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Table 2 Analysis of variance (ANOVA) of the second-order model for the experimental data from the CCD design

From: Improved natural melanin production by Aspergillus nidulans after optimization of factors involved in the pigment biosynthesis pathway

Source of variation

Sum of squares

Degrees of freedom

Mean square

F-calc

F-tab

p-value

Regression

27,195.818

20

1359.79092

4.93

2.01

0.000127**

Residual

6899.4605

25

275.978418

Lack of fit

6701.99

22

304.635714

4.63

8.66

0.11582

Pure terror

197.47

3

65.8249178

Total

34,095.28

45

    
  1. R2 = 0.7976
  2. **Significant p < 0.05