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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Semi-rational engineering an aldo–keto reductase for stereocomplementary reduction of α-keto amide compounds

Fig. 3

Analysis of substrate binding pockets and interactions between ligands and proteins of iolS and variants. Binding modes of pro-S conformation to WT iolS (A) and variant I57F/F126L (B); Binding modes of pro-R conformation to variant N21A/F126A (C). Yellow: ONDPA; orange: NADPH; residues of binding pockets are shown by sticks; green: hydrogen bonds; magenta: π − π interactions; pink: π − σ and π − Alkyl interactions

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Microbial Cell Factories

ISSN: 1475-2859

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