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Table 1 Reaction rates for oxidative folding in E. coli

From: A quantitative interpretation of oxidative protein folding activity in Escherichia coli

 

Reaction(s)

R2

R3

R4 (Cat1)

R4,5 (Cat2)

R5 (Cat3)

R6,7,8 (Cat2)

R6,7,8 (Cat3)

Chemostat

 Chemostat µ = 0.5

0.090

5.388

0.946

0.433

1.297

0.227

0.527

 Chemostat µ = 0.35

0.091

4.526

1.093

0.703

2.106

0.673

1.957

 Chemostat µ = 0.20

0.040

3.943

0.791

0.535

1.603

0.295

0.886

 Chemostat µ = 0.12

0.016

3.181

1.367

0.924

2.770

0.185

0.557

High Growth

 LB

0.228

6.727

1.894

0.337

1.131

0.246

0.584

 Glycerol + AA

0.199

6.708

2.519

0.471

1.151

0.364

0.371

Stress

 pH6 glucose

0.152

7.571

1.599

0.733

2.084

0.227

0.486

 42 °C glucose

0.048

6.801

1.023

0.370

1.108

0.112

0.240

 Osmotic-stress glucose

0.111

6.637

1.107

0.482

1.518

0.192

0.412

Non-stress, sub-optimal

 Acetate

0.046

2.758

0.613

0.394

1.181

0.100

0.299

 Fructose

0.079

3.230

1.061

0.425

1.149

0.187

0.301

 Fumarate

0.065

3.888

0.988

0.556

1.664

0.158

0.406

 Galactose

0.044

3.549

0.857

0.562

1.737

0.165

0.505

 Glucosamine

0.083

5.008

1.005

0.537

1.608

0.210

0.515

 Glucose

0.080

4.309

0.796

0.404

1.092

0.168

0.292

 Glycerol

0.048

5.183

0.892

0.486

1.426

0.122

0.321

 Mannose

0.072

3.599

0.722

0.320

0.960

0.119

0.321

 Pyruvate

0.042

3.351

0.896

0.576

1.726

0.104

0.312

 Succinate

0.065

3.925

0.873

0.481

1.440

0.176

0.453

 Xylose

0.077

4.400

0.772

0.413

1.059

0.145

0.344

 Median

0.07

4.35

0.97

0.48

1.43

0.18

0.41

 Range (fold)

14.3

2.7

4.1

2.9

2.9

6.7

8.2

 Inter quartile range (fold)

1.9

1.6

1.3

1.4

1.5

1.6

1.6

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Microbial Cell Factories

ISSN: 1475-2859

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