Table 1 Comparison of the impact of various regulation strategies on AD production
Strains | Regulation Strategies | Conversion yield (%) | Production rate (g/L/days) |
|---|---|---|---|
QC M3-A | Overexpression AccA1 | 92.6 | 0.457 |
QC M3-D | Overexpression AccD1 | 89.2 | 0.44 |
QC M3-N | Overexpression NAT | 89.3 | 0.441 |
QC M3-C | Overexpression AraC | 90.7 | 0.447 |
QC M3-AC | Co-expression AccA1 and AraC | 94.1 | 0.464 |
QC M3-ATetO | Inducible regulation AccA1 | 95.1 | 0.469 |
QC M3-ATetOC | Inducible regulation AccA1 and overexpression AraC | 96.9 | 0.655 |
MNR-prpR [7] | MCC enhancement | 90.6 | 0.628 |
MNR-prpDBC/ΔglnR [7] | GlnR knockout and MCC enhancement | 94.3 | 0.654 |
MNR-Fpcc [6] | MMC enhancement | 25.4 | 0.176 |
MNR-Fpcc-Fndh [6] | Overexpression NDH-II and MCC enhancement | 96.4 | 0.669 |