Fig. 6
From: Improving the production of the micafungin precursor FR901379 in an industrial production strain
Effects of overexpression of the transcriptional activator mcfJ on FR901379 production. A Heatmap of the mcf gene expression profile of C. empetri MEFC09, MEFC09-∆mcfJ, and MEFC09-J; WT: C. empetri MEFC09; J: mutant strains MEFC09-J. Relative expression levels are shown as a color gradient from low (blue) to high (red). B HPLC profiles of metabolites from C. empetri MEFC09 and MEFC09-J; 1: FR901379; 2: WF11899B; 3: WF11899C. C Titers of FR901379, WF11899B, and WF11899C were quantified in C. empetri MEFC09 and MEFC09-J in shake-flask cultures; J: mutant strains MEFC09-J; WT: C. empetri MEFC09. Statistical analysis was performed by using Student’s t test (***p < 0.001)