Fig. 14

Gene-protein-reaction rules of putative l-arabinose and d-xylose metabolism in R. toruloides incorporating all data in this study. (*): Genes with annotation uncertainty due to insufficient evidence (see Table 1); (**): Evidence suggests RK activity is solely encoded by RTO4_14368; Some reactions have multiple enzymes (yellow stars) mediating catalysis, possibly encoded by genes outside the subset depicted here. XR broad-substrate-specificity d-xylose reductase, LA4DH l-arabitol-4-dehydrogenase, LA2DH l-arabitol-2-dehydrogenase, LXR l-xylulose reductase, XDH xylitol dehydrogenase, DA4DH d-arabitol-4-dehydrogenase, DA2DH d-arabitol-2-dehydrogenase, RK d-ribulose kinase, XK d-xylulose kinase, DRPE d-ribulose-5-phosphate 3-epimerase, Xu5P d-xylulose-5-phosphate, PPP pentose phosphate pathway, Ru5P d-ribulose-5-phosphate, rxns reactions, red ‘X’ denotes that R. toruloides does not carry flux via XK under conditions tested, despite possession of an XK-encoding gene, RTO4_16850