Fig. 5From: The transcription factor GCN4 contributes to maintaining intracellular amino acid contents under nitrogen-limiting conditions in the mushroom Ganoderma lucidumSchematic indicating that GCN4 regulates intracellular amino acid contents under low-nitrogen conditions. Under low-nitrogen conditions, GCN4 promotes the synthesis of intracellular amino acids through the transcriptional regulation of genes related to amino acid synthesis. In addition, GCN4 activates the TCA cycle and glycolytic pathway and inhibits the activity of TORC1 to replenish intracellular amino acidsBack to article page