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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Improving spinosad production by tuning expressions of the forosamine methyltransferase and the forosaminyl transferase to reduce undesired less active byproducts in the heterologous host Streptomyces albus J1074

Fig. 5

Effects of both spnS and spnP overexpression on spinosyn A and its N-desmethyl derivatives. A Schematic representation of the kas-spnP-kas-spnS and SA15-spnP-kas-spnS expression system. B Yield of spinosyn B from different gene clusters. C Yield of spinosad (spinosyns A and D) from different gene clusters. Each fermentation was done in triplicate (n = 3). Error bars represent standard deviation. Differences were analyzed by one-way ANOVA and P < 0.05 was considered statistically significant. ***P < 0.001, **P < 0.01, *P < 0.05

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