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Figure 1 | Microbial Cell Factories

Figure 1

From: Production of cinnamic and p-hydroxycinnamic acid from sugar mixtures with engineered Escherichia coli

Figure 1

Central metabolism, sugar import routes and aromatics biosynthetic pathways. Dashed arrows indicate multiple enzyme reactions. EI, enzyme I; HPr, phosphohistidine carrier protein; EIIA, glucose-specific enzyme II; IICBGlc, integral membrane glucose permease; GalP, galactose permease; XylFGH, xylose transport proteins, AraFGH, arabinose transport proteins; G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; G3P, glyceraldehyde-3-phosphate; PEP, phosphoenolpyruvate; R5P, ribose-5-phosphate; Ru5P, ribulose-5-phosphate; S7P, sedoheptulose-7-phosphate; X5P, xylulose-5-phosphate; PYR, pyruvate; AcCoA, acetyl-CoA; TCA, tricarboxylic acid; aroG fbr, gene encoding a feedback-inhibition-resistant version of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS); tktA, transketolase; tyrB, tyrosine aminotransferase gene; PAL, phenylalanine ammonia lyase; TAL, tyrosine ammonia lyase.

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