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Fig. 4 | Microbial Cell Factories

Fig. 4

From: High throughput 13C-metabolic flux analysis of 3-hydroxypropionic acid producing Pichia pastoris reveals limited availability of acetyl-CoA and ATP due to tight control of the glycolytic flux

Fig. 4

Reaction flux Log2 fold-change between each one of the ten 3-HP-producing recombinant strains compared to the reference strain (X-33). All colours are referred to the − 1 to + 1 colour scale, except the flux of the ‘MCR’ reaction, where the upper boundary of the colour scale is set to + 4. Moreover, in the case of ‘MCR’, the Log2 fold-change of the fluxes is referred to the flux of strain PpHP1. YX/S is the biomass to substrate yield. The reaction stoichiometry corresponding to each reaction abbreviation can be found in the Supplementary File S3

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