Fig. 7
Selection of mean flux control coefficients (unitless) estimated by metabolic control analysis of E. coli NT1446 pF112aroFBLKan (NT1446) and NT1259 shiACg pF112aroFBLKan (NT1259 shiA) during l-tryptophan production depicted for the enzymes phosphoserine phosphatase (psp_L), phosphoribosylpyrophosphate synthetase (prpps), indole-glycerolphosphate synthase (igps), tryptophan synthase (trps2), 3-deoxy-arabino-7-phosphoheptulosonate synthase (dahpts), 3-dehydroquinate synthase (dhqs), 3-phosphoshikimate 1-carboxyvinyltransferase (pscvt) and chorismate synthase (chors). Metabolic fluxes of chorismate and l-tryptophan biosynthesis are represented on the Y-axes. The effects of changes in enzyme activity by one percent are illustrated (positive value: enhanced metabolic flux; negative value: reduced metabolic flux). Results for NT1259 shiACg pF112aroFBLKan were previously published in [43]