Fig. 6
Resveratrol production using engineered strains from CO2 and tyrosine. Lithoautotrophic fermentation profiles of the engineered strains for resveratrol production under different gas compositions of (A, B) H2:O2:CO2 = 70:20:10 vs. (C, D) H2:O2:CO2 = 88:2:10 (O2-limited) with different initial cell densities. The MM medium was supplemented with 5 mM tyrosine for resveratrol synthesis and the expression of resveratrol-biosynthetic genes was induced by adding 0.2% (w/v) L-arabinose after 24 h of autotrophic culture. The resveratrol titer was measured at the end of 144 h-fermentation