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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Impact of mixing insufficiencies on L-phenylalanine production with an Escherichia coli reporter strain in a novel two-compartment bioreactor

Fig. 3

Fed-batch production of L-phenylalanine from glycerol with E. coli 4RP in a stirred-tank bioreactor (STR) compared to the process performance in a two-compartment bioreactor (TCB). a, b show the biomass concentration and L-phenylalanine concentration, whereas c, d depict glycerol and acetate concentration. The subplots e, f visualize the oxygen transfer rates (OTR) and carbon dioxide transfer rates (CTR). The different phases are separated by the dark grey verticals. Segments with a white background represent the initial batch phase, whereas the segments with an orange background show the biomass production phase. A grey background depicts the product formation phase. The process strategies are described in the methods section

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