Table 1 Metabolic engineering application in filamentous bacteria
From: Microbial cell factories based on filamentous bacteria, yeasts, and fungi
Category | Strategies | Strains | Products | Yield (g/g) | Titer (g/L) | Productivity (g/L/h) | Refs. |
|---|---|---|---|---|---|---|---|
Filamentous bacteria | Engineered bacteria | E. coli ftsZ (1 + 2 + 3 + 5) | PHB | – | 6.39 | – | [17] |
E. coli BL21 (DE3) (pet28asulA, p15apCAB) | P(3HB) | – | 2.27 | – | [18] | ||
Halomonas TD08 | PHB |  | 82.04% wt | – | [19] | ||
C. glutamicum AP4 | 5-aminolevulinic acid | – | 2.53 | 0.07 | [20] | ||
E. coli ftsW1 + ftsW4 | PHB | – | 93% wt | – | [21] | ||
Natural Actinomycetes | E. coli PLH4 | PLH |  | 52% wt | – | [22] | |
S. spinosa | Spinosad | – | 0.075 | – | [33] | ||
S. coelicolor | Pristinamycin II | – | 2.2 | 0.018 | [25] | ||
S. hygroscopicus-Δk-DR | Rapamycin | – | 0.25 | 0.002 | [139] | ||
S. pristinaespiralis ∆papR5 + R4R6/BAC-F1F15 | Pristinamycin II | – | 1.16 | 0.009 | [36] | ||
Streptomyces sp. RM7011 | FK506 | – | 0.16 | – | [23] | ||
S. venezuelae | Tylactone |  | 0.006 | – | [37] | ||
S. coelicolor | Rapamycin | – | 1.83 | 0.007 | [7] |