Skip to main content
Figure 2 | Microbial Cell Factories

Figure 2

From: Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in Escherichia coli

Figure 2

Extensive metabolic remodeling is achieved through CsrB manipulation. Average fold ratio of intracellular metabolites and proteins from central metabolism in BLR-DAJ cells bearing pBbA5C-CsrB relative to the empty plasmid (pBbA5C) alone (see Methods for details). Certain metabolites and proteins were not analyzed (black). Fold level changes represented by colored fonts (for metabolites) or colored boxes (for proteins) corresponding to the gradient shown on the right (see Additional file 2: Table S2 and Additional file 6: Table S3). CsrA targets with potential or known binding sites are depicted by a brown outline around the corresponding protein box. Pentose phosphate (penP), erythrose-4-phosphate, (E4P), glyceraldehyde-3-phosphate (G3P), 3-phosphoglycerate (3PG), phosphoenolpyruvate (PEP), pyruvate (pyr), acetyl-CoA (acCoA), oxaloacetate (oaa), citrate (cit), iso-citrate (i-cit), a-ketoglutarate (akg), glyoxylate (glx), succinyl-CoA (sucCoA), succinate (suc), malate (mal), fumarate (fum).

Back to article page

Microbial Cell Factories

ISSN: 1475-2859

Contact us