Fig. 5From: Developing a single-stage continuous process strategy for vitamin B12 production with Propionibacterium freudenreichiiContinuous bioprocess of NBRC 12391. The number of residence times is shown on the X-axis. According to the calculated addition of both fresh media and NaOH solution, each residence time corresponds to 18.2 h. Fresh media containing 100 µM DMBI addition began at residence time 0. OD600 values, glucose (g/L), acetic acid (g/L), propionic acid (g/L) and CNCbl (mg/L) are provided. Error bars represent the standard deviation of two replicatesBack to article page