Fig. 9From: Discovery and overproduction of novel highly bioactive pamamycins through transcriptional engineering of the biosynthetic gene clusterPamamycin production by S. albus P21pamW J1074 containing different variants of the R2 cosmid. The synthetic promoters driving the expression of either pamA-pamS operons (R2-pamAp73) or pamF-pamC (R2-pamFp73) and both operons (R2-73), were transferred into the R2 cosmid. The native construct R2 was used as control. Biological triplicates were performed for this experiment (n = 3)Back to article page