Fig. 3
From: Improving the production of the micafungin precursor FR901379 in an industrial production strain
Reducing byproducts through overexpression of mcfF and mcfH encoding the rate-limiting enzymes. A Schematic diagrams of the overexpression of mcfF and mcfH. B HPLC profiles of extracts from MEFC09-F, MEFC09-H, and MEFC09. Titers of FR901379, WF11899B, and WF11899C in the mutant strains of MEFC09-F (C) and MEFC09-H (D) were quantified; WT: parental strain C. empetri MEFC09; F: mutant strains MEFC09-F; H: mutant strains MEFC09-H. Statistical analysis was performed by using Student’s t test (**p < 0.01)