Fig. 2

Growth and physiological profiles of duplicate A. niger cultures (strain DS3.1) during wave-mixed fed-batch cultivations. a Biomass titers produced by DS3.1 with talcum addition (closed symbols, replicates are represented by closed triangles and closed squares) and without talcum addition (open symbols, replicates are represented by open triangles and open squares). b Glucose concentrations in cultivations with (closed symbols) and without (open symbols) talcum. c Lactate concentrations in cultivations with (closed symbols) and without (open symbols) talcum. d Pyruvate concentrations in cultivations with (closed symbols) and without (open symbols) talcum. Start of glucose-feed and time of induction of Tet-on driven esyn expression via doxyxycline addition is indicated with a dashed line