Fig. 3From: Metabolic control analysis enables rational improvement of E. coli l-tryptophan producers but methylglyoxal formation limits glycerol-based productionGene expression (without units, relative to ftsZ control) of genes serB, aroF, aroB, trpC, trpCmt and trpB relative to ftsZ gene of samples from reference L-tryptophan production process after 27Â h (R 27Â h), 43Â h (R 43Â h), 50Â h (R 50Â h), 55Â h (R 55Â h) and 70Â h (R 70Â h) process time (IPTG for the induction of inducible genes was added 44Â h after inoculation. The samples were taken from the production process with NT1446 pF112aroFBLKan (NT1446) and likewise with NT1259 shiACg pF112aroFBLKan (NT1259 shiA) [43]. Sample timepoints for NT1259 shiACg pF112aroFBLKan were the same with maximum deviations of 1.5Â h. Results for NT1259 shiACg pF112aroFBLKan have been already published in [43]Back to article page