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Table 3 Titer, yield, productivity, residual glycerol, fermentation mode and initial glucose level for 2,3-BDO production by different engineered S. cerevisiae cell factory microorganisms reported in the literature and in this study

From: Development of an industrial yeast strain for efficient production of 2,3-butanediol

Reference

2,3-BDO titer (g/L)

Yield (g/g glucose)

Productivity (g.L−1.h−1)

By-product (Glycerol) (g/L)

Batch or Fed batch

Initial glucose (g/L)

[33]

2.29

0.113

–

–

Batch

–

[32]

96.2

0.28

0.39

 ± 30

Fed batch

100

[37]

32.0

0.367

0.403

6.00

One batch

90

[35]

72.9

0.41

1.43

0.34

Fed Batch

95

[38]

154.3

0.404

1.98

34.00

Fed batch

330

[59]

132.4

0.34

0.41

25.3

Fed batch

120

[61]

81.0

0.27

0.16

71.8

Fed batch

100.0

[31]

178.0

0.335

1.88

 > 90

Fed batch

100.0

HGS37 (this study)

130.64

0.48

1.58

8.06

Batch

280

HGS37 (this study)

133.91

0.45

1.33

7.75

Batch

310

HGS37 (this study)

119.99

0.36

0.99

6.51

Batch

340

HGS50 (this study)

121.04

0.48

1.57

10.99

Batch

250