Fig. 2From: Heterologous overproduction of oviedomycin by refactoring biosynthetic gene cluster and metabolic engineering of host strain Streptomyces coelicolor(a) Scheme of promoter refactoring of each BGC gene using in vitro CRISPR/Cas9. Purple: ermE*p; red: kasO*p. (b) LC chromatograph of oviedomycin (indicated by the dotted line)Back to article page