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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Metabolic control analysis enables rational improvement of E. coli l-tryptophan producers but methylglyoxal formation limits glycerol-based production

Fig. 1

Final total l-tryptophan amounts (unit: g) in fed-batch cultivation processes on a 15 L scale (37 °C, pH 7.0, DO  > 30% air saturation) with E. coli strains (relevant genotype variations to the reference strain NT1259 are indicated: (NT1259), NT1259 trpCmt (NT1405), NT1259 trpBA (NT1438), NT1259 trpBA trpCmt (NT1439), NT1259 trpBA trpCmt aroB (NT1445), NT1259 trpBA trpCmt serB (NT1444), NT1259 trpBA trpCmt aroB serB (NT1446). All strains carried the plasmid pF112aroFBLKan. Error bars without caps refer to standard deviations of different samples; error bars with caps represent the deviations of three technical replicates (E. coli NT1259 and E. coli NT1446). Level of significance*: 0.01 < p < 0.05

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Microbial Cell Factories

ISSN: 1475-2859

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