Rapid combinatorial rewiring of metabolic networks for enhanced poly(3-hydroxybutyrate) production in Corynebacterium glutamicum

Table 1 Summary of polyhydroxyalkanoates (PHAs) production in C. glutamicum

PHAs	Source of the biosynthetic genes	Carbon source	Max. PHA content (wt%)	Cellular productivity^a	Refs.
PHB, poly(3-hydroxybutyrate)	R. eutropha	20 g/L glucose in LB media	12.1	0.0252	[25]
	R. eutropha	60 g/L glucose in minimal media	22.5	0.0078	[24]
	R. eutropha	60 g/L glucose in minimal media	52.5	0.0156	[28]
	R. eutropha	20 g /L glucose in minimal media	29.1	0.0404	This study
	R. eutropha	20 g/L fructose in minimal media	21	0.0292	This study
PHBV, poly(3-hydroxybutyrate-co-3-hydroxyvalerate)	R. eutropha	130 g/L glucose in minimal media	28.7	0.0023	[27]
PHBV, poly(3-hydroxybutyrate-co-3-hydroxyvalerate)	R. eutropha	60 g/L glucose in minimal media	47.2	0.0187	[54]
PLAHB, poly(lactate-co-3-hydroxybutyrate)	Pseudomonas sp., R. eturopha, Megasphaera elsdenii	60 g/L glucose in minimal media	2.4	0.0006	[12]

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