Fig. 3
From: A quantitative interpretation of oxidative protein folding activity in Escherichia coli
The oxidative folding model. (1) Synthesis of proteins with a reduced disulfide bond. In the model there are three synthesis rates, one for each difficulty category, and synthesis rates are estimated from the known steady-state abundance of proteins in each category and the growth rate. (2) Oxidation of DsbB via quinone. (3) Oxidation of DsbAr by DsbB. (4) Correct substrate oxidation by DsbAo. (5) Incorrect substrate oxidation by DsbAo. (6) Correct substrate isomerisation by DsbCGr. (7) Incorrect substrate isomerisation by DsbCGr. (8) Reduction of wrongly oxidised substrates by DsbCGr. (9) Reduction of DsbCGo by DsbD. (10) Reduction of DsbD by Thioredoxin