Exploring the potential of Rhizopus oryzae AUMC14899 as a novel endophytic fungus for the production of l-tyrosine and its biomedical applications

Table 5 Cytotoxic potential of l-tyrosine

Compound	Conc (µg/ml)	Inhibition percentage (%)		IC₅₀ (µg/ml)
Compound	Conc (µg/ml)	HSF	A-431	HSF	A-431
l-tyrosine	0.5	1.4 ± 0.2	4.5 ± 0.4	> 500	230
	5	9.2 ± 0.2	11.4 ± 0.2
	50	19.6 ± 0.3	20.1 ± 0.5
	500	35.3 ± 0.2	90.2 ± 0.2

HSF: human skin fibroblast; A-431: human epidermoid skin carcinoma; IC₅₀: sample concentration at which cell growth was 50% inhibited

ISSN: 1475-2859