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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Identification of RimR2 as a positive pathway-specific regulator of rimocidin biosynthesis in Streptomyces rimosus M527

Fig. 1

Gene organization of rim gene cluster in the genome of Streptomyces rimosus M527 and rimocidin biosynthetic pathway. Module 0, Module 1, Module 2, Module 3, Module 4, type I polyketide synthase; rimK, acetyltransferase; rimJ, crotony-CoA reductase; rimH, ferredoxin; rimG, cytochrome P450 monooxygenase; rimF, aminotransferase; rimE, glycosyl transferase; rimD, cholesterol oxidase; rimC, tyrosine phosphatase; rimRl, PAS-LuxR family transcriptional regulator; rimR2, rimR3, rimR4, LAL family transcriptional regulator. The arrows in gene cluster represent putative promoters. Proposed model for rimocidin and CE-108 biosynthesis in S. diastaticus var. 108 [38]

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Microbial Cell Factories

ISSN: 1475-2859

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