Table 2 Genes showing more than twofold upregulation or more than threefold down regulation at 6Â h growth
From: Induction of the CtsR regulon improves Xylanase production in Bacillus subtilis
FC 6Â h | FC 3Â h | Name | Operon | Regulon | Description |
|---|---|---|---|---|---|
3400 | 2760 | xynA | Â | Â | Endo-1,4-beta-xylanase |
3 | 1.3 | sr1 |  | CcpN 100%↓ | Small RNA regulation arginine metabolism |
2.7 | 1 | ydjB | Â | Â | Prophage 3 |
2.6 | 2.7 | yuiA | yuiA (2) | TnrA 100%↓ | Unknown |
2.6 |  − 1.2 | gapB | gapB (2) | CcpN 100%↓ | Glyceraldehyde-3-phosphate dehydrogenase |
2.4 |  − 1 | ribE | ribD (5) | FMN 100%↓ | Riboflavin biosynthesis |
2.3/2.1 | 2.0/1.3 | leuB,C | ilvB (7) | CcpA 100%↑ | Biosynthesis of leucine |
2.1 | 1.2 | natA | natA (2) | NatR 100%↑ | Sodium exporter subunit |
2.1 |  − 1.1 | pckA |  | CcpN 100%↓ | Phosphoenolpyruvate carboxykinase |
2 |  − 1.2 | frlR |  |  | Regulator sugar amines utilization |
 − 13.4 |  − 3.9 | clpE |  | CtsR 100%↑ | AAA unfoldase |
 − 12.9/− 8.2 |  − 4.4/− 1.7 | melA,C,D,E,R | melR (5) | MelR 100%↑ | Melibiose utilization |
 − 10.2/− 3.0 |  − 1.6/2.0 | sboA,albB,C,D,E,F,G | sboA (9) | ResD 100%↓ | Subtilosin (antimicrobial peptide) production |
 − 7.5/− 3.5 |  − 1.4/− 2.0 | iolA,G,H,I,J | iolA (10) | IolR 100%↑ | Myo-inositol catabolism |
 − 6.6 | 1.1 | iolT |  | IolR 100%↑ | Myo-inositol uptake |
 − 6.2 | 1.7 | yebD |  |  | Unknown |
 − 5.8 |  − 1.4 | fnr |  | ResD 100%↓ | Anaerobiosis, overflow metabolism |
 − 4.8/− 3.1 |  − 2.0/− 1.2 | yojA,B | yojA (2) |  | Unknown |
 − 4.6 |  − 1.3 | trnB-Arg |  |  | Transfer RNA-Arg |
 − 4.6/− 4.4 |  − 1.1/1.0 | ycnI,J,K | ycnK (3) | YcnK 100%↑ | Regulation of copper uptake |
 − 4.6 |  − 1.0 | ctaA |  | ResD 100%↓ | Heme biosynthesis |
 − 4.6 |  − 1.0 | ydbL |  |  | Unknown |
 − 4.6/− 3.6 |  − 1.0/1.0 | qoxA,B,C,D | qoxA (4) | CitB 0%-50% | Cytochrome aa3 quinol oxidase |
 − 4.5 | 1.0 | yxaL | yxaJ (2) | Rok 100%↑ | Unknown |
 − 4.4 | 1.0 | ctaO |  | AbrB 100%↑ | Heme biosynthesis |
 − 4.4 |  − 1.0 | yodA |  |  | Unknown |
 − 4.4 | 1.2 | trnB-Leu1 |  |  | Transfer RNA-Leucine |
 − 4.0 | 1.3 | scr |  |  | 4.5S RNA of signal recognition particle (SRP) |
 − 3.8 | 1.0 | ydzA |  |  | Unknown |
 − 3.6 |  − 1.1 | yozB |  |  | Unknown |
 − 3.6/− 3.1 |  − 1.3/− 1.2 | iolR,S | iolR (2) | IolR 100%↑ | Regulation of myo-inositol catabolism |
 − 3.6 | 1.2 | yoqM |  | AbrB 100%↑ | SP-beta prophage |
 − 3.4 |  − 1.1 | ywzB | ywzB (3) | SigF 75%↓ | Unknown |
 − 3.4 |  − 1.1 | ytzI |  |  | Unknown |
 − 3.3 |  − 1.4 | yxiE | bglP (3) | LicT 100%↓ | Possible beta-glucan/-glucoside utilization |
 − 3.3 | 1.0 | yfmQ |  |  | Unknown |
 − 3.2 |  − 1.7 | yncC |  |  | Unknown |
 − 3.2/− 3.0 |  − 1.3/− 1.1 | hemE,H,Y | hemE (3) |  | Heme biosynthesis |
 − 3.1 |  − 1.2 | gabT | gabT (2) | GabR 100%↓ | Utilization of gamma-amino butyric acid |
 − 3.1 | 1.2 | sunA | sunA (5) | Rok 100%↑ | Sublancin (antimicrobial peptide) production |
 − 3.1 |  − 1.0 | ytkA | ytkA (2) |  | Unknown |