Fig. 5
Intracellular concentrations (unit: mM) of dihydroxyacetone-phosphate (DHAP), pyruvate (PYR), o-Phospho-l-serine (pser_L), 3-dehydroshikimate (3DHS), shikimate 3-phosphate (S3P), chorismate (CHOR), anthranilate (ANTH), and 1-(2-carboxyphenylamino)-1-deoxy-d-ribulose 5-phosphate (CDRP) during parallelised short-term perturbation experiments in stirred-tank bioreactors with the carbon sources glycerol (GLYC), glucose (GLUC), pyruvate (PYR) and succinate (SUC). Numbers 1–3 (NT1446): steady-state conditions corresponding to three-stage feeding levels during metabolic analysis with E. coli NT1446 pF112aroFBLKan. Ref (NT1446): intracellular concentrations in the reference fed-batch process with E. coli NT1446 during metabolic analysis. Numbers 1–3 (NT1259 shiA): steady-state conditions corresponding to three-stage feeding levels during metabolic analysis with the former strain E. coli NT1259 shiACg pF112aroFBLKan, published in [43]. Ref (NT1259 shiA): Intracellular concentrations in the reference fed-batch process with the former strain E. coli NT1259 shiACg pF112aroFBLKan during metabolic analysis, published in [43]