Table 1 List of genes deleted to optimize secretory pathway in this study *SNARE: Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor
GENE | UNIPROT ANNOTATION |
|---|---|
ROX1 | Aerobic transcriptional repression of hypoxia induced genes |
PAH1 | Nuclear/ER membrane growth, lipid droplet formation, triacylglycerol synthesis |
DER1 | Export of misfolded polypeptides to ERAD |
HRD1 | Ubiquitination of misfolded polypeptides destined for ERAD |
GOS1 | v-SNARE protein involved in Golgi transport |
OCH1 | Initiation of the polymannose outer chain elongation of N-linked oligosaccharides |
MNN9 | Elongation of the polysaccharide mannan backbone |
VPS5 | Localization of membrane proteins from a prevacuolar endosomal compartment back to Golgi |
VPS17 | Localization of membrane proteins from a prevacuolar endosomal compartment back to Golgi |
TDA3 | Oxidoreductase involved in endosome to Golgi transport |
YPS1 | Aspartic protease |
PRB1 | Proteinase B |
PEP4 | Proteinase A |
APE1 | Aminopeptidase |