Fig. 4
From: Cytotoxic effects of halophilic archaea metabolites on ovarian cancer cell lines
Normalized CI of cancer cell lines treated with halophilic archaea samples. A549, HepG2, SK-OV-3, A2780, A2780cis and HeLa cancer cell lines seeded at 3 × 104 cells/well were incubated for 24 h in an electronic 96-well plate at 37 °C with 5% CO2 and then treated with 10 (white bars), 100 (grey bars) or 200 µg/mL (black bars) of extracts from Nnm. salaciae (NS), Hrd. rudnickae 64T (HR64), Hrd. rudnickae 66 (HR66) or fresh culture medium extract (medium), or were left untreated (none, hatched bars) for the following 72 h. Impedance was measured every 15 min and converted to CI values. Data are presented as means ± SD at the final time point from 3 wells in 4 experiments. *p < 0.05 compared to medium