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Fig. 7 | Microbial Cell Factories

Fig. 7

From: High throughput 13C-metabolic flux analysis of 3-hydroxypropionic acid producing Pichia pastoris reveals limited availability of acetyl-CoA and ATP due to tight control of the glycolytic flux

Fig. 7

 A. Flux map with the relative fluxes for the parental strain grown at pH 5 and pH 3.5. Metabolite abbreviations can be found in the caption of Fig. 5. B. Log2 fold-change of the relative fluxes at a culture pH of 3.5 of the strains X-33, PpHP1, PpHP6, PpHP8, PpHP15, and PpHP18 compared to the same strains grown at pH 5. The colour scale describes the Log2 fold-change at a -2 to 2 range. C. Log2 fold-change of the relative fluxes at a culture pH of 3.5 of the strains PpHP1, PpHP6, PpHP8, PpHP15, and PpHP18 compared to the parental strain. The colour scale describes the Log2 fold-change at a -1 to 1 range. ‘MCR’ fluxes fold-change are compared to PpHP1. The upper bound of the colour scale of the ‘MCR’ flux is set to 4

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Microbial Cell Factories

ISSN: 1475-2859

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