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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Identification and characterization of a strong constitutive promoter stnYp for activating biosynthetic genes and producing natural products in streptomyces

Fig. 6

Application of promoter stnYp for by-products elimination of tylosin A in industrial S. fradiae strains. (A) Biosynthetic pathway of tylosin A. (B) The yield ratio of tylosin C/A in recombinant strains with tylF under the control of different promoters (ermEp*, kasOp*, SP44 and stnYp). (C) The yield ratio of tylosin D/A in recombinant strains with tylI under the control of different promoters (ermEp*, kasOp*, SP44 and stnYp). (D) Quantification of tylosin A yield in recombinant strains with tylF and tylI driven by promoter stnYp. Statistical analyses were performed and marked (*, p ≤ 0.1; **, p ≤ 0.05; ***, p ≤ 0.01)

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Microbial Cell Factories

ISSN: 1475-2859

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