Fig. 5From: Improving spinosad production by tuning expressions of the forosamine methyltransferase and the forosaminyl transferase to reduce undesired less active byproducts in the heterologous host Streptomyces albus J1074Effects of both spnS and spnP overexpression on spinosyn A and its N-desmethyl derivatives. A Schematic representation of the kas-spnP-kas-spnS and SA15-spnP-kas-spnS expression system. B Yield of spinosyn B from different gene clusters. C Yield of spinosad (spinosyns A and D) from different gene clusters. Each fermentation was done in triplicate (n = 3). Error bars represent standard deviation. Differences were analyzed by one-way ANOVA and P < 0.05 was considered statistically significant. ***P < 0.001, **P < 0.01, *P < 0.05Back to article page