Table 1 Effect of various cellulase concentrations and overnight incubation with shaking on capsule stability
Incubation time | Observation | Cellulase concentration | |||||
|---|---|---|---|---|---|---|---|
10 U/mL | 1 U/mL | 0.5 U/mL | 0.1 U/mL | 0.05 U/mL | 0.01 U/mL | ||
1 h | Debris | + | − | − | − | − | − |
Burst on touch | + | − | − | − | − | − | |
2 h | Debris | + | + | − | − | − | − |
Burst on touch | + | − | − | − | − | − | |
3 h | Debris | ++ | + | − | − | − | − |
Burst on touch | + | + | − | − | − | − | |
8 h | Debris | +++ | + | − | − | − | − |
Burst on touch | + | + | + | + | + | − | |
Overnight | Debris | ++++ | + | − | − | − | − |
Burst on touch | + | + | + | + | + | + | |