Carbon dioxide valorization into resveratrol via lithoautotrophic fermentation using engineered Cupriavidus necator H16

Table 2 Heterotrophic and autotrophic microbial production of resveratrol in various engineered strains

Host strain	Characteristics	Carbon source	Titer (mg/L)	Reference
C. necator H16	2xSTS, TAL, 4CL	Fructose	6.8	This study
	2xSTS, TAL, 4CL	CO₂	1.9	This study
S. elogatus	AROG, SAM8, 4CL, STS	CO₂	4.6	[40]
L. lactis	TAL,4CL, STS, ACC	Glucose	1.3	[41]
S. venezuelae	STS,4CL, Pikromycin pks deletion	Sucrose	0.4	[39]
S. cerevisiae	PAL, 4CL, STS, ACC1	Galactose	5.8	[42]
S. cerevisiae	PAL, C4H, 4CL, VST, ACS, ATR2, ARO4^fbr, ARO7^fbr, CYB5, ACC1, △ARO10	Glucose	812	[36]
Y. lipolytica	4CL, STS, PEX10, ACC1	Glucose	48.7	[43]
E. coli	PAL, 4CL, STS, ACC	Glucose	37	[44]
E. coli	TAL, 4CL, STS, ACC, GroEL, GroES, ompF, anti-fabD	Glycerol	238	[18]

ISSN: 1475-2859