangzi Zhou, Yu Li, Haiyan Li and Xuerong Han
    Citation: Microbial Cell Factories 2023 22:129
  45. Mitochondrial carriers (MCs) can deeply affect the intracellular flux distribution of metabolic pathways. The manipulation of their expression level, to redirect the flux toward the production of a molecule of...

    Authors: Eugenia Messina, Camilla Pires de Souza, Claudia Cappella, Simona Nicole Barile, Pasquale Scarcia, Isabella Pisano, Luigi Palmieri, Jean-Marc Nicaud and Gennaro Agrimi
    Citation: Microbial Cell Factories 2023 22:128
  46. Streptomyces are well known for their potential to produce various pharmaceutically active compounds, the commercial development of which is often limited by the low productivity and purity of the desired compoun...

    Authors: Wenli Guo, Zhihong Xiao, Tingting Huang, Kai Zhang, Hai-Xue Pan, Gong-Li Tang, Zixin Deng, Rubing Liang and Shuangjun Lin
    Citation: Microbial Cell Factories 2023 22:127
  47. Biosurfactants are surface-active compounds with environmental and industrial applications. These molecules show higher biocompatibility, stability and efficiency compared to synthetic surfactants. On the othe...

    Authors: Marco Andreolli, Valeria Villanova, Serena Zanzoni, Mariapina D’Onofrio, Giovanni Vallini, Nicola Secchi and Silvia Lampis
    Citation: Microbial Cell Factories 2023 22:126

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