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Table 3 Antibacterial activity of l-tyrosine against six MDR bacterial strains

From: Exploring the potential of Rhizopus oryzae AUMC14899 as a novel endophytic fungus for the production of l-tyrosine and its biomedical applications

Strains

Zone of inhibition (mm) ± standard deviation

MIC (µg/ml)

Different concentrations of l-tyrosine (µg/ml)

10

20

30

40

50

Gram-negative bacteria

 PA-02

9.0 ± 0.5

11 ± 0.7

19 ± 0.3

28 ± 1.1

31 ± 1.0

6

 PA-09

8.0 ± 0.7

10 ± 1.0

17 ± 0.9

25 ± 0.9

28 ± 1.5

8

 KP-01

0.0 ± 0.0

8 ± 0.9

10 ± 0.4

16 ± 0.8

19 ± 0.5

15

 EC-03

8.0 ± 1.0

11 ± 0.9

15 ± 1.0

20 ± 0.8

24 ± 1.1

10

Gram-positive bacteria

 SA-03

0.0 ± 0.0

9.0 ± 1.0

10 ± 0.5

13 ± 1.0

18 ± 1.0

20

 SA-04

0.0 ± 0.0

8.0 ± 0.8

11 ± 0.6

19 ± 1.1

21 ± 0.9

15

  1. MIC: Minimum inhibitory concentration. DMSO (1%) was used as a negative control and had no effect against the tested bacteria