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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Metabolic engineering of Escherichia coli for efficient production of L-5-hydroxytryptophan from glucose

Fig. 5

5-HTP production and intracellular NAD(P)H availability in HTP09-HTP14 strains with different promoters of gdhesi. a Cell growth, 5-HTP production, and L-Trp accumulation. b Yield. c Intracellular NAD(P)H/NAD(P)+ ratio. The dashed line indicates that the ratio is one. The genotype of strains: HTP10, HTP09 mbhA::PM1−12-gdhesi; HTP11, HTP09, mbhA::PM1−30-gdhesi; HTP12, HTP09 mbhA::PM1−46-gdhesi; HTP13, HTP09 mbhA::PM1−37-gdhesi; HTP14, HTP09 mbhA::PM1−93-gdhesi. The data are presented as averages, and the error bars represent standard deviations (n = 3 independent experiments). * 0.01 < P < 0.05, ** P < 0.01

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Microbial Cell Factories

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