Figure 1From: Construction of a cellulase hyper-expression system in Trichoderma reesei by promoter and enzyme engineeringSchematic structure of cbh1 promoter and its mutants. There are three CREI binding sites located at -690, -698 and -724 in wild type cbh1 promoter. An ACEII binding site was replaced the CREI binding site at -724 in promoter pcbh1m1. Based on pcbh1m1, HAP2/3/5 complex binding sites were substituted for the remaining two CREI binding sites in promoter pcbh1m2.Back to article page