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Table 1 Mutations in genes of MT strain

From: Involvement of a flavoprotein, acetohydroxyacid synthase, in growth and riboflavin production in riboflavin-overproducing Ashbya gossypii mutant

Gene

Product

DNA changes

Protein changes

Karyotic

AGOS_AAL021W

Small subunit of acetohydroxyacid synthase (AgILV6)

c.140G > A

p.S47N

Hetero

AGOS_AAL021W

Small subunit of acetohydroxyacid synthase (AgILV6)

c.155G > A

p.S52N

Hetero

AGOS_AAL021W

Small subunit of acetohydroxyacid synthase (AgILV6)

c.673G > T

p.G225C

Hetero

AGOS_ACR052W

Flavoprotein subunit of succinate dehydrogenase (AgSDH1)

c.1132G > A

p.D378N

Hetero

AGOS_ACL065C

Iron-sulfur protein subunit of succinate dehydrogenase (AgSDH2)

c.224C > T

p.T75M

Hetero

AGOS_ACL065C

Iron-sulfur protein subunit of succinate dehydrogenase (AgSDH2)

c.697A > C

p.T233P

Hetero

AGOS_AEL305C

Acetohydroxyacid synthase (AgILV2)

c. 1365G > T

p.Q455H

Homo

AGOS_AFR447C

NADH:ubiquinone oxidoreductase (AgNDI1)

c.943G > A

p.V315M

Hetero

AGOS_AGR196W

Glutathione-disulfide reductase (AgGLR1)

c.1415C > A

p.S472Y

Hetero