Table 1 Biosynthetic machinery of unique molecules in T. thermophilus
Molecules | No. of reactions | Genes involved | Major metabolic precursors |
|---|---|---|---|
Branched fatty acids | 19 | ilvE (TTC1870), vorA (TTC1756) and vorB (TTC1757), FabF (TTC0049 or TTC0045), FabG (TTC0047 or TTC0394), FabZ (TTC1463), FabI (TTC0343) | Leucine, valine, isoleucine and acetyl-coA |
(i-15:0, ai-15:0, i-16:0, i-17:0, ai-17:1) | |||
Carotenoids | 18 | CrtE (TTC1986), CrtB (TT_P0057), CrtI (TT_P0066), CrtY (TT_P0060), CrtZ (TT_P0059), CruC (TT_P0062), CruD (TT_P0061) | Isopentenyl diphosphate (IPP), UDP-glucose and branched fatty acids |
(thermocryptoxanthin, thermozeaxanthin and thermobiszeaxanthin) | |||
Polyamines | 16 | SpeA (TTC1277), SpeB (TTC0764 or TTC1132), SpeD1 (TTC0473), SpeD2 (TTC1093), SpeE (TTC0472) | Putrescine, spermidine and spermine |
(1,3-diaminopropane, norspermidine, sym-homospermidine, thermine, thermospermine, homospermine, caldopentamine, thermopentamine, homocaldopentamine, caldohexamine, homocaldohexamine, tris(3-aminopropyl)amine, tetrakis(3-aminopropyl)ammonium) | Â | Â | Â |