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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Loop pathways are responsible for tuning the accumulation of C19- and C22-sterol intermediates in the mycobacterial phytosterol degradation pathway

Fig. 2

Predicted loop pathways for differentiating the 4-AD (S5) and BA (S11) accumulations during phytosterol degradation by the Mycobacterium HGMS2 strain. choM: cholesterol oxidase gene; hsd: 3β-hydroxyl steroid dehydrogenase/isomerase gene; cyp125: cytochrome P450 gene; fad19: acyl-CoA synthetase gene; chsE3-E5: long chain acyl-CoA dehydrogenase gene; hsd4A: β-hydroxyacyl-CoA dehydrogenase gene; fadA5: acyl-CoA thiolase gene; chsH1-H2: acyl-CoA hydratase gene; lpt: thioesterase gene; dmpG/Sal: aldolase genes; hsaG: aldehyde dehydrogenase gene; opccR667/adhE/aldo: aldehyde reductase genes; kstd: 3-ketosteroid-△1-dehydrogenase gene and ksh: 3-ketosteroid-9α-hydroxylase gene. The information on all steroid intermediates is summarized in Table 2

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Microbial Cell Factories

ISSN: 1475-2859

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